Results 171 to 180 of about 268,604 (303)

Xenotransplantation Literature Update: January-June 2026. [PDF]

Xenotransplantation
Shirini K, Ladowski JM, Harsh N, Meier RPH.   +3 more
europepmc   +1 more source

Optimized Lipid Nanoparticles with Tail‐Modified Ionizable Lipids for Safer mRNA Delivery

Advanced Science, EarlyView.
Systematic engineering of hydrophobic tail architecture in vitamin B5‐derived ionizable lipids establishes a comprehensive structure–activity relationship framework for mRNA delivery. Combined lipidtail and formulation optimization identifies TM1‐OPT3‐C, a lipid nanoparticle platform that improves efficacy–safety balance through efficient mRNA delivery,
Seo‐Hyeon Bae, Jisun Lee, Jae‐Hun Ahn, Hosam Choi, Huijeong Choi, Jungmin Kim, Minho Kang, Ho Rim Oh, So Hyun Park, Eun Young Oh, Sanghyuk Jeon, Yeeun Lee, Yu‐Sun Lee, Na‐Young Lee, Hee‐Jin Bae, Jina Kwak, Jooil Kim, Nakyung Lee, Beomsun Kang, Ji‐Hye Kim, Eunsaem Song, Daesub Song, Hyunho Yoon, Sang‐Myeong Lee, Hyewon Youn, Kiyoun Lee, Byeong‐Cheol Kang, Jae‐Hwan Nam   +27 more
wiley   +1 more source

What's Hot and What's New in Xenotransplantation From the Young Investigator Committee of the IXA-Basic and Translational Science. [PDF]

Xenotransplantation
Goerlich CE, Salvaris EJ, Fischer K, Citro A, Giarraputo A, Ladowski J, Mazancourt ES, Wang L, Eisenson D, Connolly MR, Stern J, Longchamp A, Meier RPH.   +12 more
europepmc   +1 more source

Dual Blockade of LILRB1 and LILRB2 Enhances Antiviral Immune Responses in SIV Infection

Advanced Science, EarlyView.
Dual LILRB1/B2 blockade with mac20G10 reshapes myeloid activation during acute SIV infection by targeting LILRB1 and LILRB2 on myeloid cells. This treatment enhances CD80 expression on selected myeloid subsets and increases plasma IFN‐λ, IL‐8, and IL‐1RA.
Florian Meurisse, Sixtine Coindre, Anne Wijkhuisen, Romain Marlin, Laure Fournier Le Ray, Juliette Pons, Melyssa Yaugel‐Novoa, Véronique Avettand‐Fenoel, Laurent Abi‐Rached, Anne‐Sophie Gallouet, Francis Relouzat, Mael Gourves, Asier Saez‐Cirion, Hisashi Arase, Gerard Zurawski, Sandra Zurawski, Nathalie Dereuddre‐Bosquet, Roger Le Grand, Stéphanie Simon, Olivier Lambotte, Benoit Favier   +20 more
wiley   +1 more source

Brain-dead humans as preclinical reference models for xenotransfusion: bridging nonhuman primates and clinical applications through <i>in vitro</i> evaluation. [PDF]

Front Physiol
Li T, Li J, Jin S, Liu L, Hara H, Gan H, Wang Y, Zhang Y, He S, Zhao T, Pan D, Jiang H, Wang Y.   +12 more
europepmc   +1 more source

Neuron‐Targeted Exosomal Delivery of siRNA Against RIPK3 Slows Neurodegenerative Progression in Alzheimer's Disease

Advanced Science, EarlyView.
Engineered exosomal siRNA delivery platform enables systemic, neuron‐targeted RNA transport across the blood–brain barrier. Surface functionalization with rabies virus glycoprotein‐derived peptide facilitates receptor‐mediated transcytosis, achieving efficient cytosolic delivery and robust gene silencing. Targeting RIPK3 suppresses necroptosis, reduces
Chi Zhang, Jiaqi Zhang, Yuzhi Wang, Yaodong Wang, Peng Lin, Yanling Wang, Zixuan Tang, Jintai Yu, Qin Zhou, Feiyun Cui   +9 more
wiley   +1 more source

Obinutuzumab after anti-rituximab antibody-associated treatment failure in membranous nephropathy: a case report. [PDF]

Front Immunol
Guo J, Zhong A, Wu D, Liu Y, Chen Y, Xu Y, Xu R, Wan Q.   +7 more
europepmc   +1 more source

Targeted β‐Glucan‐Veiled Oral Apremilast Nanotherapy Modulates Key Dysbiosis‐Associated Gut Microbiota and Alleviates Ulcerative Colitis‐Associated Anxiety, Depression, and Neuropsychiatric Behaviors

Advanced Science, EarlyView.
This study introduces β‐glucan‐shielded apremilast laden nanomicelles that withstand gastrointestinal degradation, selectively accumulate in inflamed colon tissue, and modulate the microbiota–gut–brain axis. The formulation restores barrier integrity, reduces systemic and neuroinflammation, and improves anxiety‐ and depression‐like behaviors in colitis
Chandrashekhar Jori, Ahmed Shaney Rehman, Taruna Lamba, Anas Ahmad, Jattin Kumar, Aneesh Ali, Ajesh Joshi, Ashraf Ali, Suhel Parvez, Javed N. Agrewala, Rehan Khan   +10 more
wiley   +1 more source

Comprehensive Evaluation of Safety, Functional Properties, and Immunomodulatory Activity of 19 Probiotic Strains Approved by the Ministry of Food and Drug Safety (MFDS). [PDF]

J Microbiol Biotechnol
Kim Y, Lee S, Kim S, Jung M, Jung J, Lee JH, Bai J.   +6 more
europepmc   +1 more source

[Interferon, immunologic recognition and cytotoxicity of lymphocytes].

Voprosy virusologii, 1974
G Ia, Svet-Moldavskiĭ, B M, Nemirovskaia, T V, Osipova, E G, Slavina, S N, Zinzar   +4 more
openaire   +1 more source