Results 161 to 170 of about 906,600 (363)

Engineering Topographical Cues to Enhance Neural Regeneration in Spinal Cord Injury: Overcoming Challenges and Advancing Therapies

Advanced Functional Materials, EarlyView.
Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu, Fenghui Wang, Joshua Stein, Siqiao Wang, Pengfei Jiang, Letao Yang, Liming Cheng, Ki‐Bum Lee   +7 more
wiley   +1 more source

Differences in Proinflammatory Cytokines and Monocyte Subtypes in Older as Compared With Younger Kidney Transplant Recipients. [PDF]

, 2018
Background:The number of elderly patients with end-stage kidney disease requiring kidney transplantation continues to grow. Evaluation of healthy older adults has revealed proinflammatory changes in the immune system, which are posited to contribute to ...
Abdalla, Basmah, Bunnapradist, Suphamai, Danovitch, Gabriel, Groysberg, Victoria, Korin, Yael, Liang, Emily C, Lum, Erik, Pham, Phuong-Thu, Reed, Elaine F, Rossetti, Maura, Schaenman, Joanna, Sidwell, Tiffany, Sunga, Gema, Vangala, Sitaram   +13 more
core   +1 more source

A morphologic and immunologic study of the large granular lymphocyte in neutropenia with T lymphocytosis.

Blood, 1984
We report four patients with expansion of a unique population of lymphocytes that is consistently associated with neutropenia. Two patients also had rheumatoid arthritis and autoantibodies. The lymphocytes contained many cytoplasmic azurophilic granules,
W. Chan, I. Check, C. Schick, R. Brynes, J. Kateley, E. Winton   +5 more
semanticscholar   +1 more source

3D Bioprinted Head and Neck Squamous Cell Carcinoma (HNSCC) Model Using Tunicate Derived Nanocellulose (NC) Bioink

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
A 3D bioprinted HNSCC model for use in anti‐cancer drug testing is established in proof‐of‐concept. The innovative tunicate‐derived nanocellulose hydrogel proved to be a viable alternative to gelatin‐based hydrogel, offering improved bioprintability for HNSCC model establishment.
Alexya Azhakesan, Johann Kern, Ankit Mishra, Christine Selhuber‐Unkel, Annette Affolter, Paul Gatenholm, Nicole Rotter, Karen Bieback   +7 more
wiley   +1 more source

The Biologic Response to Polyetheretherketone (PEEK) Wear Particles in Total Joint Replacement: A Systematic Review [PDF]

, 2016
Background: Polyetheretherketone (PEEK) and its composites are polymers resistant to fatigue strain, radiologically transparent, and have mechanical properties suitable for a range of orthopaedic applications.
Amstutz, Bladen, Holt, Ingram, Kabir, Latif, Matthews, Pace, Skinner, Wright   +9 more
core   +1 more source

An in vitro method for study of human lymphocyte cytotoxicity against mumps-virus-infected target cells.

Journal of Immunology, 1975
A chromium release assay was used to study lymphocyte-mediated cytotoxicity against mumps virus-infected target cells in vitro. Purified lmyphocytes from randomly selected donors killed significantly more virus-infected Vero cells than non-infected cells.
T. Andersson, V. Stejskal, B. Harfast
semanticscholar   +1 more source

Salt‐Compact Albumin as a New Pure Protein‐based Biomaterials: From Design to In Vivo Studies

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
A new class of materials built entirely of native albumin protein is designed using a simple protocol based on salt‐assisted compaction, breaking with current crosslinking strategies. This green process leads, surprisingly, to water‐insoluble handable materials with high preservation of their native protein structures and Young's modulus close to that ...
Eya Aloui, Jordan Beurton, Claire Medemblik, Ludivine Hugoni, Igor Clarot, Ariane Boudier, Youri Arntz, Marcella De Giorgi, Jérôme Combet, Guillaume Fleith, Eric Mathieu, Naji Kharouf, Leyla Kocgozlu, Benoît Heinrich, Damien Favier, Michael Brender, Fouzia Boulmedais, Pierre Schaaf, Benoît Frisch, Philippe Lavalle   +19 more
wiley   +1 more source

Effects of space structure and combination therapies on phenotypic heterogeneity and drug resistance in solid tumors [PDF]

arXiv, 2013
Histopathological evidence supports the idea that the emergence of phenotypic heterogeneity and resistance to cytotoxic drugs can be considered as a process of adaptation, or evolution, in tumor cell populations. In this framework, can we explain intra-tumor heterogeneity in terms of cell adaptation to local conditions?
arxiv  

The Three R\u27s of Delayed Hypersensitivity [PDF]

, 1974
Delayed hypersensitivity is one of several immune responses initiated by thymus-derived (T) lymphocytes. The mononuclear infiltrate of delayed hypersensitivity is a collaborative phenomenon between T lymphocytes and monocytes.
Horwitz, David
core   +1 more source

Bioengineering a Patient‐Derived Vascularized Lung Tumor‐on‐Chip Model to Decipher Immunomodulation by the Endothelium

Advanced Healthcare Materials, EarlyView.
Most in vitro cancer models lack cellular diversity, functional complexity, and clinical relevance. This work highlights the generation of an innovative dynamic tetraculture with autologous patient‐derived cells within a vascularized tumor‐on‐chip, as well as the recapitulation of endothelial anergy features induced by the tumor microenvironment ...
Christine Lansche, Ségolène Ladaigue, Giacomo Gropplero, Nicolas Zimmermann, Martin Nurmik, Irina Veith, Manh‐Louis Nguyen, Solenn Brosseau, Nicolas Poté, Pierre Mordant, Arnaud Roussel, Fathia Mami‐Chouaib, Fatima Mechta‐Grigoriou, Gérard Zalcman, Fabrice Soncin, Stéphanie Descroix, Maria Carla Parrini   +16 more
wiley   +1 more source