Results 51 to 60 of about 205 (151)
Phytochemicals have been presumed to possess prophylactic and curative properties in several pathologies, such as arsenic‐ (As‐) induced immunosuppression. Our aim was to discover a lymphoprotective extract from Lantana grisebachii Stuck. (Verbenaceae) (LG). We assessed its bioactivity and chemical composition using cell‐based assays.
Elio A. Soria +6 more
wiley +1 more source
Pathogenesis of diarrhea in patients with COVID-19 and approaches to therapy
Diarrhea is observed in a significant proportion of patients with SARS-CoV-2 infection, both in the acute phase and in the post-COVID period. The purpose of the review is to present current data on the epidemiology and pathogenesis of diarrhea in ...
E. A. Lyalyukova
doaj +1 more source
Phytomelatonin: Discovery, Content, and Role in Plants
Melatonin (N‐acetyl‐5‐methoxytryptamine) is an indolic compound derived from tryptophan. Usually identified as a neurotransmitter or animal hormone, this compound was detected in plants in 1995. Interest in knowing the melatonin content of plants and its possible role therein is growing, as indicated by the increasing number of related publications ...
Marino B. Arnao, Scott Finlayson
wiley +1 more source
Diabetes mellitus and chronic coronary syndrome
Chronic coronary syndrome is characterized by the development of episodes of ischemia due to an imbalance between needs and blood supply to the myocardium. Such episodes are usually provoked by physical or emotional stress or other stressful situations,
V.A. Serhiyenko, A.A. Serhiyenko
doaj +1 more source
Zinc or L‐NAME administration has been shown to be protector agents, decreasing oxidative stress and cell death. However, the treatment with zinc and L‐NAME by intraperitoneal injection has not been studied. The aim of our work was to study the effect of zinc and L‐NAME administration on nitrosative stress and cell death.
Victor Manuel Blanco-Alvarez +15 more
wiley +1 more source
The Role of the Pyruvate Dehydrogenase Complex in the Development of Ischemic-Reperfusion Syndrome
Background. One of the key components of energy metabolism is the pyruvate dehydrogenase complex (PDC), the activity of which can be targeted by some cytoprotectors. However, their role remains unclear. It is known that the activation of the PDC in tumor
K. A. Popov +6 more
doaj +1 more source
New strategy for gastrointestinal protection based on gaseous mediators application
The aim of review. To assess protective mechanisms and efficacy of gaseous mediators based antiinflammatory therapy. Key points. Nowadays there are no reasonable and effective methods of prevention and treatment of NSAID-induced intestinal lesions.
O. N. Sulaieva, J. L. Wallace
doaj +1 more source
This article is focused on myocardial cytoprotectors - mildronate and trimethazidine (Preductal MB) - influence on free-radical myocardial processes in stable angina patients before and after transluminal coronary angioplasty and coronary stenting ...
I. G. Gordeev +6 more
doaj
The review presents, as the classical data on the mechanism of action of metabolic cytoprotector trimetazidine in acute ischemia/reperfusion injury associated with a partial inhibition of the oxidation of long chain fatty acids and increased metabolism of pyruvate, as well as new concepts of reducing the level of oxidative stress, reduction of ...
M. G Glezer +2 more
openaire +2 more sources
Pulmonary-artery-hypertension (PAH) is a life-threatening and highly invalidating chronic disorder. Chronic oxidation contributes to lung damage and disease progression. Peroxiredoxin-2 (Prx2) is a typical 2-cysteine (Cys) peroxiredoxin but its role on lung homeostasis is yet to be fully defined. Here, we showed that Prx2-/- mice displayed chronic lung
Federti E +15 more
openaire +4 more sources

