Results 61 to 70 of about 306 (179)
, 2015 To develop new cytoprotectors to reduce the risk of second cancers caused by methotrexate-induced cytogenotoxicity, cytoprotective effects of ten kinds of phytochemicals and their combinations were evaluated by umu test combined with micronucleus assay ...
Ying Wu, Jianbo Yang, Shaobin Gu
core +1 more source
Advances in Pharmacological and Pharmaceutical Sciences, Volume 2014, Issue 1, 2014., 2014 Phytochemicals have been presumed to possess prophylactic and curative properties in several pathologies, such as arsenic‐ (As‐) induced immunosuppression. Our aim was to discover a lymphoprotective extract from Lantana grisebachii Stuck. (Verbenaceae) (LG). We assessed its bioactivity and chemical composition using cell‐based assays.
Elio A. Soria +6 more
wiley +1 more source
Pathogenesis of diarrhea in patients with COVID-19 and approaches to therapy
Лечащий Врач, 2022 Diarrhea is observed in a significant proportion of patients with SARS-CoV-2 infection, both in the acute phase and in the post-COVID period. The purpose of the review is to present current data on the epidemiology and pathogenesis of diarrhea in ...
E. A. Lyalyukova
doaj +1 more source
Phytomelatonin: Discovery, Content, and Role in Plants
Advances in Botany, Volume 2014, Issue 1, 2014., 2014 Melatonin (N‐acetyl‐5‐methoxytryptamine) is an indolic compound derived from tryptophan. Usually identified as a neurotransmitter or animal hormone, this compound was detected in plants in 1995. Interest in knowing the melatonin content of plants and its possible role therein is growing, as indicated by the increasing number of related publications ...
Marino B. Arnao, Scott Finlayson
wiley +1 more source
Diabetes mellitus and chronic coronary syndrome
Mìžnarodnij Endokrinologìčnij Žurnal, 2021 Chronic coronary syndrome is characterized by the development of episodes of ischemia due to an imbalance between needs and blood supply to the myocardium. Such episodes are usually provoked by physical or emotional stress or other stressful situations,
V.A. Serhiyenko, A.A. Serhiyenko
doaj +1 more source
Oxidative Medicine and Cellular Longevity, Volume 2013, Issue 1, 2013., 2013 Zinc or L‐NAME administration has been shown to be protector agents, decreasing oxidative stress and cell death. However, the treatment with zinc and L‐NAME by intraperitoneal injection has not been studied. The aim of our work was to study the effect of zinc and L‐NAME administration on nitrosative stress and cell death.
Victor Manuel Blanco-Alvarez +15 more
wiley +1 more source
The Role of the Pyruvate Dehydrogenase Complex in the Development of Ischemic-Reperfusion Syndrome
Кубанский научный медицинский вестник, 2022 Background. One of the key components of energy metabolism is the pyruvate dehydrogenase complex (PDC), the activity of which can be targeted by some cytoprotectors. However, their role remains unclear. It is known that the activation of the PDC in tumor
K. A. Popov +6 more
doaj +1 more source
Influence of the cytoprotective drug meldonium on diastolic dysfunction of the myocardium [PDF]
, 2023 Background: The use of myocardial cytoprotectors (meldonium) in patients with exertional angina is a scientific-practical dilemma. Material and methods: An open randomized clinical trial was conducted involving 160 patients with chronic heart faliure ...
Istrati, Valeriu +5 more
core +1 more source
Free Radical Biology and Medicine, 2017 Pulmonary-artery-hypertension (PAH) is a life-threatening and highly invalidating chronic disorder. Chronic oxidation contributes to lung damage and disease progression. Peroxiredoxin-2 (Prx2) is a typical 2-cysteine (Cys) peroxiredoxin but its role on lung homeostasis is yet to be fully defined. Here, we showed that Prx2-/- mice displayed chronic lung
Federti E +15 more
openaire +4 more sources
CardioSomatics, 2014 The review presents, as the classical data on the mechanism of action of metabolic cytoprotector trimetazidine in acute ischemia/reperfusion injury associated with a partial inhibition of the oxidation of long chain fatty acids and increased metabolism of pyruvate, as well as new concepts of reducing the level of oxidative stress, reduction of ...
M. G Glezer +2 more
openaire +2 more sources