Epitope-level analysis of cross-reactive human HLA antibodies against genetically modified swine leukocyte antigens in xenotransplantation [PDF]
Frontiers in ImmunologyIntroductionXenotransplantation using genetically modified pigs is a promising solution to organ shortages, particularly for highly sensitized patients with broad anti-HLA sensitization who lack compatible allografts.
Sang-Ik Cho +8 more
doaj +2 more sources
Anti-inflammatory effect of amalgam on periapical lesion cells in culture [PDF]
Vojnosanitetski Pregled, 2021 Background/Aim. Amalgam has been used for years in dentistry, but the controversy on its adverse effects, both on local oral/dental tissues and systemic health, still exists.
Eraković Mile +6 more
doaj +1 more source
Increased Natural Killer Cell Activation in HIV-Infected Immunologic Non-Responders Correlates with CD4+ T Cell Recovery after Antiretroviral Therapy and Viral Suppression. [PDF]
PLoS ONE, 2017 The role of natural killer (NK) cell function in HIV disease especially in the setting of long-term antiretroviral therapy (ART) and viral suppression is not fully understood.
Zhenwu Luo +9 more
doaj +1 more source
Phasing out the pre-transplant cytotoxicity crossmatch: Are we missing something?
Brazilian Journal of Nephrology, 2021 Introduction: The anti-human globulin-enhanced complement-dependent cytotoxicity crossmatch (AHG-CDCXM) assay has been used to assess the presence of donor-specific antibodies (DSA) in recipient’s serum before kidney transplantation. The flow cytometric
Jamile Abud +6 more
doaj +2 more sources
Immunologic difference between hypersensitivity to mosquito bite and hemophagocytic lymphohistiocytosis associated with Epstein-Barr virus infection. [PDF]
PLoS ONE, 2013 Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening, virus-triggered immune disease. Hypersensitivity to mosquito bite (HMB), a presentation of Chronic Active Epstein-Barr Virus infection (CAEBV), may progress to HLH.
Wen-I Lee +11 more
doaj +1 more source
An Inhibitory Role for Human CD96 Endodomain in T Cell Anti-Tumor Responses
Cells, 2023 Immune checkpoint blockade (ICB) therapy involves the inhibition of immune checkpoint regulators which reverses their limitation of T cell anti-tumor responses and results in long-lasting tumor regression. However, poor clinical response or tumor relapse
Chelsia Qiuxia Wang +5 more
doaj +1 more source
Frontiers in Dentistry, 2021 Objectives: Toothpastes and mouthwashes contain chemicals that may be harmful to oral tissues. This study assessed the cytotoxicity and antibacterial activity of toothpastes and compare the Iranian and foreign toothpastes and mouthwashes available in the
Zahra Shahidi +7 more
doaj +1 more source
Altered distribution of mucosal NK cells during HIV infection. [PDF]
, 2012 The human gut mucosa is a major site of human immunodeficiency virus (HIV) infection and infection-associated pathogenesis. Increasing evidence shows that natural killer (NK) cells have an important role in control of HIV infection, but the mechanism(s ...
Alter, G +13 more
core +2 more sources
Cytotoxicity and genotoxicity of calcium silicate-based cements on an osteoblast lineage
Brazilian Oral Research, 2016 Several calcium silicate-based biomaterials have been developed in recent years, in addition to Mineral Trioxide Aggregate (MTA). The aim of this study was to evaluate the cytotoxicity, genotoxicity and apoptosis/necrosis in human osteoblast cells (SAOS ...
Ana Lívia GOMES-CORNÉLIO +7 more
doaj +1 more source
Assessment of intracanal medications cytotoxicity on L929 fibroblast cells
Bioscience Journal, 2016 This study aimed to evaluate the cytotoxicity of intracanal medications on L929 fibroblast cells at different periods of observation. The following experimental groups were studied: calcium hydroxide with camphorated paramonochlorophenol and glycerin ...
Michelle de Paula Farias +6 more
doaj +3 more sources