Results 141 to 150 of about 14,427,848 (200)

Intratumoural CD8⁺ CXCR5⁺ follicular cytotoxic T cells have prognostic value and are associated with CD19⁺ CD38⁺ B cells and tertiary lymphoid structures in colorectal cancer. [PDF]

Cancer Immunol Immunother
Wei F, Xu X, Wang J, Mei SW, Zhao FQ, Huang F, Xiao TX, Wang GJ, Wei B, Huang S, Cui W.   +10 more
europepmc   +1 more source

Immunotherapy Study on Non-small-Cell Lung Cancer (NSCLC) Combined with Cytotoxic T Cells and miRNA34a. [PDF]

Mol Pharm
Pandey R, Chiu CC, Wang LF.
europepmc   +1 more source

Selective requirement of glycosphingolipid synthesis for natural killer and cytotoxic T cells [PDF]

Cell
Tasha Morrison
exaly   +2 more sources

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Cytotoxic T cells and immunotherapy

Pediatric Radiology, 1998
Promising immunotherapies for viral infections and malignancies reflect the successful, rapid translation of laboratory findings into clinical practice. Fletcher et al. [1] present imaging studies of Epstein-Barr virus (EBV)-associated lymphomas before and after immunotherapy.
G R, Kitchingman, C, Rooney
openaire   +2 more sources

Teleost cytotoxic T cells

Fish & Shellfish Immunology, 2019
Cell-mediated cytotoxicity is one of the major mechanisms by which vertebrates control intracellular pathogens. Two cell types are the main players in this immune response, natural killer (NK) cells and cytotoxic T lymphocytes (CTL). While NK cells recognize altered target cells in a relatively unspecific manner CTLs use their T cell receptor to ...
Takuya Yamaguchi, Fumio Takizawa, Mitsuru Furihata, Veronica Soto-Lampe, Johannes M. Dijkstra, Uwe Fischer   +5 more
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Alloreactive cytotoxic T cells. I. Alloreactive and allorestricted cytotoxic T cells

European Journal of Immunology, 1985
AbstractNylon wool‐nonadherent spleen cells from three inbred mouse strains of H‐2k (CBA), H‐2d (BALB/c) and H‐2b (C57BL/6) haplotype were co‐cultured with 2,4,6‐ trinitro‐ phenyl (TNP)‐ modified or nonmodified allogeneic stimulator cells in a limiting dilution system.
J, Reimann, K, Heeg, R G, Miller, H, Wagner   +3 more
openaire   +2 more sources

Sensitivity of cytotoxic T cells to T-cell mediated cytotoxicity

Nature, 1974
LYMPHOID cells sensitised against alloantigens can lyse in vitro target cells bearing these alloantigens1,2. In most of the experimental systems using in vivo sensitised cells, T cells (thymus-dependent lymphocytes) are both necessary3 and sufficient4,5 for induction of target cell lysis.
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T-cell-mediated cytotoxicity

Current Opinion in Immunology, 1991
There are two competing theories to explain the mechanism(s) by which cytolytic T lymphocytes kill target cells: granule exocytosis of a pore-forming protein, and contact-induced internal disintegration. Accumulated evidence supports alternative pathways in lymphocytoxicity, possibly reflecting distinct effector functions expressed by different killer ...
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Natural variants of cytotoxic epitopes are T-cell receptor antagonists for antiviral cytotoxic T cells

Nature, 1994
It has been suggested that mutations within immunodominant cytotoxic T-lymphocyte (CTL) epitopes may be exploited by viruses to evade protective immune responses critical for clearance. Viral escape could originate from passive mechanisms, such as mutations within crucial CTL epitopes, either affecting major histocompatibility complex binding or T-cell
Bertoletti, A, Sette, A, Chisari, F. V, Penna, A, Levrero, M, De Carli, M, Fiaccadori, F, FERRARI, Carlo   +7 more
openaire   +4 more sources