Results 11 to 20 of about 712,474 (313)

Fibril Fragmentation Enhances Amyloid Cytotoxicity [PDF]

, 2009
Fibrils associated with amyloid disease are molecular assemblies of key biological importance, yet how cells respond to the presence of amyloid remains unclear. Cellular responses may not only depend on the chemical composition or molecular properties of
Xue, Wei-Feng, Hellewell, Andrew L., Gosal, Walraj S., Hewitt, Eric W., Radford, Sheena E., Homans, Steve W.   +5 more
core   +1 more source

Role of surface charge and oxidative stress in cytotoxicity of organic monolayer-coated silicon nanoparticles towards macrophage NR8383 cells [PDF]

, 2010
Background - Surface charge and oxidative stress are often hypothesized to be important factors in cytotoxicity of nanoparticles. However, the role of these factors is not well understood.
de Haan, L.H.J., Nynke M Evers, Gerrit M Alink, Marcelis, A.T.M., Alink, G.M., Antonius TM Marcelis, Evers, N.M., Xue Jiang, Laura HJ de Haan, Rietjens, I.M.C.M., Zuilhof, H., Laura H. J. DE Haan, Ivonne MCM Rietjens, Jiang, X., Sourav Bhattacharjee, Antonius T. M. Marcelis, Han Zuilhof, Haan, L.H.J., de, Nynke M. Evers, Bhattacharjee, S., Ivonne M. C. M. Rietjens, Gerrit M. Alink   +21 more
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Mechanism of cytotoxicity of paraquat [PDF]

Environmental Health and Preventive Medicine, 2002
Acute paraquat poisoning seems to be very complex because many possible mechanisms of paraquat cytotoxicity have been reported. Some may not be the cause of paraquat poisoning but the result or an accompanying phenomenon of paraquat action. The mechanism critical for cell damage is still unknown.
FUKUSHIMA, Tetsuhito, TANAKA, Keiko, LIM, Heejin, MORIYAMA, Masaki   +3 more
openaire   +2 more sources

Effect of size, shape, and surface modification on cytotoxicity of gold nanoparticles to human Hep-2 and canine MDCK cells [PDF]

, 2012
There have been increasing interests in applying gold nanoparticles in biological research, drug delivery, and therapy. As the interaction of gold nanoparticles with cells relies on properties of nanoparticles, the cytotoxicity is complex and still under
Li, Wenqin, Xu, Dan, Chen, Yu, Zhang, Yinan, Yu, Jun   +4 more
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Essential oils in ocular pathology: an experimental study

Journal of Infection in Developing Countries, 2015
Introduction: The antimicrobial activity of essential oils (EOs) has been known for ages; in particular, the EOs of Melaleuca alternifolia, Thymus vulgaris, Mentha piperita, and Rosmarinus officinalis have been used for the treatment of fungal and ...
Sara Cannas, Donatella Usai, Antonio Pinna, Stefania Benvenuti, Roberta Tardugno, Matthew Donadu, Stefania Zanetti, Jayaraman Kaliamurthy, Paola Molicotti   +8 more
doaj   +1 more source

Cell Division, Cytotoxicity, and the Assays Used in the Detection of Cytotoxicity [PDF]

, 2019
Cell division is a phenomenon that is encountered in all cells in nature. While normal cell division results in proliferation in single-celled organisms, and development and repair in multicellular organisms, aberrant and untimely cell division results ...
İla, Hasan Basri, Hasan Basri Ila, Erman Salih Istifli, Mehmet Tahir Hüsunet, İstifli, Erman Salih, Hüsunet, Mehmet Tahir   +5 more
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Mangiferin induces cell death against rhabdomyosarcoma through sustained oxidative stress

Integrative Medicine Research, 2015
Background: Embryonic rhabdomyosarcoma (RD) is the most prevalent type of cancer among children. The present study aimed to investigate cell death induced by mangiferin in RD cells.
Vishwanadha Vijaya Padma, Palanisamy Kalaiselvi, Rangasamy Yuvaraj, M. Rabeeth   +3 more
doaj   +1 more source

Uptake and cytotoxicity of citrate-coated gold nanospheres : comparative studies on human endothelial and epithelial cells [PDF]

, 2012
The use of gold nanoparticles (AuNPs) for diagnostic applications and for drug and gene-delivery is currently under intensive investigation. For such applications, biocompatibility and the absence of cytotoxicity of AuNPs is essential. Although generally
C Kirkpatrick, Romero, Ignacio, Kirkpatrick, C. James, Weksler Babette B, Uboldi, Chiara, Gibson, Matthew I.; id_orcid, Gibson, Matthew, Kirkpatrick, C. J. (C. James), Weksler, Babette B., Freese, Christian, Unger, Ronald E., Romero Ignacio A, Kirkpatrick, James, C., Couraud, Pierre-Olivier, Kirkpatrick C, Gibson, Matthew I., Babette B Weksler, Weksler, Babette, Kirkpatrick, James,, Pierre-Olivier Couraud, Gibson Matthew I, Kirkpatrick, C. J., Couraud Pierre-Olivier, Unger Ronald E, Chiara Uboldi, Matthew I Gibson, Ignacio A Romero, Unger, Ronald, Freese Christian, Ronald E Unger, Uboldi Chiara, Romero, Ignacio A., Christian Freese   +32 more
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Determination of the cytotoxic effect of Prangos ferulacea (L.) Lindl. which grows naturally in the foothills of Bayburt Kop Mountain, on non-small lung cancer

Medicine Science, 2023
The genus Prangos has been used for centuries as an antibacterial and antidiabetic agent. In this study, Prangos ferulacea (L.) Lindl. species, which is frequently encountered in various regions of our country, especially in Northeast Anatolia, and known
Hamit Emre Kizil
doaj   +1 more source

Functionalization of osmium arene anticancer complexes with (poly)arginine : effect on cellular uptake, internalization, and cytotoxicity [PDF]

, 2011
Attaching peptides to metallodrugs may result in improved biological properties of the complexes. The potential use of cell penetrating peptides (CPPs) as cell delivery vectors is attractive, since directed cell uptake of (metallo)drugs remains a major ...
Rijt, Sabine H. van, Peter J. Sadler, Sadler, P. J., Hana Kostrhunova, Viktor Brabec, Brabec, V. (Viktor), Sabine H. van Rijt, Kostrhunova, Hana   +7 more
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