Results 41 to 50 of about 733,847 (374)
Медицинская иммунология, 2014 . Cytotoxic/pro-apoptogenic effects of IFNα-induced dendritic cells (IFN-DCs) directed against Т-lymphocytes and NK cells were investigated in healthy donors.
T. V. Tyrinova +5 more
doaj +1 more source
Journal of Experimental Medicine, 1998 Dendritic cells, but not macrophages, efficiently phagocytose apoptotic cells and cross-present viral, tumor, and self-antigens to CD8+ T cells. This in vitro pathway corresponds to the in vivo phenomena of cross-priming and cross-tolerance.
M. Albert +6 more
semanticscholar +1 more source
Perforin-mediated cytotoxicity is critical for surveillance of spontaneous lymphoma [PDF]
, 2000 Immune surveillance by cytotoxic lymphocytes against cancer has been postulated for decades, but direct evidence for the role of cytotoxic lymphocytes in protecting against spontaneous malignancy has been lacking.
Godfrey, DI +5 more
core +2 more sources
Frontiers in Immunology, 2022 miRNAs dictate relevant virus-host interactions, offering new avenues for interventions to achieve an HIV remission. We aimed to enhance HIV-specific cytotoxic responses—a hallmark of natural HIV control— by miRNA modulation in T cells.
Nadia Madrid-Elena +23 more
doaj +1 more source
Journal of Clinical Oncology, 2014 PURPOSE Tumor cells from approximately 40% of patients with Hodgkin or non-Hodgkin lymphoma express the type II latency Epstein-Barr virus (EBV) antigens latent membrane protein 1 (LMP1) and LMP2, which represent attractive targets for immunotherapy ...
C. Bollard +19 more
semanticscholar +1 more source
Discrete and continuum models for the coevolutionary dynamics between CD8+ cytotoxic T lymphocytes and tumour cells [PDF]
arXiv, 2021 We present an individual-based model for the coevolutionary dynamics between CD8+ cytotoxic T lymphocytes (CTLs) and tumour cells. In this model, every cell is viewed as an individual agent whose phenotypic state is modelled by a discrete variable. For tumour cells this variable represents a parameterisation of the antigen expression profiles, while ...
arxiv
Abnormal distribution of CD8 subpopulation in B-chronic lymphocytic leukemia identified by flow cytometry [PDF]
, 1988 We studied the occurrence of T-cell subpopulations for patients with B-cell chronic lymphocytic leukemia. The CD8+ population was divided into CD8+ suppressor (CD8a+) and CD8+ cytotoxic (CD8b+) lymphocytes using difference in orthogonal light scattering.\
B.G.De Grooth +30 more
core +2 more sources
Umbilical cord blood-derived CD11c+ dendritic cells could serve as an alternative allogeneic source of dendritic cells for cancer immunotherapy [PDF]
, 2015 Schematics for Streptamer staining. CTLs cytotoxic T lymphocytes.
Jeetendra Kumar +2 more
core +5 more sources
Acta Dermato-Venereologica, 2015 Increased expression of the cytokine interferon (IFN)-γ plays a pivotal role in vitiligo-induced depigmentation. However, the major source of IFN-γ in vitiligo patients and the mechanisms underlying melanocyte destruction are unknown.
Lili Yang +6 more
semanticscholar +1 more source
Shared determinants between virus-infected and trinitrophenyl-conjugated H-2-identical target cells detected in cell-mediated lympholysis [PDF]
, 1976 Infection of H-2-identical mice with either lymphocytic choriomeningitis (LCM) virus, vaccinia virus, or paramyxo (Sendai) virus resulted in the generation of specifically sensitized cytotoxic T lymphocytes (CTL).
Bevan +16 more
core +1 more source