Results 241 to 250 of about 322,139 (355)

De novo biosynthesis of taxifolin in yeast peroxisomes. [PDF]

Microb Cell Fact
Wu Q, Chen R, Zhang L.
europepmc   +1 more source

Constitutive Androstane Receptor in Macrophages Regulates Toll‐Like Receptor 4‐Mediated Innate Immune Responses Against Endotoxemic Liver Injury

Advanced Science, EarlyView.
The present study uncovers a novel role of constitutive androstane receptor (CAR) in inflammation‐mediated damage. CAR activation in macrophages inhibits proinflammatory macrophages by interacting with Tlr4, which protects against endotoxemic liver injury.
Renjie Cao, Tingting Zhao, Ying Wang, Shaofei Song, Yuan Li, Mengling Hou, Yanxin Zhang, Sengpeng Wong, Siqi Wang, Yuran Wang, Hong Peng, Min Huang, Yiming Jiang   +12 more
wiley   +1 more source

Neuronal processes contain the essential components for the late steps of ribosome biogenesis. [PDF]

Proc Natl Acad Sci U S A
Fusco CM, Staab A, Bourke AM, Tushev G, Desch K, Lins EM, Ciirdaeva E, Tom Dieck S, Kaltenschnee N, Heckel A, Langer JD, Schuman EM.   +11 more
europepmc   +1 more source

A Genetically Encoded Biosensor for Characterizing Transport and Metabolism of Glutarate

Advanced Science, EarlyView.
Here, a genetically encoded glutarate biosensor, Glusor, is developed based on transcriptional regulator CsiR. Glusor can quantify glutarate concentrations with good accuracy and precision. Then, the role of KgtP and YnfM are identified and characterized by using Glusor. Glusor also allows glutarate spatiotemporal resolution in live cells, facilitating
Kaiyu Gao, Hui Zhang, Yidong Liu, Xianzhi Xu, Wei Liu, Zhaoqi Kang, Rong Xu, Shuang Hou, Ping Han, Chuanjuan Lü, Cuiqing Ma, Ping Xu, Chao Gao   +12 more
wiley   +1 more source

Mitochondrial DNA signals driving immune responses: Why, How, Where? [PDF]

Cell Commun Signal
Giordano L, Ware SA, Lagranha CJ, Kaufman BA.   +3 more
europepmc   +1 more source

Atrial Fibroblasts‐Derived Extracellular Vesicles Exacerbate Atrial Arrhythmogenesis

Advanced Science, EarlyView.
Exosome miR‐224‐5p derived from angiotensin II‐treated atrial fibroblasts creates a substrate for AF by promoting atrial electrical remodeling. Increased exosome miR‐224‐5p enhances AF susceptibility by inhibiting CACNA1c expression and decreasing ICa current of atrial cardiomyocytes.
Yue Yuan, Xinbo Zhao, Xuejie Han, Yukai Cao, Xuexin Jin, Ling Shi, Xin Bi, Desheng Li, Yun Zhang, Wenbo Ma, Jiahui Song, Zhenwei Pan, Zhiren Zhang, Yue Li   +13 more
wiley   +1 more source

Improvement on Ferrous Ion Accumulation and Mitochondrial Dysfunction in the COVID-19 Pseudovirus-Infected Cell Model Simulating the Long COVID Status by Nutritional Strategy. [PDF]

Life (Basel)
Chen BK, Chan CH, Wang CK.
europepmc   +1 more source

An intrinsic membrane glycoprotein of the golgi apparatus with O-linked N-acetylglucosamine facing the cytosol.

, 1988
Juan M. Capasso, Claudia Abeijón, C B Hirschberg   +2 more
openalex   +1 more source

Bax Exists in a Dynamic Equilibrium between the Cytosol and Mitochondria to Control Apoptotic Priming

Molecules and Cells, 2013
Barbara Schellenberg, Pengbo Wang, James A. Keeble, Ricardo Rodriguez-Enriquez, Scott Walker, T. Owens, Fiona M. Foster, J. Tanianis-Hughes, K. Brennan, C. Streuli, A. Gilmore   +10 more
semanticscholar   +1 more source

Single‐Cell Dissection of the Biological Function and Molecular Features Underlying the Micropeptide LSMEM1 in Kidney

Advanced Science, EarlyView.
LSMEM1, an evolutionarily conserved micropeptide with extreme hydrophobicity (aliphatic index═113) and dynamic amphiphilicity (GRAVY═0.017), features a strong α‐helical transmembrane anchor (residues 64‐86). Single‐cell analysis reveals its critical role in renal lipid homeostasis.
Peimin Liu, Hong Zhang, Shanzhi Yang, Jiaoqing Li, Danfeng Wu, Haosen Xu, Huan Jiang, Yi Jing, Guoxiang Jin, Ruobing Liu, Ning Fan, Xiaoyan Bai   +11 more
wiley   +1 more source