Results 11 to 20 of about 322,139 (355)

From vesicle to cytosol

open access: yeseLife, 2018
Drugs called bisphosphonates are used to treat a range of bone diseases, but how do they reach the enzymes that are their target?
Michael J Rogers, Marcia A Munoz
doaj   +5 more sources

Sensing microbial RNA in the cytosol [PDF]

open access: yesFrontiers in Immunology, 2013
The innate immune system faces the difficult task of keeping a fine balance between sensitive detection of microbial presence and avoidance of autoimmunity.
Nicolas eVABRET, Julie Magarian eBlander
doaj   +4 more sources

Mycobacterium tuberculosis subverts the TLR-2-MyD88 pathway to facilitate its translocation into the cytosol. [PDF]

open access: yesPLoS ONE, 2014
Mycobacterium tuberculosis (M.tb) has evolved mechanisms to evade its destruction in phagolysosomes, where it successfully survives and replicates within phagocytes.
Aejazur Rahman   +4 more
doaj   +2 more sources

Cytosolic Sensing of Viruses [PDF]

open access: yesImmunity, 2013
Cells are equipped with mechanisms that allow them to rapidly detect and respond to viruses. These defense mechanisms rely partly on receptors that monitor the cytosol for the presence of atypical nucleic acids associated with virus infection. RIG-I-like receptors detect RNA molecules that are absent from the uninfected host.
Safia Deddouche   +2 more
openaire   +3 more sources

Influence of Technological Stages of Preparation of Rooster Semen for Short-Term and Long-Term Storage on Its Quality Characteristics

open access: yesCurrent Issues in Molecular Biology, 2022
There is a problem of declining quality of rooster semen in the “native semen-equilibrium-short-term and long-term storage (cryopreservation)” cycle. The aim of this study was to determine the effects of various methods of preparing rooster semen on its ...
Yulia Silyukova   +2 more
doaj   +1 more source

Calciprotein Particles Induce Cellular Compartment-Specific Proteome Alterations in Human Arterial Endothelial Cells

open access: yesJournal of Cardiovascular Development and Disease, 2023
Calciprotein particles (CPPs) are indispensable scavengers of excessive Ca2+ and PO43− ions in blood, being internalised and recycled by liver and spleen macrophages, monocytes, and endothelial cells (ECs).
Daria Shishkova   +9 more
doaj   +1 more source

Molecular cloning and characterization of nitrogen source responsive GS1 gene from melon

open access: yesBiologia Plantarum, 2011
A full-length cDNA clone encoding cytosolic glutamine synthetase (GS1; EC 6.3.1.2) was isolated from melon (Cucumis melo L.) for the first time by RT-PCR and RACE approach. The clone, designated as M-GS1 (accession No.
Y. -W. Deng   +6 more
doaj   +1 more source

Dissecting the Role of SAL1 in Metabolizing the Stress Signaling Molecule 3′-Phosphoadenosine 5′-Phosphate in Different Cell Compartments

open access: yesFrontiers in Molecular Biosciences, 2022
Plants possess the most highly compartmentalized eukaryotic cells. To coordinate their intracellular functions, plastids and the mitochondria are dependent on the flow of information to and from the nuclei, known as retrograde and anterograde signals ...
Natallia Ashykhmina   +8 more
doaj   +1 more source

Trehalose as a Stabilizer of the Lipid Composition of Membranes and the Composition of the Cytosol of Frozen/Thawed Rooster Spermatozoa

open access: yesAgriculture, 2023
Low-temperature semen storage technologies are already being used in poultry conservation programs, but the quality of reproductive material stored in cryobanks varies greatly and cannot always be successfully used for practical purposes.
Olga Stanishevskaya   +6 more
doaj   +1 more source

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