Results 31 to 40 of about 733,847 (374)
Methods and compositions for stimulating T-lymphocytes [PDF]
Disclosed are methods, compositions, antibodies, and therapeutic kits for use in stimulating cytotoxic T-lymphocytes and generating immune responses against epitopes of protooncogenes.
Fisk, Bryan A.+2 more
core +1 more source
Discrete-Time System of an Intracellular Delayed HIV Model with CTL Immune Response [PDF]
In [Math. Comput. Sci. 12 (2018), no. 2, 111--127], a delayed model describing the dynamics of the Human Immunodeficiency Virus (HIV) with Cytotoxic T Lymphocytes (CTL) immune response is investigated by Allali, Harroudi and Torres. Here, we propose a discrete-time version of that model, which includes four nonlinear difference equations describing the
arxiv +1 more source
HLA-Associated viral mutations are common in human immunodeficiency virus type 1 elite controllers [PDF]
Elite controllers (EC) of human immunodeficiency virus type 1 (HTV-1) maintain viremia below the limit of detection without antiretroviral treatment. Virus-specific cytotoxic CD8+ T lymphocytes are believed to play a crucial role in viral containment ...
Block, B. L.+10 more
core +2 more sources
Influence of the age and disease colorectal in immunity cutaneous pericolostomic [PDF]
Objective: describe the immunological response in the dermal layer of the peri-colostomic region. Method: Forty-one patients with colostomies realized over eight weeks previously, were included. For the analysis of the immunocellular response in the peri-
Franco, Marcello Fabiano de+4 more
core +4 more sources
Migration of Cytotoxic T Lymphocytes in 3D Collagen Matrices [PDF]
To fulfill their killing functions, cytotoxic T lymphocytes (CTLs) need to migrate to search for their target cells in complex biological microenvironments, a key component of which is extracellular matrix (ECM). The mechanisms underlying CTL's navigation are not well understood so far.
arxiv +1 more source
Multiple myeloma is a life-threatening hematological malignancy, which is rarely curable by conventional therapies. Immunotherapy, using tumor antigen-specific, cytotoxic T-lymphocytes, may represent an alternative or additional treatment for multiple ...
Wafaa S. Khalaf+7 more
doaj +1 more source
Target cell-dependent T cell-mediated lysis of vaccinia virus-infected cells [PDF]
Vaccinia virus specific cytotoxicity against infected target cells was observed in vitro. Spleen lymphocytes from normal and immunized mice of the inbred strains C3H and DBA/2 were incubated with vaccinia virus-infected and non-infected 51Cr-labeled ...
Alkan+36 more
core +1 more source
THE ROLE OF SUBPOPULATIONS OF CD8+ T LYMPHOCYTES IN THE DEVELOPMENT OF PREGNANCY
At the present time, a broad spectrum of CD8+ T lymphocyte subsets is revealed, including naïve cells, memory cells and regulatory subpopulations. Along with cells with high cytolytic activity, some subsets with marked regulatory activity were found ...
O. I. Stepanova+5 more
doaj +1 more source
In individuals with lymphedema, diabetic foot, or other diseases, infections with saprophytes are common. The response of major cell subpopulations in the draining lymph nodes to skin infection with Staphylococcus epidermidis was assessed using the rat ...
Marta Cąkała-Jakimowicz+1 more
doaj +1 more source
Lysis mediated by T cells and restricted by H-2 antigen of target cells infected with vaccinia virus [PDF]
VARIOUS virus infections lead to the formation of cytotoxic lymphocytes (CL), which are capable of killing virus-infected target cells1−4. Specific lysis of target cells infected with 51Cr-labelled vaccinia virus could be observed when investigating the ...
GJ Hämmerling+13 more
core +1 more source