Epitope-level analysis of cross-reactive human HLA antibodies against genetically modified swine leukocyte antigens in xenotransplantation [PDF]
Frontiers in ImmunologyIntroductionXenotransplantation using genetically modified pigs is a promising solution to organ shortages, particularly for highly sensitized patients with broad anti-HLA sensitization who lack compatible allografts.
Sang-Ik Cho +8 more
doaj +2 more sources
Anti-inflammatory effect of amalgam on periapical lesion cells in culture [PDF]
Vojnosanitetski Pregled, 2021 Background/Aim. Amalgam has been used for years in dentistry, but the controversy on its adverse effects, both on local oral/dental tissues and systemic health, still exists.
Eraković Mile +6 more
doaj +1 more source
Cytotoxic immunological synapses [PDF]
Immunological Reviews, 2010 Summary: One of the most fundamental activities of the adaptive immune system is to kill infected cells and tumor cells. Two distinct pathways mediate this process, both of which are facilitated by a cytotoxic immunological synapse. While traditionally thought of as innate immune cells, natural killer (NK) cells are now appreciated to have the ...
Dustin, M, Long, E
openaire +3 more sources
Increased Natural Killer Cell Activation in HIV-Infected Immunologic Non-Responders Correlates with CD4+ T Cell Recovery after Antiretroviral Therapy and Viral Suppression. [PDF]
PLoS ONE, 2017 The role of natural killer (NK) cell function in HIV disease especially in the setting of long-term antiretroviral therapy (ART) and viral suppression is not fully understood.
Zhenwu Luo +9 more
doaj +1 more source
Phasing out the pre-transplant cytotoxicity crossmatch: Are we missing something?
Brazilian Journal of Nephrology, 2021 Introduction: The anti-human globulin-enhanced complement-dependent cytotoxicity crossmatch (AHG-CDCXM) assay has been used to assess the presence of donor-specific antibodies (DSA) in recipient’s serum before kidney transplantation. The flow cytometric
Jamile Abud +6 more
doaj +2 more sources
Immunologic difference between hypersensitivity to mosquito bite and hemophagocytic lymphohistiocytosis associated with Epstein-Barr virus infection. [PDF]
PLoS ONE, 2013 Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening, virus-triggered immune disease. Hypersensitivity to mosquito bite (HMB), a presentation of Chronic Active Epstein-Barr Virus infection (CAEBV), may progress to HLH.
Wen-I Lee +11 more
doaj +1 more source
Genetic, immunological, and cytotoxic comparisons of Legionella proteolytic activities [PDF]
Infection and Immunity, 1989 Several strains of Legionella pneumophila and other species of Legionella with proteolytic activities were compared by assays, including Southern hybridizations and Western immunoblots, to determine their proteolytic, hemolytic, and cytotoxic activities. Only proteases from strains of L.
F D, Quinn, M G, Keen, L S, Tompkins
openaire +2 more sources
Frontiers in Dentistry, 2021 Objectives: Toothpastes and mouthwashes contain chemicals that may be harmful to oral tissues. This study assessed the cytotoxicity and antibacterial activity of toothpastes and compare the Iranian and foreign toothpastes and mouthwashes available in the
Zahra Shahidi +7 more
doaj +1 more source
UV Photoprotection, Cytotoxicity and Immunology Capacity of Red Algae Extracts [PDF]
Molecules, 2019 This study was designed to evaluate the potential use of algal extracts in cosmeceuticals, including factors related to biosecurity. The aqueous crude extracts of Hydropuntia cornea and Gracilariopsis longissima showed a good photoprotective capacity (Sun Protection Factor, SPF) due to, among other reasons, the presence of five types of mycosporine ...
Félix Álvarez-Gómez +4 more
openaire +3 more sources
An Inhibitory Role for Human CD96 Endodomain in T Cell Anti-Tumor Responses
Cells, 2023 Immune checkpoint blockade (ICB) therapy involves the inhibition of immune checkpoint regulators which reverses their limitation of T cell anti-tumor responses and results in long-lasting tumor regression. However, poor clinical response or tumor relapse
Chelsia Qiuxia Wang +5 more
doaj +1 more source