Results 1 to 10 of about 686,582 (172)
Biomolecules, 2019 Drug delivery systems are molecular platforms in which an active compound is packed into or loaded on a biocompatible nanoparticle. Such a solution improves the activity of the applied drug or decreases its side effects.
Anna Janaszewska +4 more
doaj +2 more sources
Toxins, 2022 Safe working conditions must be guaranteed during waste sorting, which is crucial to maximizing recycling and reuse, in order to minimize workers’ exposure to chemical and biological hazards.
Carla Viegas +5 more
doaj +1 more source
Effect of preheating on the cytotoxicity of bulk-fill composite resins [PDF]
Journal of Dental Research, Dental Clinics, Dental Prospects, 2020 Background. Due to the effect of pre-heating on the degree of conversion of composite resins and the possible effect on cytotoxicity, the effect of pre-heating of bulk-fill composite resins was investigated on cytotoxicity in this study. Methods. In this
Mohammad Esmaeel Ebrahimi Chaharom +8 more
doaj +1 more source
Real-time cell toxicity profiling of Tox21 10K compounds reveals cytotoxicity dependent toxicity pathway linkage. [PDF]
PLoS ONE, 2017 Cytotoxicity is a commonly used in vitro endpoint for evaluating chemical toxicity. In support of the U.S. Tox21 screening program, the cytotoxicity of ~10K chemicals was interrogated at 0, 8, 16, 24, 32, & 40 hours of exposure in a concentration ...
Jui-Hua Hsieh +8 more
doaj +1 more source
Understanding of black salve toxicity by multi-compound cytotoxicity assays
BMC Complementary Medicine and Therapies, 2022 Background Black salve is a controversial complementary and alternative medicine (CAM) associated with skin toxicity and skin cancer treatment failures.
Andrew Croaker +4 more
doaj +1 more source
Frontiers in Immunology, 2020 Background: Measurement of natural killer (NK) cell function has important clinical utility in several diseases. Although the flow cytometry (FC)-based 4-h NK cytotoxicity assay using peripheral blood mononuclear cells (PBMCs) in the clinical laboratory ...
Jinho Kim +12 more
doaj +1 more source
Toxins, 2023 Background: Panton–Valentine Leukocidin sustains a strong cytotoxic activity, targeting immune cells and, consequently, perforating the plasma membrane and inducing cell death.
Abdullah AlSaleh +3 more
doaj +1 more source
Beyond gold nanoparticles cytotoxicity: potential to impair metastasis hallmarks [PDF]
European Journal of Pharmaceutics and Biopharmaceutics, Volume
157, December 2020, Pages 221-232, 2021 This study aimed to investigate the antitumor effect of ultrasmall gold nanoparticles (AuNPs), around 3 nm, stabilized by the anionic polysaccharide gum arabic (GA-AuNPs). The focus was downregulation of cancer hallmarks of aggressive tumors, using a highly metastatic model of melanoma.
arxiv +1 more source
Relationship between localization on cellular membranes and cytotoxicity of Vibrio vulnificus hemolysin. [PDF]
PLoS ONE, 2011 Vibrio vulnificus secretes a hemolysin/cytolysin (VVH) that induces cytolysis in target cells. A detergent resistant membrane domain (DRM) fraction of the cells after sucrose gradient centrifugation includes cholesterol-rich membrane microdomains which ...
Hiroyuki Sugiyama +6 more
doaj +1 more source
Cytotoxic T cells are able to efficiently eliminate cancer cells by additive cytotoxicity
Nature Communications, 2021 Lethal hit delivery by cytotoxic T lymphocytes (CTL) towards B lymphoma cells occurs as a binary, “yes/no” process. In non-hematologic solid tumors, however, CTL often fail to kill target cells during 1:1 conjugation.
B. Weigelin +8 more
semanticscholar +1 more source