Results 11 to 20 of about 256,621 (293)

From vesicle to cytosol

open access: yeseLife, 2018
Drugs called bisphosphonates are used to treat a range of bone diseases, but how do they reach the enzymes that are their target?
Michael J Rogers, Marcia A Munoz
doaj   +5 more sources

Sensing microbial RNA in the cytosol [PDF]

open access: yesFrontiers in Immunology, 2013
The innate immune system faces the difficult task of keeping a fine balance between sensitive detection of microbial presence and avoidance of autoimmunity.
Nicolas eVABRET, Julie Magarian eBlander
doaj   +4 more sources

Cytosolic Sensing of Viruses [PDF]

open access: yesImmunity, 2013
Cells are equipped with mechanisms that allow them to rapidly detect and respond to viruses. These defense mechanisms rely partly on receptors that monitor the cytosol for the presence of atypical nucleic acids associated with virus infection. RIG-I-like receptors detect RNA molecules that are absent from the uninfected host.
Safia Deddouche   +2 more
openaire   +3 more sources

Influence of Technological Stages of Preparation of Rooster Semen for Short-Term and Long-Term Storage on Its Quality Characteristics

open access: yesCurrent Issues in Molecular Biology, 2022
There is a problem of declining quality of rooster semen in the “native semen-equilibrium-short-term and long-term storage (cryopreservation)” cycle. The aim of this study was to determine the effects of various methods of preparing rooster semen on its ...
Yulia Silyukova   +2 more
doaj   +1 more source

The activity of NADH-, NADPH- and Fd-dependent glutamate synthase in the plastids and cytosol of Pisum arvense L. root cells

open access: yesActa Societatis Botanicorum Poloniae, 2014
Three forms of glutamate synthase (NADH-GOGAT, NADPH-GOGAT and Fd-(ferredoxin) GOGAT) were found in the plastids and cytosol of Pisum arvense root cells.
Genowefa Kubik-Dobosz
doaj   +1 more source

Trehalose as a Stabilizer of the Lipid Composition of Membranes and the Composition of the Cytosol of Frozen/Thawed Rooster Spermatozoa

open access: yesAgriculture, 2023
Low-temperature semen storage technologies are already being used in poultry conservation programs, but the quality of reproductive material stored in cryobanks varies greatly and cannot always be successfully used for practical purposes.
Olga Stanishevskaya   +6 more
doaj   +1 more source

Salmonella Populations inside Host Cells

open access: yesFrontiers in Cellular and Infection Microbiology, 2017
Bacteria of the Salmonella genus cause diseases ranging from gastroenteritis to life-threatening typhoid fever and are among the most successful intracellular pathogens known.
Sónia Castanheira   +1 more
doaj   +1 more source

The Mitochondria-to-Cytosol H2O2 Gradient Is Caused by Peroxiredoxin-Dependent Cytosolic Scavenging [PDF]

open access: yesAntioxidants, 2021
Fluorescent protein-based reporters used to measure intracellular H2O2 were developed to overcome the limitations of small permeable dyes. The two major families of genetically encoded redox reporters are the reduction-oxidation sensitive green fluorescent protein (roGFP)-based proteins fused to peroxiredoxins and HyPer and derivatives.
Laura de Cubas   +4 more
openaire   +5 more sources

Calciprotein Particles Induce Cellular Compartment-Specific Proteome Alterations in Human Arterial Endothelial Cells

open access: yesJournal of Cardiovascular Development and Disease, 2023
Calciprotein particles (CPPs) are indispensable scavengers of excessive Ca2+ and PO43− ions in blood, being internalised and recycled by liver and spleen macrophages, monocytes, and endothelial cells (ECs).
Daria Shishkova   +9 more
doaj   +1 more source

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