Results 161 to 170 of about 42,535 (254)

Ancient Plumage Colour Genetics Reveal Goose Domestication and Hybridization

open access: yesAnimal Genetics, Volume 57, Issue 4, August 2026.
ABSTRACT In archaeological assemblages, differentiating the European domestic goose and its wild progenitor, the greylag goose (Anser anser), has been challenging due to their similar skeletal morphologies. A short region of mitochondrial DNA (mtDNA) analysed from ancient DNA (aDNA) has been shown to distinguish wild greylags from domestic geese, but ...
Johanna Honka   +7 more
wiley   +1 more source

Preliminary Analysis of CpG, CHG and CHH Methylation in the Mitochondrial Control Region of Dogs With Malignant Mammary Gland Tumours

open access: yesAnimal Genetics, Volume 57, Issue 4, August 2026.
ABSTRACT Canine mammary tumours (CMTs) are one of the most frequently observed malignancies in female dogs. Many studies have investigated epigenetic changes in CMT at the nuclear level, yet the role of mtDNA methylation, particularly in the D‐loop region, remains largely unexplored.
Krzysztof Kowal   +5 more
wiley   +1 more source

miR155, triplicated in Down syndrome, regulates the development of neural stem cells and GABAergic interneurons in Alzheimer's disease mouse and human iPSC models

open access: yesAlzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION Dysfunctional microRNAs and GABAergic interneurons are features of Alzheimer's disease (AD). The role of neuronal microRNA155 (miR155), elevated in both AD and Down syndrome (DS), remains unknown. METHODS We utilized in silico analyses of published databases, MIR155‐deleted and ‐overexpressing human induced pluripotent stem cell ...
Xiaodong Zhu   +10 more
wiley   +1 more source

Experimental chronic fetal hyperglucagonemia stimulates hepatic pathways for amino acid catabolism and gluconeogenesis. [PDF]

open access: yesJ Endocrinol
Tanner AR   +7 more
europepmc   +1 more source

A Modular Nucleoside Kinase Cascade for the Synthesis of Ribonucleoside Triphosphates

open access: yesBiotechnology and Bioengineering, Volume 123, Issue 8, Page 2180-2191, August 2026.
Damm et al. report standardized enzymatic cascades for production of all canonical nucleoside triphosphates from the corresponding nucleosides, using kinase‐catalyzed phosphorylation from acetyl phosphate. Reactions afforded ∼ 100 mM product in near‐quantitative conversion.
Oliver T. Damm   +3 more
wiley   +1 more source

Write and Read: Harnessing Synthetic DNA Modifications for Nanopore Sequencing. [PDF]

open access: yesACS Nano
Bertocchi U   +12 more
europepmc   +1 more source

Patient‐Derived Organoid‐Based CRISPR Screens in Cancer Research: Applications, Advances, and Challenges

open access: yesCancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Patient‐derived organoids (PDOs) have emerged as physiologically relevant cancer models that preserve key genetic, histological, and functional features of the tumors from which they are derived. In parallel, CRISPR‐based perturbation technologies have transformed functional genomics by enabling scalable interrogation of gene function.
Julianne du Plessis, Aadilah Omar
wiley   +1 more source

Incorporation of arabinose-CTP and arabinose-UTP inhibits viral polymerases by inducing long pauses. [PDF]

open access: yesJ Biol Chem
Xiao Z   +7 more
europepmc   +1 more source

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