Results 141 to 150 of about 2,965,907 (391)

Probable Primary Cutaneous CD8+ Aggressive Epidermotropic Cytotoxic T-cell Lymphoma: A Case Report of a Diagnostic Challenge [PDF]

, 2023
Marcela Velarde Loya, Monica G Millan Reza, Mariana Olaya Cordova, Zaira D Chavéz López   +3 more
openalex   +1 more source

Joint recognition by cytotoxic T cells of inactivated Sendai virus and products of the major histocompatibility complex

Journal of Experimental Medicine, 1977
Cytotoxic T cells specific for Sendai virus were generated by culturing murine spleen cells in vitro together with UV-inactivated Sendai virus. In vivo immunization of donor mice with UV-inactivated Sendai virus resulted in an in vitro secondary response
John W. Schrader, Gerald M. Edelman
semanticscholar   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Supplementary Figures 1 through 5 from Vaccines Combined with Immune Checkpoint Antibodies Promote Cytotoxic T-cell Activity and Tumor Eradication

, 2023
Omar A. Ali, Sarah A. Lewin, Glenn Dranoff, David Mooney   +3 more
openalex   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Effects of moderate-protein and high-protein diets, including mealworm meal or poultry by-product meal, on immunological variables in healthy adult dogs

BMC Veterinary Research
Background Insect meals are increasingly being used as an ingredient in diets for dogs. However, little is known about their effects on the immune function of the animals.
Sophie-Kristin Heinze, Jürgen Zentek, Kathrin Büttner, Andreas Moritz, Nadine Paßlack   +4 more
doaj   +1 more source

Data from Hypoxia-Inducible miR-210 Regulates the Susceptibility of Tumor Cells to Lysis by Cytotoxic T Cells

, 2023
Muhammad Zaeem Noman, Stéphanie Buart, Pedro Romero, Sami Ketari, Bassam Janji, Bernard Mari, Fathia Mami‐Chouaib, Salem Chouaı̈b   +7 more
openalex   +1 more source

Multiscale model for the effects of adaptive immunity suppression on the viral therapy of cancer

, 2013
Oncolytic virotherapy - the use of viruses that specifically kill tumor cells - is an innovative and highly promising route for treating cancer. However, its therapeutic outcomes are mainly impaired by the host immune response to the viral infection.
Ferreira, Silvio C, Martins, Marcelo L, Paiva, Leticia R, Silva, Hallan S   +3 more
core   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Cytotoxic T lymphocyte attacking a cancer cell (jrc_ctl-id8-2)

, 2022
Alex T. Ritter, Gleb Shtengel, C. Shan Xu, Aubrey V. Weigel, David Hoffman, Melanie Freeman, Nirmala Iyer, Nensi Alivodej, David Ackerman, COSEM Project Team, Harald F. Hess, Ira Mellman   +11 more
openalex   +1 more source