Results 221 to 230 of about 62,191 (286)

Theranostic Advancements in Brain Cancer: Promising Approaches for Emerging Therapy

open access: yesMedComm – Oncology, Volume 5, Issue 2, June 2026.
Strategies for improving intra‐arterial administration (A) and photodynamic therapy in brain cancer (B). Improving intra‐arterial (IA) administration and photodynamic therapy (PDT) for brain cancer involves enhancing tumor targeting and breaching the blood–brain barrier (BBB). Key strategies include super selective catheterization, using osmotic agents
Bipraban Khanra, Manoj Kumar Sarangi
wiley   +1 more source

Vipr2 Gene Expression Is Upregulated in the Nucleus Accumbens of Spontaneous Hypertensive Rats During Early Life

open access: yesNeuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
Expression of the VIP/PACAP receptor gene, Vipr2, was selectively upregulated in the nucleus accumbens of spontaneous hypertensive rats (SHRs), an animal model of ADHD, with no changes observed in DNA methylation levels at the CpG islands of the gene. This region‐specific overexpression may contribute to ADHD‐related behaviors in SHRs.
Ryota Araki   +3 more
wiley   +1 more source

Harnessing Trace Elements: Novel Radiosensitization Strategies for Enhanced Cancer Radiotherapy

open access: yesRare Metals, Volume 45, Issue 6, June 2026.
ABSTRACT Radiotherapy (RT) is one of the core methods of comprehensive cancer treatment. Globally, more than 40% of cancer patients rely on radiotherapy to achieve tumor control, cure or palliative relief. However, radiation resistance, immunosuppression and normal tissue injury limit its clinical application.
Yuhuan Zhang   +6 more
wiley   +1 more source

Wheat's war against stripe rust: Integrating host immunity, genomics and breeding for durable resistance

open access: yesThe Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Wheat (Triticum aestivum L.), a foundation of global food security, faces persistent threats from stripe rust caused by Puccinia striiformis f. sp. tritici (Pst). The pathogen thrives in cool and humid environments and regularly causes epidemics that lead to severe yield losses.
Farkhandah Jan   +11 more
wiley   +1 more source

Genetic diversity and population structure of jute mallow (Corchorus olitorius L.) global collection to guide conservation and breeding

open access: yesThe Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Understanding the genome‐wide diversity of jute mallow (Corchorus olitorius L.) is crucial for unlocking the potential of global genebank collections, enabling the discovery and use of traits that support climate resilience, improve nutrition, and increase productivity.
Abdul J. Shango   +11 more
wiley   +1 more source

The Evolving Landscape of Clinical Aging Clocks: From Epigenetic to Multi‐Omics Integration

open access: yesAging Cell, Volume 25, Issue 6, June 2026.
Multi‐omics aging clocks capture biological heterogeneity beyond single‐omics models, improving risk stratification. Key challenges include unknown biological meaning, timescale mismatches, and validation gaps. Future clocks must distinguish pathological damage from adaptive remodeling—damage accumulation is the most actionable target for anti‐aging ...
Liying Liu   +13 more
wiley   +1 more source

Cytosine DNA Methylation Is Found in

open access: yesAnalytical Chemistry, 2014
Floriana Capuano   +4 more
openaire   +1 more source

Cytosine methylation and hydroxymethylation at the leptin promoter

open access: yes
Leptin is an important hormone well known for its role in regulating energy intake and expenditure. DNA methylation levels at the leptin promoter in adult tissues appear to correlate with environmental stresses experienced during early life.
Al-Azzawi, Haneen
core  

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