Results 151 to 160 of about 42,535 (254)

Contribution of One‐Electron Oxidation of Purine and Pyrimidine Bases to the Photo‐ and Radiation‐Induced Damage to Cellular DNA

ChemPhysChem, Volume 27, Issue 15, 14 August 2026.
One‐electron oxidation of purine and pyrimidine bases of isolated and cellular DNA generates related reactive base radical cations that are converted into final decomposition products through deprotonation and hydration. In the case of guanine, the most susceptible nucleobase to one‐electron oxidants, 8‐hydroxy‐7,8‐dihydroguanyl radical, thus formed by
Jean Cadet, Dimitar Angelov, Paolo DI Mascio, J. Richard Wagner   +3 more
wiley   +1 more source

RBM45 Preferential Binding to m⁶A: Simulations Suggest Synergy of RRM3 and Other Domains. [PDF]

J Phys Chem B
Park R, Contreras LM, Tamamis P.
europepmc   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, Volume 16, Issue 8, Page 1509-1526, August 2026.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

The potential of methylation signal detection in eDNA toward functional ecological monitoring. [PDF]

Commun Biol
Liu C, Fei X, Hirayama IT, Yagi G, Ushio M.   +4 more
europepmc   +1 more source

Intimate Interaction Between Nucleic Acid and Conjugated Polymers in Organic Electrochemical Transistors Enables Ultrasensitive Biomarker Detection

Advanced Materials, Volume 38, Issue 43, 3 August 2026.
The intimate interaction between negatively charged RNA molecules and conjugated polymers in organic electrochemical transistors (OECTs) in aqueous electrolytes is investigated. It demonstrates that RNA binding reduces the volumetric capacitance of the polymer channel, enabling the development of an ultrasensitive biosensing platform capable of ...
Hong Liu, Naixiang Wang, Anneng Yang, Jiajun Song, Li Li, Iain McCulloch, Helen Ka‐wai Law, Feng Yan   +7 more
wiley   +1 more source

Cortisol Recognition by a Conformationally Responsive DNA Aptamer

Advanced Sensor Research, Volume 5, Issue 8, August 2026.
The full‐length 85mer cortisol aptamer intrinsically populates two metastable conformational states in equilibrium. Cortisol binding redistributes the conformational ensemble by shifting the equilibrium between open and compact states while maintaining the underlying secondary structure. This ligand‐induced tertiary reorganization provides an atomistic
Lakshitha Jasin Arachchige, Nayoon Kwon, Isoo Youn, Chang‐Seuk Lee, Tiffany R. Walsh   +4 more
wiley   +1 more source

Enzyme structure and kinetics produce tRNA and nucleotide specificity of Schizosaccharomyces pombe CC- and A-adding enzymes. [PDF]

Nucleic Acids Res
Sikkema AP, Klemm BP, Perera L, Hall TMT.   +3 more
europepmc   +1 more source

DMS‐MaPseq and DREEM Analyses Implicate the Critical Role of RNA Structural Dynamics in Turnip Yellow Mosaic Virus Pathogenicity

Advanced Science, Volume 13, Issue 43, 3 August 2026.
RNA structural profiling of Turnip Yellow Mosaic Virus by DMS‐MaPseq and DREEM analyses uncover that viral genome‐wide RSS is highly complicated and heterogeneous, with alternative RSSs widely distributed across the genome. Notably, the viral 3’ tRNA‐like structure adopts alternative conformations in vivo.
Jiaying Zhu, Changhao Li, Chisimbily Onyia, Xindi Li, Xingxing Yan, Songxiao Zhong, Taerin Oh, Xiuren Zhang   +7 more
wiley   +1 more source

Kinetic analysis of catalytic activity of G-quadruplex/hemin DNAzyme with flanking adenine nucleotides. [PDF]

Sci Rep
Udomprasert A, Chimasungkanun S, Kangsamaksin T.   +2 more
europepmc   +1 more source

G‐Quadruplexes: Structural Diversity and Emerging Roles in Biomolecular Condensation

Advanced Science, Volume 13, Issue 45, 13 August 2026.
G‐quadruplexes (G4s) fold into diverse intra‐ and intermolecular structures, positioning them as emerging regulators of biomolecular condensation. Mechanistically, G4s autonomously form condensates, act as structural platforms to initiate and stimulate condensation, or induce phase transitions.
Wenmeng Wang, Qingqing Xu, Yuxin Zhang, Fang Liu, Guangchao Sui, Dangdang Li   +5 more
wiley   +1 more source