Results 261 to 270 of about 136,619 (315)
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EUKARYOTIC CYTOSINE METHYLTRANSFERASES
Annual Review of Biochemistry, 2005▪ Abstract Large-genome eukaryotes use heritable cytosine methylation to silence promoters, especially those associated with transposons and imprinted genes. Cytosine methylation does not reinforce or replace ancestral gene regulation pathways but instead endows methylated genomes with the ability to repress specific promoters in a manner that is ...
Mary Grace, Goll, Timothy H, Bestor
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Biochemistry, 1993
Previous spectroscopic studies demonstrated that the oligodeoxynucleotide d(CGC G3 GCG) undergoes a reversible cation-dependent transition between Watson-Crick (WC) hairpin and parallel-stranded "G-DNA" quadruplex structures [Hardin, C.C., Watson, T., Corregan, M., & Bailey, C. (1992) Biochemistry 31, 833-841].
C C, Hardin +3 more
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Previous spectroscopic studies demonstrated that the oligodeoxynucleotide d(CGC G3 GCG) undergoes a reversible cation-dependent transition between Watson-Crick (WC) hairpin and parallel-stranded "G-DNA" quadruplex structures [Hardin, C.C., Watson, T., Corregan, M., & Bailey, C. (1992) Biochemistry 31, 833-841].
C C, Hardin +3 more
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Theoretical Study of Cytosine−Al, Cytosine−Cu and Cytosine−Ag (Neutral, Anionic and Cationic)
The Journal of Physical Chemistry A, 2008The binding of cytosine to Al, Cu and Ag has been analyzed using the hybrid B3LYP density functional theory method. The three metals all have open shell electronic configuration, with only one unpaired valence electron. Thus it is possible to study the influence of electronic configuration on the stability of these systems.
Marco-Vinicio, Vazquez, Ana, Martínez
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The SPR Sensor Detecting Cytosine−Cytosine Mismatches
Journal of the American Chemical Society, 2003We have synthesized the first surface plasmon resonance (SPR) sensor that detects cytosine-cytosine (C[bond]C) mismatches in duplex DNA by immobilizing aminonaphthyridine dimer on the gold surface. The ligand consisting of two 2-aminonaphthyridine chromophores and an alkyl linker connecting them strongly stabilized the C[bond]C mismatches regardless of
Kobori, A +4 more
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The Full Cytosine‐Cytosine Base Paring: Self‐Assembly and Crystal Structure
Chemistry – A European Journal, 2023AbstractThe synthesis of self‐assembly systems that can mimic partial biological behaviours require ingenious and delicate design. For decades, scientists are committed to exploring new base pairing patterns using hydrogen bonds directed self‐assembly of nucleotides.
Zhongkui Li +6 more
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Tautomeric exchange in cytosine
Biochemical and Biophysical Research Communications, 1971Abstract It has long been noted that the H 5 proton of cytosine and its related derivatives exhibits unusually broad resonances in the pmr spectrum under certain conditions of temperature and solution pD. We have examined this phenomenon as a function of temperature, solution pD as well as the external magnetic field, and have shown that the line ...
G C, Lee, J H, Prestegard, S I, Chan
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Restricted rotation in crystalline cytosine and cytosine monohydrate
Transactions of the Faraday Society, 1970The n.m.r. parameters T1 and T1ρ, the spin-lattice relaxation times in the laboratory- and rotating-frames, respectively, have been utilized to study the molecular motions that occur in polycrystalline samples of cytosine and cytosine hydrate in the range 130–293 K. The deuterated analogues have also been studied.
I. Adams, G. Parry Jones, J. M. Thomas
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Enzymology of cytosine arabinoside
Medical and Pediatric Oncology, 1982The enzymes responsible for the metabolism of Ara-C and its metabolites in human cells are described. The relevance of the properties of those enzymes to the action of Ara-C is discussed.
Y C, Cheng, R L, Capizzi
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RNA (C5-cytosine) Methyltransferases
Biochemistry (Moscow), 2019The review summarizes the data on pro- and eukaryotic RNA (C5-cytosine) methyltransferases. The structure, intracellular location, RNA targets, and catalytic mechanisms of these enzymes, as well as the functional role of methylated cytosine residues in RNA are presented.
S A, Kuznetsova +4 more
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How to Distinguish Methyl-Cytosine from Cytosine with High Fidelity
Journal of Molecular Biology, 2012Methylation of cytosines in the DNA is central to the epigenetic code. The patterns along the DNA formed by these chemical marks instruct the cell which proteins to express and their faithful maintenance after replication are vital to the organism's life.
Caterina, Bianchi, Ronen, Zangi
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