Results 41 to 50 of about 205 (151)

Gastroprotective Value of Berries: Evidences from Methanolic Extracts of Morus nigra and Rubus niveus Fruits

Gastroenterology Research and Practice, Volume 2017, Issue 1, 2017., 2017
This study evaluated the gastroprotective value of the methanol extracts from fruits of Morus nigra L. (black mulberry (MEMN)) and Rubus niveus Thunb (raspberry (MERN)). The total phenolic compounds and flavonoids were measured, as well as the in vitro 2,2‐diphenyl‐1‐picrylhydrazyl (DPPH) free radical scavenger activity. The gastroprotective effects of
Luciane Angela Nottar Nesello, Maria Luisa Maes Lima Beleza, Marihá Mariot, Luísa Nathália Bolda Mariano, Priscila de Souza, Adriana Campos, Valdir Cechinel-Filho, Sérgio Faloni Andrade, Luísa Mota da Silva, Kazuhiko Uchiyama   +9 more
wiley   +1 more source

ЦИТОПРОТЕКЦИЯ В КАРДИОЛОГИИ: ДОСТИГНУТЫЕ УСПЕХИ И ПЕРСПЕКТИВЫ. Часть 2

Архивъ внутренней медицины, 2014
The article is devoted to a new direction in medical treatment of ischemic heart disease and arterial hypertension — the use of cytoprotective and antioxidant agents. The intracellular mechanisms of development of hypoxia and ischemia, fabrics, oxidative
В. П. Михин
doaj   +1 more source

CYTOPROTECTIVE EFFECT OF MELDONIUM ON CARDIOMYOCYTE

Arta Medica, 2023
Background. The use of myocardial cytoprotectors (meldonium) in patients with exertional angina is a scientific-practical dilemma. Material and methods. An open randomized clinical trial was conducted involving 160 patients with chronic heart failure (
Olga Chetruș
doaj   +1 more source

The Effect of the Cytoprotector Rebamipid on the Activity of Disaccharidases in Patients with Enteropathy with Impaired Membrane Digestion [PDF]

Effective Pharmacotherapy, 2021
ENMP (enteropathy with impaired membrane digestion) is a new nosological form of pathology of the small intestine, which is based on a decrease in the activity of small intestine carbohydraz. The clinical picture of ENMA is very similar to irritable bowel syndrome, but it differs in the etiotropic relationship of symptoms with intolerance to products ...
E.V. Baulo, N.I. Belostotsky, O.V. Akhmadullina, S.V. Bykova, E.A. Sabelnikova, A.I. Parfenov   +5 more
openaire   +1 more source

Microbial and Natural Metabolites That Inhibit Splicing: A Powerful Alternative for Cancer Treatment

BioMed Research International, Volume 2016, Issue 1, 2016., 2016
In eukaryotes, genes are frequently interrupted with noncoding sequences named introns. Alternative splicing is a nuclear mechanism by which these introns are removed and flanking coding regions named exons are joined together to generate a message that will be translated in the cytoplasm. This mechanism is catalyzed by a complex machinery known as the
Nancy Martínez-Montiel, Nora Hilda Rosas-Murrieta, Mónica Martínez-Montiel, Mayra Patricia Gaspariano-Cholula, Rebeca D. Martínez-Contreras, Yiannis Kourkoutas   +5 more
wiley   +1 more source

Role of Endogenous Sulfur Dioxide in Regulating Vascular Structural Remodeling in Hypertension

Oxidative Medicine and Cellular Longevity, Volume 2016, Issue 1, 2016., 2016
Sulfur dioxide (SO2), an emerging gasotransmitter, was discovered to be endogenously generated in the cardiovascular system. Recently, the physiological effects of endogenous SO2 were confirmed. Vascular structural remodeling (VSR), an important pathological change in many cardiovascular diseases, plays a crucial role in the pathogenesis of the ...
Jia Liu, Yaqian Huang, Selena Chen, Chaoshu Tang, Hongfang Jin, Junbao Du, Guangdong Yang   +6 more
wiley   +1 more source

HSP27 Inhibits Homocysteine‐Induced Endothelial Apoptosis by Modulation of ROS Production and Mitochondrial Caspase‐Dependent Apoptotic Pathway

BioMed Research International, Volume 2016, Issue 1, 2016., 2016
Objectives. Elevated plasma homocysteine (Hcy) could lead to endothelial dysfunction and is viewed as an independent risk factor for atherosclerosis. Heat shock protein 27 (HSP27), a small heat shock protein, is reported to exert protective effect against atherosclerosis. This study aims to investigate the protective effect of HSP27 against Hcy‐induced
Xin Tian, Lei Zhao, Xianjing Song, Youyou Yan, Ning Liu, Tianyi Li, Bingdi Yan, Bin Liu, Cheng I. Cheng   +8 more
wiley   +1 more source

Synthesis of dichloroacetamides and study of their anti-tumor activity

Фармацевтичний журнал, 2022
Dichloroacetic acid and its derivatives exhibit the properties of metabolic cytoprotectors and apoptosis inducers. Nowadays evaluation of these derivatives is being conducted regarding the induction of immunogenic cell death.
L. M. Havryshchuk, V. Ya. Horishny, R. B. Lesyk   +2 more
doaj   +1 more source

Stem Cells and Regenerative Medicine: Myth or Reality of the 21th Century

Stem Cells International, Volume 2015, Issue 1, 2015., 2015
Since the 1960s and the therapeutic use of hematopoietic stem cells of bone marrow origin, there has been an increasing interest in the study of undifferentiated progenitors that have the ability to proliferate and differentiate into various tissues. Stem cells (SC) with different potency can be isolated and characterised.
J.-F. Stoltz, N. de Isla, Y. P. Li, D. Bensoussan, L. Zhang, C. Huselstein, Y. Chen, V. Decot, J. Magdalou, N. Li, L. Reppel, Y. He, Juan Carlos Casar   +12 more
wiley   +1 more source

Potential use of methylmethionine sulfonium chloride as a component of combination therapy for peptic ulcer and gastroduodenitis

Медицинский совет, 2018
It is known that gastritis, gastroduodenitis and peptic ulcer belong to the group of acid-dependent diseases, which occupy a significant proportion among the digestive system diseases.
I. G. Pakhomova
doaj   +1 more source