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ABSTRACT Epigenetic modifications to DNA are proposed to underpin plastic responses to environmental change, and the manner in which DNA methylation contributes to plasticity likely differs among tissues. However, few studies have investigated tissue‐specific DNA methylation responses to ecologically relevant environmental stressors in natural settings.
Qiting Cai +4 more
wiley +1 more source
Advances in Visualizing Cytosine Methylation and Allele‐Specific Epigenetic States in Tissue Context
The ICON method enables sequence‐specific, bisulfite‐free visualization of DNA methylation through chemical recognition of methylated cytosines. Following probe hybridization under mild denaturing conditions, methylation‐dependent interstrand complexes are stabilized by covalent crosslinking.
Sohei Kitazawa +2 more
wiley +1 more source
Reassessment of Viroid RNA Cytosine Methylation Status at the Single Nucleotide Level. [PDF]
Di Serio F +3 more
europepmc +1 more source
Monitoring of haematopoietic stem cell mobilization by targeted DNA methylation analysis
British Journal of Haematology, Volume 208, Issue 6, Page 2284-2287, June 2026.
Wouter H. G. Hubens +3 more
wiley +1 more source
Cytosine Methylation Within Marine Sediment Microbial Communities: Potential Epigenetic Adaptation to the Environment. [PDF]
Rambo IM, Marsh A, Biddle JF.
europepmc +1 more source
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DNA cytosine methylation in plant development
Journal of Genetics and Genomics, 2010Cytosine bases of the nuclear genome in higher plants are often extensively methylated. Cytosine methylation has been implicated in the silencing of both transposable elements (TEs) and endogenous genes, and loss of methylation may have severe functional consequences.
Meishan Zhang, Bao Liu
exaly +3 more sources
Accurate Detection of Methylated Cytosine in Complex Methylation Landscapes
Monitoring DNA methylation can be a useful biomarker for disease diagnosis and prognosis. However, monitoring the methylation status of a specific cytosine biomarker is often confounded by heterogeneous peripheral DNA methylation. To address this issue, molecular inversion probes were designed with inosine strategically positioned to complement ...
Palanisamy, Ramkumar +2 more
openaire +6 more sources
Cytosine methylation and human cancer
Current Opinion in Oncology, 2000Abnormalities of genomic methylation patterns have been attributed a role in carcinogenesis since the early 1980s, when large-scale demethylation of the genome was thought be an early event in multistep colorectal carcinogenesis. In the 1990s, local de novo methylation (with or without global demethylation) at tumor suppressor loci was held to be ...
P M, Warnecke, T H, Bestor
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