Results 31 to 40 of about 205 (151)

Intestinal barrier and dermatological diseases

open access: yesЛечащий Врач, 2021
The purpose of the review is to analyze the literature data on the relationship between intestinal microbiocenosis disorders and skin diseases, as well as the effect of diet on the skin condition and features of the course of certain dermatological ...
V. A. Okhlopkov   +4 more
doaj   +1 more source

Melatonin as a chronobiotic/cytoprotector: its role in healthy aging [PDF]

open access: yesBiological Rhythm Research, 2018
Abstract: Preservation of sleep, a proper nutrition and adequate physical exercise are key elements for healthy aging. Aging causes sleep alterations, and in turn, sleep disturbances lead to numerous pathophysiological changes that accelerates the aging process.
openaire   +2 more sources

Chronic heart failure: prevention and treatment options

open access: yesМедицинский совет, 2013
The problem of chronic heart failure remains relevant today. According to the Age of CHF study, the prevalence of this disease in this country is 12%. In 66% of cases CHF has ischemic etiology.
S. B. Migutina
doaj   +1 more source

Priming Low-Dose Gamma Irradiation Increases Cellular Radioadaptation Response through the Induction of Hsp70 and SOD2

open access: yesAtom Indonesia, 2021
Exposure to low-dose radiation has been demonstrated to stimulate increased cell protection when receiving subsequent challenge dose in what is known as radioadaptation response.
S. Supriyadi
doaj   +1 more source

Sulforaphane: Its “Coming of Age” as a Clinically Relevant Nutraceutical in the Prevention and Treatment of Chronic Disease

open access: yesOxidative Medicine and Cellular Longevity, Volume 2019, Issue 1, 2019., 2019
A growing awareness of the mechanisms by which phytochemicals can influence upstream endogenous cellular defence processes has led to intensified research into their potential relevance in the prevention and treatment of disease. Pharmaceutical medicine has historically looked to plants as sources of the starting materials for drug development; however,
Christine A. Houghton, Maura Palmery
wiley   +1 more source

Study of rat hepatocytes in primary culture submitted to hypoxia and reoxygenation: action of the cytoprotectors prostaglandin E1, superoxide dismutase, allopurinol and verapamil Estudo de hepatócitos de rato em cultura primária submetidos a hipóxia e reoxigenação: ação dos citoprotetores prostaglandina E1, superóxido dismutase, alopurinol e verapamil

open access: yesArquivos de Gastroenterologia, 2009
CONTEXT: Exposure of hepatocytes to pathological conditions in a microenvironment of hypoxia and reoxygenation is very frequent in hepatic diseases.
Dahir Ramos de Andrade Jr.   +2 more
doaj   +1 more source

Repression of c-myc gene expression by the thiol and disulfide forms of the cytoprotector amifostine [PDF]

open access: yesCarcinogenesis, 1997
The clinically approved cytoprotector amifostine, designated WR-2721, [S-2-(3-aminopropylamino)ethylphosphorothioic acid], protects against both radiation and drug-induced mutagenesis in animal systems. These effects extend over a wide concentration range making amifostine a strong candidate for evaluation as a possible cancer chemopreventive agent. To
S C, Liu   +3 more
openaire   +2 more sources

Recent Advances in the Pharmacological Activities of Dioscin

open access: yesBioMed Research International, Volume 2019, Issue 1, 2019., 2019
Dioscin is a typical saponin with multiple pharmacological activities. The past few years have seen an emerging interest in and growing research on this pleiotropic saponin. Here, we review the emerging pharmacological activities reported recently, with foci on its antitumor, antimicrobial, anti‐inflammatory, antioxidative, and tissue‐protective ...
Longfei Yang   +6 more
wiley   +1 more source

Cannabis sativa L. and Nonpsychoactive Cannabinoids: Their Chemistry and Role against Oxidative Stress, Inflammation, and Cancer

open access: yesBioMed Research International, Volume 2018, Issue 1, 2018., 2018
In the last decades, a lot of attention has been paid to the compounds present in medicinal Cannabis sativa L., such as Δ9‐tetrahydrocannabinol (Δ9‐THC) and cannabidiol (CBD), and their effects on inflammation and cancer‐related pain. The National Cancer Institute (NCI) currently recognizes medicinal C.
Federica Pellati   +6 more
wiley   +1 more source

Sestrin2 as a Novel Biomarker and Therapeutic Target for Various Diseases

open access: yesOxidative Medicine and Cellular Longevity, Volume 2017, Issue 1, 2017., 2017
Sestrin2 (SESN2), a highly conserved stress‐inducible metabolic protein, is known to repress reactive oxygen species (ROS) and provide cytoprotection against various noxious stimuli including genotoxic and oxidative stress, endoplasmic reticulum (ER) stress, and hypoxia.
Mazhar Pasha   +5 more
wiley   +1 more source

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