Results 251 to 260 of about 160,622 (298)

The antimalarial and cytotoxic drug cryptolepine intercalates into DNA at cytosine-cytosine sites

Nature Structural Biology, 2001
Cryptolepine, a naturally occurring indoloquinoline alkaloid used as an antimalarial drug in Central and Western Africa, has been found to bind to DNA in a formerly unknown intercalation mode. Evidence from competition dialysis assays demonstrates that cryptolepine is able to bind CG-rich sequences containing nonalternating CC sites.
Lisgarten, J.N., Coll, M., Portugal, J., Wright, Colin W., Aymami, J.   +4 more
openaire   +4 more sources

Determination of 5‐methyl‐cytosine and cytosine in tumor DNA of cancer patients

ELECTROPHORESIS, 2005
AbstractThe determination of the relative methylation in DNA tumor samples, in order to evaluate the activity of some anti‐cancer drugs, has become a very important issue in the clinical field. Capillary electrophoresis (CE) applications in this area have been done previously but no good separation for model samples or tumor samples has been reported ...
Karina, Sandoval Guerrero, Alma, Revilla Vázquez, Blanca, Segura-Pacheco, Alfonso, Dueñas-Gonzalez   +3 more
openaire   +2 more sources

Synthesis and structure of cytosine dichloride cuprate: direct bonding of copper to cytosine

Acta Crystallographica Section C Crystal Structure Communications, 1990
Dichlorobis(cytosine)copper(II), [CuCl2-(C4H5N3O)2], Mr = 356.65, monoclinic, P2(1)/n, a = 8.399 (2), b = 13.773 (2), c = 10.775 (2) A, beta = 90.8 (2) degrees, V = 1246.3 (9) A3, Z = 4, Dx = 1.901 Mg m-3, lambda (Mo K alpha) = 0.7107 A, mu = 2.195 mm-1, F(000) = 716, T = 298 K, R = 0.032, wR = 0.037 for 2313 reflections greater than 2 sigma(F).
D, Tran Qui, E, Palacios
openaire   +2 more sources

The SPR sensor detecting cytosine[bond]cytosine mismatches.

Journal of the American Chemical Society, 2004
We have synthesized the first surface plasmon resonance (SPR) sensor that detects cytosine-cytosine (C[bond]C) mismatches in duplex DNA by immobilizing aminonaphthyridine dimer on the gold surface. The ligand consisting of two 2-aminonaphthyridine chromophores and an alkyl linker connecting them strongly stabilized the C[bond]C mismatches regardless of
Akio, Kobori, Souta, Horie, Hitoshi, Suda, Isao, Saito, Kazuhiko, Nakatani   +4 more
openaire   +1 more source

Cytosine Nucleotides in Liver

Hoppe-Seyler´s Zeitschrift für physiologische Chemie, 1971
W, Domschke, D, Keppler, E, Bischoff, K, Decker   +3 more
openaire   +2 more sources

Precision Medical Epigenetics

Medical Epigenetics, 2021
Xiaolong Cui, Zhou Zhang
exaly  

VARICELLA AND CYTOSINE ARABINOSIDE

The Lancet, 1970
B R, Seligman, F, Rosner
openaire   +4 more sources

AC-Motif: A DNA Motif Containing Adenine and Cytosine Repeat Plays a Role in Gene Regulation.

Nucleic Acids Research, 2021
Ambarnil Ghosh, Chin-Ju Park, Jihyeon Yu
exaly  

Polarographic behavior of cytosine

Archives of Biochemistry and Biophysics, 1962
E, PALECEK, B, JANIK
openaire   +2 more sources

Cytosine

Cold Spring Harbor Protocols, 2009
openaire   +1 more source