Results 161 to 170 of about 52,861 (267)

Correlation of cytosine arabinoside-induced increment in growth fraction of leukemic blast cells with clinical response [PDF]

, 1974
William R. Vogler, Lawrence E. Cooper, D.P. Groth   +2 more
openalex   +1 more source

Methylation of DNA in early development: 5-methyl cytosine content of DNA in sea urchin sperm and embryos [PDF]

, 1978
James M. Pollock, Marcia Swihart, Taylor J.Herbert   +2 more
openalex   +1 more source

A Cytotoxic Indazole‐based Gold(III) Carboxamide Pincer Complex Targeting DNA Through Dual Binding Modes of Groove Binding and Alkylation

Chemistry – A European Journal, EarlyView.
Toward new gold(III) anticancer agents. Herein, we report on an indazole‐based gold(III) carboxamide pincer complex exhibiting significant cytotoxicity, likely mediated through dual interactions with DNA. Mechanistic investigations suggest that the complex binds to the DNA and forms specific interactions with nucleotide bases.
Rufaro Razuwika, Sheldon Sookai, Ruth Aronson, Mandeep Kaur, Orde Q. Munro   +4 more
wiley   +1 more source

A proteome‐scale analysis of vertebrate protein amino acid occurrence: Thermoadaptation shows a correlation with protein solvation but less so with dynamics

Proteins: Structure, Function, and Bioinformatics, Volume 91, Issue 1, Page 3-15, January 2023., 2023
Abstract Despite differences in behaviors and living conditions, vertebrate organisms share the great majority of proteins, often with subtle differences in amino acid sequence. Here, we present a simple way to analyze the difference in amino acid occurrence by comparing highly homologous proteins on a subproteome level between several vertebrate model
Zhen‐Lu Li, Matthias Buck
wiley   +1 more source

Cytosine Arabinoside Therapy for Herpes Simplex Encephalitis—Clinical Experience with Six Patients [PDF]

, 1973
Anthony W. Chow, Allan Ronald, Milan Fiala, William M. Hryniuk, Marvin L. Weil, Joseph St. Geme, Lucien B. Guze   +6 more
openalex   +1 more source

Tunable G‐Quadruplex Ligands: Azobenzene Derivatives for Light‐Controlled DNA Modulation

Chemistry – A European Journal, EarlyView.
Azobenzene (AB) is a promising light‐responsive motif for targeting G‐quadruplexes (G4 s) and enabling their light‐controlled modulation. We synthesized a series of novel AB derivatives with diverse structural variations, demonstrating that the interaction mode influences its ability to modulate G4 properties bidirectionally.
Aleksandra Matusiak, Mateusz Drąg, Marco Deiana, Mikołaj J. Janicki, Marta Dudek   +4 more
wiley   +1 more source

Effect of cytosine arabinoside on viral-specific protein synthesis in cells infected with herpes simplex virus [PDF]

, 1975
Robyn L. Ward, J G Stevens
openalex   +1 more source

A Fluorescent Aptasensor for Sensitive and Selective Determination of Epigenetic Cancer Biomarker N1‐Methyladenosine in Urine Samples

Chemistry – A European Journal, EarlyView.
Using N1‐methyladenosine, a cancer biomarker as a target, a highly selective DNA aptamer was obtained with excellent selectivity and affinity, allowing the detection with a limit of detection of 1.9 µm. Abstract N1‐methyladenosine (m1A) level in urine increases in the presence of cancer and is associated with the tumor size and stage.
Esra Bağda, Efkan Bağda, Juewen Liu
wiley   +1 more source

A SYNTHESIS OF ISOTOPIC CYTOSINE AND A STUDY OF ITS METABOLISM IN THE RAT

, 1949
Aaron Bendich, Helen. Getler, George Bosworth Brown   +2 more
openalex   +1 more source

Structural basis for inhibition of protein synthesis by the aminoacyl‐aminohexosyl‐cytosine group of antibiotics [PDF]

, 1974
Frieder W. Lichtenthaler, Gunther Trummlitz   +1 more
openalex   +1 more source