Results 41 to 50 of about 773,483 (256)
MoleculesThe aim of this case study was the evaluation of the selected metals’ concentration, potential toxic compound identification, cytotoxicity analysis, estimation of the airborne dust concentration, biodiversity, and number of microorganisms in the ...
Justyna Szulc +7 more
doaj +1 more source
Synthesis, Anticancer Evaluation and Molecular Docking studies of Novel Benzophenone based 1,2,3-Triazole Hybrids [PDF]
Journal of Chemistry LettersA series of novel benzophenone based1,2,3-triazole hybrids (8a-l) were synthesized. The biological screening of these compounds was performed on antibacterial, antioxidant, and cytotoxic activity (HT-1080, A-549 cell lines).Compounds 8d, 8h, and 8l are ...
Venkateswara Rao Battula +6 more
doaj +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Conversion of a Short Lipopeptoid into Longer Non-lipidated Repeat Peptoids with Improved Activity [PDF]
, 2021 The need for new antibiotics to treat antibiotic resistant bacteria has been a growing problem worldwide over the past several years. Bacteria are quickly developing modifications to render antibiotics useless due to overuse and misuse of medications ...
Tran, Mary Ngoc
core
, 2022 Type 1 diabetes in children is heralded by a preclinical phase defined by circulating autoantibodies to pancreatic islet antigens. How islet autoimmunity is initiated and then progresses to clinical diabetes remains poorly understood.
Esther Bandala-Sanchez (38946) +11 more
core +1 more source
MoleculesThe fruits of Cornus officinalis are used not only as a popular health food to tonify the liver and kidney, but also as staple materials to treat dementia and other age-related diseases. The pharmacological function of C.
Jinyi Zhang +5 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Cytotoxicity Definition, Identification, and Cytotoxic Compounds
, 2019 Life is a short process between mortality and immortality. In fact, immortality is not as interesting as imagined. Together with the transition from unicellular cells to multicellular organisms, cytotoxicity has a different meaning. While cytotoxicity in
İla, Hasan Basri, İstifli, Erman Salih
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Synthesis of ethers containing 1,3-dioxolane and gem-dichlorocyclopropane fragments
Тонкие химические технологии, 2021 Objectives. This study aimed to obtain ethers containing gem-dichlorocyclopropane and 1,3-dioxolane fragments and evaluate their cytotoxic properties against HEK293, SH-SY5Y, MCF-7, and A549 cell lines.Methods.
Sh. Sh. Dzhumaev +5 more
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