Results 231 to 240 of about 62,191 (286)

CYP2E1 and CYP2D6 in Anti‐Tuberculosis Drug‐Induced Liver Injury: Mechanisms, Epigenetic Regulation, and Translational Implications

open access: yesClinical and Translational Science, Volume 19, Issue 6, June 2026.
ABSTRACT Tuberculosis (TB) continues to be a significant global health issue, with anti‐tuberculosis drug‐induced liver injury (ATDILI) representing the most frequent and severe adverse event associated with first‐line therapy. Despite extensive investigation, the mechanistic basis of ATDILI remains incompletely understood.
Pathida Prakongsup   +1 more
wiley   +1 more source

Genome‐wide and gene‐specific DNA methylation across developmental stages in Pogonomyrmex californicus: A socially polymorphic ant

open access: yesInsect Molecular Biology, Volume 35, Issue 3, Page 232-245, June 2026.
Comparison between developmental stages (larvae, pupae, worker) in Pogonomyrmex californicus revealed significant stage‐specific differences in Gene Body Methylated frequencies. Methylation sites were highly correlated between WGBS and ONT in P. californicus Genome‐wide methylation was low (~3%) and highly clustered within gene bodies (GBM), especially
Tania Chavarria‐Pizarro   +4 more
wiley   +1 more source

GPSM2 Promotes Pancreatic Cancer Progression Through METTL3‐Mediated m6A Modification of YAP1 mRNA

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.
ABSTRACT Pancreatic cancer poses a major therapeutic challenge due to its insidious onset and difficulty in early diagnosis. G‐protein signalling modulator 2 (GPSM2), a member of the G‐protein signalling regulator family, is highly expressed in various tumour tissues; however, its role in pancreatic cancer remains largely undefined.
Jiajun Xiu   +9 more
wiley   +1 more source

Levels of DNA cytosine methylation in the Drosophila genome. [PDF]

open access: yesPeerJ, 2018
Deshmukh S   +4 more
europepmc   +1 more source

Immune Evasion of Helicobacter pylori and Extra‐Gastric Cancer Risk

open access: yesJournal of Gastroenterology and Hepatology, Volume 41, Issue 6, Page 1722-1742, June 2026.
ABSTRACT Helicobacter pylori (H. pylori) is a group 1 gastric carcinogen that plays a significant role in extra‐gastric digestive system cancers. H. pylori disrupts host cell homeostasis through expression of virulence factors leading to immune evasion as well as persistent gastric mucosal colonization. H. pylori infection has been shown to play a role
Evren Doruk Engin   +2 more
wiley   +1 more source

Neuroendocrine tumours through an epigenetic lens: Emerging insights for diagnosis and treatment

open access: yesJournal of Neuroendocrinology, Volume 38, Issue 6, June 2026.
Abstract Neuroendocrine tumours (NETs) are well‐differentiated epithelial neuroendocrine neoplasms that frequently develop in the small intestine, pancreas, and lungs. NETs originate from neuroendocrine cells specialized in hormone secretion implicated in a number of physiological processes.
Victoria Jacquot   +4 more
wiley   +1 more source

Poster Sessions

open access: yes
HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

The aging paradox of Cushing's syndrome: Stress without clear senescence?

open access: yesJournal of Neuroendocrinology, Volume 38, Issue 6, June 2026.
Abstract Cushing's syndrome (CS), characterized by chronic endogenous hypercortisolism and disruption of the normal circadian cortisol rhythm, represents a unique human model for investigating the interplay between stress endocrinology and biological aging.
Israel Nunes Silveira   +1 more
wiley   +1 more source

Diversity of cytosine methylation across the fungal tree of life. [PDF]

open access: yesNat Ecol Evol, 2019
Bewick AJ   +7 more
europepmc   +1 more source

A Meta‐Analysis of the Effects of Acute Sleep Deprivation on the Cortical Transcriptome in Rodent Models

open access: yesJournal of Sleep Research, Volume 35, Issue 3, June 2026.
How does sleep deprivation affect the brain? We performed a meta‐analysis of publicly available transcriptional profiling datasets characterising the effects of sleep deprivation on cortical gene expression (n = 293 mice, 16,290 genes) and validated our results in an independent sample (n = 222 mice).
Cosette A. Rhoads   +8 more
wiley   +1 more source

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