Results 91 to 100 of about 254,703 (199)

Triplex-mediated analysis of cytosine methylation at CpA sites in DNA

, 2014
Modified triplex-forming oligonucleotides distinguish 5-methyl cytosine from unmethylated cytosine in DNA duplexes by differences in triplex melting temperatures. The discrimination is sequence-specific; dramatic differences in stabilisation are seen for
Melvin, Tracy, Johannsen, Marie W., Brown, Tom, Gerrard, Simon R.   +3 more
core   +1 more source

DNA methylation in follicular lymphoma [PDF]

, 2010
PhDFollicular Lymphoma (FL) is a common B cell Non-Hodgkin Lymphoma with a median survival of 8-10 years. Patients frequently undergo transformation to a more aggressive lymphoma and this is associated with drastically reduced survival.
Ó Riain, Ciarán Liam
core   +2 more sources

Extensive reprogramming of cytosine methylation in Oryza allotetraploids

, 2015
Cytosine methylation is a prominent epigenetic modification in plants and it has been proposed to as causative for silencing some duplicates derived by polyploidization.
Bao, Ying, Xu, Qing
core   +1 more source

A 7-Deazaadenosylaziridine Cofactor for Sequence-Specific Labeling of DNA by the DNA Cytosine-C5 Methyltransferase M.HhaI

Molecules, 2015
DNA methyltransferases (MTases) catalyze the transfer of the activated methyl group of the cofactor S-adenosyl-l-methionine (AdoMet or SAM) to the exocyclic amino groups of adenine or cytosine or the C5 ring atom of cytosine within specific DNA sequences.
Falk Kunkel, Rudi Lurz, Elmar Weinhold
doaj   +1 more source

Molecular genetic analysis of siRNA biogenesis and function in Arabidopsis thaliana [PDF]

, 2009
In diverse eukaryotes, small RNA products of Dicer-like (DCL) proteins regulate mRNA stability or translation, and direct chromatin modifications to genomic regions, phenomena collectively known as RNA silencing.
Blevins, Todd Lucas
core   +1 more source

Lsh, chromatin remodeling family member, modulates genome-wide cytosine methylation patterns at nonrepeat sequences

, 2011
DNA methylation is critical for normal development and plays important roles in genome organization and transcriptional regulation. Although DNA methyltransferases have been identified, the factors that establish and contribute to genome-wide methylation
Kathrin Muegge, Sichuan Xi, Eunice Y. Lee, Robert Stephens, Keji Zhao, Jigui Shan, Anney Che, Theresa Geiman, Jiaqiang Huang, Alika Maunakea, Yongguang Tao, Robert M. Leighty, Victorino Briones   +12 more
core   +1 more source

Spatiotemporal DNA methylation dynamics shape megabase-scale methylome landscapes

Life Science Alliance
The guanine–cytosine content of genomic regions influences their spatial properties, resulting in various megabase-scale methylome patterns across different cell types.
Hidehiro Toh, Hiroyuki Sasaki
doaj   +1 more source

DNA cytosine methylation dynamics and functional roles in horticultural crops. [PDF]

Hortic Res, 2023
Liu P, Liu R, Xu Y, Zhang C, Niu Q, Lang Z.   +5 more
europepmc   +1 more source

Uncovering plant epigenetics: new insights into cytosine methylation in rye genomes. [PDF]

J Exp Bot, 2023
Kaur N, Nayakoti S, Brock N, Halford NG.
europepmc   +1 more source

Frequencies and variation in cytosine methylation patterns in diploid and tetraploid cytotypes of Paspalum notatum

, 2012
Paspalum notatum Flügge is a grass species organized as an agamic complex. The objective of the current research was to survey the frequencies and variation of cytosine methylation at CCGG sequences in diploid and tetraploid genotypes, and to determine ...
C. L. Quarin, G. D. L. Cervigni, J. P. A. Ortiz, M. P. Rodriguez, Cervigni, Gerardo Domingo Lucio, Rodríguez, María Pía, Quarin, Camilo Luis, Ortiz, Juan Pablo Amelio   +7 more
core   +1 more source