Results 31 to 40 of about 712,474 (313)

Genomic Diversity and Clinical Variability in Pediatric Primary Cutaneous Anaplastic Large Cell Lymphoma: A Case Series

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger, Efrat Bar‐Ilan, Victoria Marcu, Evgeny Grishin, Rinat Yacobi, Aviv Barzilai, Hana Golan, Assaf Arie Barg   +7 more
wiley   +1 more source

Is Ozonation Treatment Efficient to Provide Safe Reclaimed Water? Assessing the Effects of Synthetic Wastewater Effluents in Human Cell Models

Applied Sciences
Ozonation has been promoted as a successful methodology for recovering effluents from wastewater treatment plants, with special emphasis on wastewater contaminated with pharmaceutical and personal care products (PPCPs).
Ana Teresa Rocha, Fátima Jesus, Helena Oliveira, João Gomes, Joana Luísa Pereira   +4 more
doaj   +1 more source

Isolation, characterization, and encapsulation of a lupeol-rich fraction obtained from the hexanic extract of Coccoloba uvifera L. leaves

Exploration of Foods and Foodomics, 2023
Aim: This study aimed to isolate, characterize, and encapsulate a lupeol-rich fraction obtained from the hexanic extract of Coccoloba uvifera L. leaves to evaluate its potential use in nutraceutical or pharmaceutical applications.
Carla N. Cruz-Salas, Zoran Evtoski, Montserrat Calderón-Santoyo, José M. Lagarón, Cristina Prieto, Juan A. Ragazzo-Sánchez   +5 more
doaj   +1 more source

Are Fertility Preservation Procedures Before Gonadotoxic Therapy and Hematopoietic Stem Cell Transplantation Feasible and Safe in Very Young Children? A Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Fertility preservation (FP) is increasingly integrated into the care of pediatric patients exposed to gonadotoxic therapy or conditioning for hematopoietic stem cell transplantation (HSCT), yet perioperative data in infants and toddlers remain scarce.
Kerstin Saalabian, Yannick Braun, Till‐Martin Theilen, Anke Barnbrock, Theresa Rohm, Fabienne Hammant, Nicole Sänger, Aynura Abbasova‐Semiz, Jan‐Henning Klusmann, Thomas Klingebiel, Udo Rolle, Peter Bader, Henning C. Fiegel, Andrea Jarisch   +13 more
wiley   +1 more source

Cytotoxicity of Printed Aligners: A Systematic Review

Dentistry Journal
Background/Objectives: The capability of printing aligners directly, eliminating the need for a dental model or thermoforming, represents a significant advancement in aligner therapy. This review aimed to assess the cytotoxicity of 3D-printed aligners to
Mauro Lorusso, Fariba Esperouz, Gabriele Di Carlo, Michele Tepedino, Rosa Esposito, Giovanni Pappalettera, Caterina Casavola, Lucio Lo Russo, Domenico Ciavarella   +8 more
doaj   +1 more source

Skin mucus of saltwater fish: a new source of antioxidant activity and cytotoxicity [PDF]

بوم‌شناسی آبزیان, 2022
Fish mucus layers are the main surface of exchange between fish and the environment, and they possess important biological and ecological functions. In the present study, the antioxidant activity (reducing power, total antioxidant capacity, and free ...
Fatemeh Gol Doost Bas, Narges Amrollahi Biuki, Soolmaz Soleimani, Morteza Yousefzadi   +3 more
doaj  

Rational Use of Herbal Products in Pediatric Patients Treated With Anticancer Drugs in the European Union

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The use of herbal medical preparation (HMP) is rising among pediatric oncology patients, often to manage treatment‐related symptoms. Their effectiveness remains uncertain, and the risk of herb–drug interactions is underestimated.
Orianne Mahot, Mathieu Corvaisier, Laurence Spiesser‐Robelet, Mylène Duplan, Isabelle Pellier, Delphine Bourneau‐Martin, Séverine Derbré   +6 more
wiley   +1 more source

Association Between Dinutuximab Beta Exposure and Post‐End‐of‐Treatment Survival in Neuroblastoma: A Weighted Patient‐Level Analysis of Three Clinical Studies

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives The association between exposure to dinutuximab beta (DB) and event‐free survival (EFS) or overall survival (OS) of neuroblastoma patients was assessed using data collected during three clinical trials (five cohorts). Methods A systematic review (March 2026) was conducted to identify relevant studies (prospective; registered DB ...
Przemysław Holko, Holger N. Lode, Alberto Garaventa, Carla Manzitti, Roberto Luksch, Dominique Valteau‐Couanet, Marion Gambart, John Anderson, Juliet Gray, Adela Canete, Lucas Moreno, Aleksandra Wieczorek, Cormac Owens, Shifra Ash, Isaac Yaniv, Genevieve Laureys, Hans Loibner, Katarzyna Śladowska, Ruth Ladenstein, Paweł Kawalec   +19 more
wiley   +1 more source

Evaluation of newly synthesized schiff base Pd(II) complexes for prostate cancer treatment through in vitro cytotoxicity and molecular mechanistic studies

Frontiers in Chemistry
IntroductionPalladium (II) complexes are promising anticancer agents with potential advantages over platinum drugs. This study aimed to synthesize and characterize three new Pd(II) complexes (2a–2c) with Schiff base ligands derived from salicylic acid ...
Damnjan Pantic, Damnjan Pantic, Nikola Mirkovic, Nikola Mirkovic, Tatjana Vulovic, Tatjana Vulovic, Danijela Jovanovic, Danijela Jovanovic, Stefan Jakovljevic, Stefan Jakovljevic, Petar Canovic, Milan Zaric, Radica Zivkovic Zaric, Radica Zivkovic Zaric, Marina Kostic, Jovana Dragojevic, Vera Divac, Ziko Milanovic, Kristina Milisavljevic, Kristina Milisavljevic, Marina Mitrovic, Ivanka Zelen   +21 more
doaj   +1 more source

Lymphocyte Cytotoxicity in vitro: Activation and Release of a Cytotoxic Factor [PDF]

Nature, 1968
WE have reported that cell contact per se is not sufficient to explain the rapid and dramatic in vitro destruction of target L cells observed when they are treated with immune lymphocytes or non-immune phytohaemagglutinin (PHA)-stimulated lymphocytes derived from various inbred mice1.
Granger, G A, Williams, T W
openaire   +4 more sources