Results 31 to 40 of about 306 (179)
Changes in Metabolic Regulation and the Microbiota Composition after Supplementation with Different Fatty Acids in db/db Mice. [PDF]
Int J Food Sci, 2022 Introduction. The effects of fatty acids on health vary and depend on the type, amount, and route of consumption. EPA and DHA have a defined role in health, unlike coconut oil. Objective. The aim was to investigate the changes in metabolic regulation and the composition of the culture‐dependent microbiota after supplementation with different fatty ...
Martínez-Carrillo BE +6 more
europepmc +2 more sources
Cardioprotective measures in patients with cardiovascular risk factors and polymorbidity
Лечащий Врач, 2022 4th international educational forum «Russian Days of the Heart» took place in St. Petersburg, 22 June 2022. Its program included a satellite symposium «Actual cardioneurology: cardiovascular risk factors and polymorbidity» that was held with the support ...
article Editorial
doaj +1 more source
New data on well-known drug: focus on meldonium
Медицинский совет, 2021 The article reviews the efficacy of meldonium in patients with various diseases, which are based on secondary mitochondrial dysfunction. Mitochondria are complex cellular organelles that control many metabolic processes, including fatty acid oxidation ...
M. E. Statsenko +2 more
doaj +1 more source
Melatonin Ameliorates Cyclophosphamide‐Induced Spermatogenesis Disorder by Reducing Pyroptosis
Andrologia, Volume 2023, Issue 1, 2023., 2023 As a chemotherapeutic drug, cyclophosphamide (CP) has a negative impact on male fertility due to its reproductive toxicity. Melatonin (Mel) promotes the male reproductive system and increases testosterone synthesis. This study is aimed at exploring the molecular mechanism of Mel as a protector of male fertility against CP‐induced cytotoxicity.
Zhan Song +6 more
wiley +1 more source
Food Bioengineering, Volume 1, Issue 3-4, Page 298-306, December 2022., 2022 Whey protein was enzymatically hydrolyzed using an ultrahigh‐pressure synergistic enzymolysis method. The identified amino acid sequences were then synthesized, and their antioxidants and DPP‐IV inhibitory activities were determined. Whey protease hydrolysates could potentially be expected to be successfully commercially developed as functional ...
Zheng Yuanrong, Pang Jiakun, Liu Zhenmin
wiley +1 more source
Autophagy in the retinal pigment epithelium: a new vision and future challenges
The FEBS Journal, Volume 289, Issue 22, Page 7199-7212, November 2022., 2022 RPE cells have different systems (mitophagy, ER‐phagy, xenophagy, lipophagy, ribophagy, pexophagy, aggrephagy, and LAP) for breaking down and recycling damaged materials, allowing them to reduce ‘waste’ and reuse the ‘raw material’. Autophagosomes and phagosomes work as recycler and they take care of the cellular waste transport to the ‘incinerator ...
Daniela Intartaglia +2 more
wiley +1 more source
Gasdermins mediate cellular release of mitochondrial DNA during pyroptosis and apoptosis
The FASEB Journal, Volume 35, Issue 8, August 2021., 2021 Abstract Pyroptosis and intrinsic apoptosis are two forms of regulated cell death driven by active caspases where plasma membrane permeabilization is induced by gasdermin pores. Caspase‐1 induces gasdermin D pore formation during pyroptosis, whereas caspase‐3 promotes gasdermin E pore formation during apoptosis.
Carlos de Torre‐Minguela +3 more
wiley +1 more source
Antioxidant activity of alkoxy derivatives of (quinoline-4-ylthio)carboxylic acids [PDF]
The Ukrainian Biochemical Journal, 2015 A selection of potential bioactive molecules including alkoxy derivatives of (quinoline-4-ylthio)carboxylic acids using virtual screening has been carried out and their biological activity was determined.
O. О. Brazhko +4 more
doaj +1 more source
EFFECTIVENESS OF MELDONIUMIN IN CHRONIC HEART FAILURE PATIENTS
Медицинский совет, 2017 This article discusses the relevance of the high mortality of cardiovascular diseases (CVD) and their complications. Provides an overview of research conducted in the field of treatment of chronic heart failure and other cardiovascular diseases.
G. N. Gorokhovskaya +4 more
doaj +1 more source