Results 1 to 10 of about 905,093 (362)

Cytotoxic immunological synapses [PDF]

Immunological Reviews, 2010
Summary:  One of the most fundamental activities of the adaptive immune system is to kill infected cells and tumor cells. Two distinct pathways mediate this process, both of which are facilitated by a cytotoxic immunological synapse. While traditionally thought of as innate immune cells, natural killer (NK) cells are now appreciated to have the ...
Dustin, M, Long, E
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Genetic, immunological, and cytotoxic comparisons of Legionella proteolytic activities [PDF]

Infection and Immunity, 1989
Several strains of Legionella pneumophila and other species of Legionella with proteolytic activities were compared by assays, including Southern hybridizations and Western immunoblots, to determine their proteolytic, hemolytic, and cytotoxic activities. Only proteases from strains of L.
F D Quinn, Lucy S. Tompkins, M G Keen
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UV Photoprotection, Cytotoxicity and Immunology Capacity of Red Algae Extracts [PDF]

Molecules, 2019
This study was designed to evaluate the potential use of algal extracts in cosmeceuticals, including factors related to biosecurity. The aqueous crude extracts of Hydropuntia cornea and Gracilariopsis longissima showed a good photoprotective capacity (Sun Protection Factor, SPF) due to, among other reasons, the presence of five types of mycosporine ...
Félix Álvarez-Gómez, Nathalie Korbee, Virginia Casas-Arrojo, Roberto T. Abdala-Díaz, Félix L. Figueroa   +4 more
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Cytotoxic and Immunologic Effects of Methotrexate in Psoriasis

Journal of Investigative Dermatology, 1990
Based on recent experience that Cyclosporin A, an immunosuppressive drug, produces marked improvement in psoriasis, possible immunomodulatory activities of methotrexate (MTX) have been reviewed to look for alternate mechanisms of MTX action in psoriasis. It is generally considered that the therapeutic results of MTX in psoriasis are related to a direct
Edward W. B. Jeffes, Gerald D. Weinstein, Jerry L. McCullough   +2 more
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In vitro bio-immunological and cytotoxicity studies of poly(2-oxazolines) [PDF]

Journal of Materials Science: Materials in Medicine, 2011
Poly(2-oxazolines) with varying alkyl chain lengths (e.g., methyl, ethyl, aryl) and molar masses have been tested for cell cytotoxicity in vitro. A standard 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay was used for the estimation of cell viability.
Zuzana Kroneková, Lucia Paulovičová, Jozef Lustoň, Juraj Kronek, Barbara Mendrek, Ema Paulovičová   +5 more
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Altered distribution of mucosal NK cells during HIV infection. [PDF]

, 2012
The human gut mucosa is a major site of human immunodeficiency virus (HIV) infection and infection-associated pathogenesis. Increasing evidence shows that natural killer (NK) cells have an important role in control of HIV infection, but the mechanism(s ...
Alter, G, Berger, CT, Carrington, M, Deeks, SG, Diefenbach, T, Dugast, A-S, Estes, JD, Ghebremichael, M, Hunt, PW, Kwon, D, Liu, Q, Martin, JN, Sciaranghella, G, Sips, M   +13 more
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Cx43-Gap Junctions Accumulate at the Cytotoxic Immunological Synapse Enabling Cytotoxic T Lymphocyte Melanoma Cell Killing [PDF]

International Journal of Molecular Sciences, 2019
Upon tumor antigen recognition, cytotoxic T lymphocytes (CTLs) and target cells form specialized supramolecular structures, called cytotoxic immunological synapses, which are required for polarized delivery of cytotoxic granules. In previous reports, we described the accumulation of connexin 43 (Cx43)-formed gap junctions (GJs) at natural killer (NK ...
Francisca Hofmann, Mariela Navarrete, Javiera Álvarez, Israel Guerrero, María Alejandra Gleisner, Andrés Tittarelli, Flavio Salazar-Onfray   +6 more
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DR-bearing T lymphocytes in thoracic duct lymph [PDF]

, 1981
T cells having DR antigens were shown to be present in high numbers in the thoracic duct lymph of patients undergoing long-term drainage. As drainage progresses the proportion of T DR cells in the lymph increases to levels as high as 70% at 6 weeks ...
Abo, Albrechtson, Billing, Boyle, Colombani, Evans, Foon, Franksson, Fu, Greaves, H. Takahashi, J.C. Cicciarelli, Johnson, Kaplan, Machleder, Matell, Medawar, P.I. Terasaki, R. Billing, Starzl, Starzl, Suciu-Foca, T. Starzl, T. Yamaguchi, Terasaki, Y. Iwaki   +25 more
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Immunological Changes after Cancer Treatment and Participation in an Exercise Program [PDF]

, 2003
Purpose: The purpose of this investigation was to evaluate the impact of undertaking peripheral blood stem cell transplantation (PBST) on T-cell number and function, and to determine the role of a mixed type, moderate intensity exercise program in ...
Andrykowski, Birk, Brenner, Brittenden, Chess, Cohen, Dimeo, Hannet, Henon, Keast, Laperriere, Laperriere, Molrine, Mosmann, Nieman, Nordon, Peters, Pyne, Rigsby, Shephard, Shevde, Spitzer, Talmadge, Uh, Weidemann, Winningham, Woods, Young-Moo   +27 more
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Phototesting and photoprotection in LE [PDF]

, 1997
Photosensitivity and induction of skin lesions following UV radiation is a common problem of patients with cutaneous and systemic forms of lupus erythematosus.
Cazenave A., Dubois EL, Fisher AA, Freund H., Fuhs E., G. Messer, Garzon R., Gilliam JN, Hölzle E., Jesionek A., Kind P., Kind P., M. Walchner, P. Kind, Tuffanelli DL, Wallace DJ   +15 more
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