Optimization of the Hemolysis Assay for the Assessment of Cytotoxicity
International Journal of Molecular Sciences, 2023 In vitro determination of hemolytic properties is a common and important method for preliminary evaluation of cytotoxicity of chemicals, drugs, or any blood-contacting medical device or material.
Ingvill Pedersen Sæbø +4 more
semanticscholar +1 more source
Immunity, 2020 Neutrophils are expanded and abundant in cancer-bearing hosts. Under the influence of CXCR1 and CXCR2 chemokine receptor agonists and other chemotactic factors produced by tumors, neutrophils, and granulocytic myeloid-derived suppressor cells (MDSCs ...
Á. Teijeira +25 more
semanticscholar +1 more source
Investigation of the cytotoxicity of CCVD carbon nanotubes towards human umbilical vein endothelial cells [PDF]
, 2006 The cytotoxicity of different samples of carbon nanotubes synthesised by catalytic chemical vapour deposition was investigated towards human umbilical vein endothelial cells, using two cytotoxicity standard assays (neutral red assay for the cell ...
Baquey, Charles +4 more
core +2 more sources
Cytotoxic T cells are able to efficiently eliminate cancer cells by additive cytotoxicity
Nature Communications, 2021 Lethal hit delivery by cytotoxic T lymphocytes (CTL) towards B lymphoma cells occurs as a binary, “yes/no” process. In non-hematologic solid tumors, however, CTL often fail to kill target cells during 1:1 conjugation.
B. Weigelin +8 more
semanticscholar +1 more source
Characterization of Electronic Cigarette Aerosol and Its Induction of Oxidative Stress Response in Oral Keratinocytes. [PDF]
, 2016 In this study, we have generated and characterized Electronic Cigarette (EC) aerosols using a combination of advanced technologies. In the gas phase, the particle number concentration (PNC) of EC aerosols was found to be positively correlated with puff ...
Chang, Chong Hyun +8 more
core +6 more sources
Complement activation induces excessive T cell cytotoxicity in severe COVID-19
medRxiv, 2021 Severe COVID-19 is linked to both dysfunctional immune response and unrestrained immunopathogenesis, and it remains unclear if T cells also contribute to disease pathology.
Philipp Georg +57 more
semanticscholar +1 more source
Enhancing anticancer cytotoxicity through bimodal drug delivery from ultrasmall Zr MOF nanoparticles [PDF]
, 2018 Dual delivery of dichloroacetate and 5-fluorouracil from Zr MOFs into cancer cells is found to enhance in vitro cytotoxicity. Tuning particle size and, more significantly, surface chemistry, further improves cytotoxicity by promoting caveolae-mediated ...
Abánades Lázaro, Isabel +2 more
core +1 more source
Photodegradation of carbon dots cause cytotoxicity
Nature Communications, 2021 Carbon dots (CDs) are photoluminescent nanomaterials with wide-ranging applications. Despite their photoactivity, it remains unknown whether CDs degrade under illumination and whether such photodegradation poses any cytotoxic effects.
Yuefang Liu +8 more
semanticscholar +1 more source
TMEM97 and PGRMC1 do not mediate sigma-2 ligand-induced cell death [PDF]
, 2019 Sigma-2 receptors have been implicated in both tumor proliferation and neurodegenerative diseases. Recently the sigma-2 receptor was identified as transmembrane protein 97 (TMEM97).
Hawkins, William G. +9 more
core +3 more sources
Probing the Cytotoxicity Of Semiconductor Quantum Dots.
Nano letters (Print), 2004 With their bright, photostable fluorescence, semiconductor quantum dots show promise as alternatives to organic dyes for biological labeling. Questions about their potential cytotoxicity, however, remain unanswered.
A. M. Derfus, W. Chan, S. Bhatia
semanticscholar +1 more source