Results 31 to 40 of about 709,234 (313)

Isolation, characterization, and encapsulation of a lupeol-rich fraction obtained from the hexanic extract of Coccoloba uvifera L. leaves

Exploration of Foods and Foodomics, 2023
Aim: This study aimed to isolate, characterize, and encapsulate a lupeol-rich fraction obtained from the hexanic extract of Coccoloba uvifera L. leaves to evaluate its potential use in nutraceutical or pharmaceutical applications.
Carla N. Cruz-Salas, Zoran Evtoski, Montserrat Calderón-Santoyo, José M. Lagarón, Cristina Prieto, Juan A. Ragazzo-Sánchez   +5 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Cytotoxicity of Printed Aligners: A Systematic Review

Dentistry Journal
Background/Objectives: The capability of printing aligners directly, eliminating the need for a dental model or thermoforming, represents a significant advancement in aligner therapy. This review aimed to assess the cytotoxicity of 3D-printed aligners to
Mauro Lorusso, Fariba Esperouz, Gabriele Di Carlo, Michele Tepedino, Rosa Esposito, Giovanni Pappalettera, Caterina Casavola, Lucio Lo Russo, Domenico Ciavarella   +8 more
doaj   +1 more source

Skin mucus of saltwater fish: a new source of antioxidant activity and cytotoxicity [PDF]

بوم‌شناسی آبزیان, 2022
Fish mucus layers are the main surface of exchange between fish and the environment, and they possess important biological and ecological functions. In the present study, the antioxidant activity (reducing power, total antioxidant capacity, and free ...
Fatemeh Gol Doost Bas, Narges Amrollahi Biuki, Soolmaz Soleimani, Morteza Yousefzadi   +3 more
doaj  

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Lymphocyte Cytotoxicity in vitro: Activation and Release of a Cytotoxic Factor [PDF]

Nature, 1968
WE have reported that cell contact per se is not sufficient to explain the rapid and dramatic in vitro destruction of target L cells observed when they are treated with immune lymphocytes or non-immune phytohaemagglutinin (PHA)-stimulated lymphocytes derived from various inbred mice1.
Granger, G A, Williams, T W
openaire   +4 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Evaluation of newly synthesized schiff base Pd(II) complexes for prostate cancer treatment through in vitro cytotoxicity and molecular mechanistic studies

Frontiers in Chemistry
IntroductionPalladium (II) complexes are promising anticancer agents with potential advantages over platinum drugs. This study aimed to synthesize and characterize three new Pd(II) complexes (2a–2c) with Schiff base ligands derived from salicylic acid ...
Damnjan Pantic, Damnjan Pantic, Nikola Mirkovic, Nikola Mirkovic, Tatjana Vulovic, Tatjana Vulovic, Danijela Jovanovic, Danijela Jovanovic, Stefan Jakovljevic, Stefan Jakovljevic, Petar Canovic, Milan Zaric, Radica Zivkovic Zaric, Radica Zivkovic Zaric, Marina Kostic, Jovana Dragojevic, Vera Divac, Ziko Milanovic, Kristina Milisavljevic, Kristina Milisavljevic, Marina Mitrovic, Ivanka Zelen   +21 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source