Results 181 to 190 of about 358,425 (341)

The hepatitis B virus persists for decades after patients' recovery from acute viral hepatitis despite active maintenance of a cytotoxic T–lymphocyte response [PDF]

, 1996
Barbara Rehermann, Carlo Ferrari, C Pasquinelli, Francis V. Chisari   +3 more
openalex   +1 more source

Characterizing Stage‐Specific Cellular Dynamics and Microenvironmental Remodeling in Lung Adenocarcinoma by Single‐Cell RNA Sequencing

Advanced Science, EarlyView.
This study integrated early‐stage patient specimens with publicly available datasets encompassing non‐malignant lung tissues and advanced‐stage LUAD through single‐cell sequencing, revealing a dynamically remodeled tumor microenvironment characterized by a hypoxia‐adapted malignant subset (C5), immunosuppressive LGMN+ macrophages, STAT1‐driven ...
Bomiao Qing, Xiaolan Li, Xiang He, Junyi Wang, Yi Yang, Manling Jiang, Bingbing Yan, Lei Zhang, Anying Xiong, Qin Ran, Guoping Li   +10 more
wiley   +1 more source

CD161 Characterizes an Inflamed Subset of Cytotoxic T Lymphocytes Associated with Prolonged Survival in Human Papillomavirus-Driven Oropharyngeal Cancer. [PDF]

Cancer Immunol Res, 2023
Wei Y, Xu T, Li C, Zhou X, Qian W, Shen C, Wang Q, Xing X, Ou X, He X, Yin H, Hu C, Wang Y, Ji Q, Su F, Lu X.   +15 more
europepmc   +1 more source

Glypican-3-specific cytotoxic T lymphocytes induced by human leucocyte antigen-A*0201-restricted peptide effectively kill hepatocellular carcinoma cells in vitro

, 2017
Jiangzheng Zeng, Yu Liu, Fen Huang, He Zhihui, Huamao Sun, Yanda Lu, Junhua Lei, Rongcheng Luo   +7 more
openalex   +1 more source

What Is the Role of Cytotoxic T Lymphocyte–Associated Antigen 4 Blockade in Patients with Metastatic Melanoma? [PDF]

, 2009
Caroline Robert, François Ghiringhelli
openalex   +1 more source

LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1

Advanced Science, EarlyView.
LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li, Tao Wang, Yuwen Zhong, Zhiming Wang, Wei Li, Zejian Wang, Xinyi Yang, Yu Qiao, Jianfeng Xiang, Wei Gu, Zishu Wang, Lei Sun, Feng Qian   +12 more
wiley   +1 more source

A novel decoding strategy for ProteinMPNN to design with less visibility to cytotoxic T-lymphocytes. [PDF]

Comput Struct Biotechnol J
Gasser HC, Rajan A, Alfaro JA.
europepmc   +1 more source

Splicing factor proline- and glutamine-rich regulates cytotoxic T lymphocytes-mediated cytotoxicity on non-small cell lung cancer by directly binding to PD-L1 3'UTR. [PDF]

Medicine (Baltimore), 2023
Pan Y, Cheng Y.
europepmc   +1 more source

Cytotoxic T Lymphocytes and Vaccine Development [PDF]

Journal of Biomedicine and Biotechnology, 2010
Xiao, Zhengguo, Klonowski, Kim, Yang, Hanchun   +2 more
openaire   +2 more sources

Reduction of End‐stage Malignant Glioma by Injection with Autologous Cytotoxic T Lymphocytes [PDF]

, 1999
Hideo Tsurushima, Shu Qin Liu, Koji Tuboi, Akira Matsumura, Yoshihiko Yoshii, Tadao Nose, Kaoru Saijo, Tadao Ohno   +7 more
openalex   +1 more source