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Cytotoxic activities of fish leucocytes

Fish & Shellfish Immunology, 2006
Like mammalian leucocytes, white blood cells of fish are able to kill altered (e.g. virus-infected) and foreign (allogeneic or xenogeneic) cells. The existence of natural killer (NK)-like and specific cytotoxic cells in fish was first shown using allogeneic and xenogeneic effector/target cell systems.
Uwe, Fischer   +5 more
openaire   +2 more sources

Cytotoxic activities of Stachys species

Fitoterapia, 2008
The cytotoxic activity of Stachys plants and of aucubin and harpagide against MCF7-breast adenocarcinoma, HeLa-cervix adenocarcinoma, A431-skin carcinoma of epithelial origin is reported in this study. Cisplatin and doxorubicin were use as reference compound.
Háznagyné Radnai Erzsébet   +7 more
openaire   +3 more sources

Specific tumoricidal activity of cytotoxic macrophages and cytotoxic lymphocytes

Cancer Immunology, Immunotherapy, 1986
The antitumor potency and specificity of syngeneic immune peritoneal exudate cells were tested. Groups of DBA/2 mice were immunized against syngeneic SL2 tumor cells. Then 6 days after the last immunization the antitumor potency, and the specificity of the immunization reaction was tested by injecting groups of the immunized mice with 10(3) to 5 X 10(7)
H F, Dullens   +5 more
openaire   +2 more sources

Cytotoxic Activity of Lymphocytes

The Journal of Immunology, 1978
Abstract To detect the cellular origins of α-lymphotoxin (α-LT), we cultured various subpopulations of human blood lymphocytes separated by erythrocyte-rosetting techniques with various mitogens. T cell-enriched subpopulations responded to PHA by increased 3H-thymidine uptake into DNA and large amounts of α-LT production.
Keisuke Yano, Zoltan J Lucas
openaire   +1 more source

Immunomodulatory and cytotoxic activities of euphol

Life Sciences, 2021
This study evaluated the effect of euphol isolated from Euphorbia umbellata (Pax) Bruyns latex on the activation of complement pathways (classical (CP), alternative (AP) and lectin (LP)), neutrophil chemotaxis, cytotoxic activity, cell morphology and death in HRT-18 and 3T3 cells lines.CP and AP were assessed using hemolytic assays and ELISA for LP ...
Thais Latansio, de Oliveira   +7 more
openaire   +2 more sources

Cytotoxic Activity of Lymphocytes

The Journal of Immunology, 1972
Abstract Antibody to human lymphotoxin was elicited in rabbits immunized with partially purified supernatants of human spleen cells stimulated by phytohemagglutinin; Anti-LT activity, assayed by neutralizing soluble LT toxicity to indicator mouse L cells, is confined to the immunoglobulin fraction of the serum; it cannot be removed by ...
Sharyn M Walker, Zoltan J Lucas
openaire   +1 more source

Cytotoxic Activity of Lymphocytes

The Journal of Immunology, 1976
Abstract Two different lymphotoxins synthesized by human blood lymphocytes stimulated with phytohemagglutin (PHA) are described. The two toxins are called α-LT and β-LT relative to their elution order on gel chromatography. Their m.w. are 75,000 and 45,000 daltons, respectively.
Sharyn M Walker   +2 more
openaire   +1 more source

Cytotoxic Activity of Lymphocytes

The Journal of Immunology, 1975
Abstract Macrophage cell-mediated cytolysis (M-CMC) of tumor cells may be measured by culturing target cells on macrophage monolayers and determining target cells on macrophage monolayers and determining target cell survival by either 86Rb or 3H-thymidine incorporation.
William P Reed, Zoltan J Lucas
openaire   +1 more source

Alloantigen-Activated CML Suppression Independent of Cytotoxic Activity

The Journal of Immunology, 1979
Abstract The generation of T cell-mediated lympholysis (CML) in murine mixed lymphocyte cultures (MLC) can be impeded if allogeneic responding and stimulating cells are incubated in the presence of lymphocytes that have been activated by prior exposure to alloantigens (1–6).
C G, Orosz, F H, Bach
openaire   +2 more sources

Antiproliferative and Cytotoxic Activities

2018
Cancer is a genetic disease, affecting many people worldwide. Chemotherapy is routinely used for cancer treatment. However, this therapeutic approach is not always effective due to the development of cell resistance and toxic effects. Plants are a reservoir of natural chemicals with chemoprotective potential against cancer and with low adverse effects.
Anesini, Claudia Alejandra   +2 more
openaire   +2 more sources

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