Results 201 to 210 of about 33,742 (266)

Reprogramming the Immune Landscape of Inflammatory Breast Cancer

Advanced Science, EarlyView.
Inflammatory breast cancer is the most lethal subtype of breast cancer and is characterized by an immunosuppressive tumor microenvironment (TME) driven by a complex network of immune cells and inflammatory cytokines, contributing to its aggressiveness and treatment challenges. Immune checkpoint inhibitors, either alone or in combination, show potential
Verena Martinez‐Rodriguez, Suguru Ogata, Xiaoping Wang, Naoto T. Ueno   +3 more
wiley   +1 more source

Allele-specific KRAS signaling: shaping tumor immunity and therapeutic response in lung adenocarcinoma. [PDF]

Signal Transduct Target Ther
Papavassiliou KA, Stravopodis DJ, Papavassiliou AG.   +2 more
europepmc   +1 more source

[Natural cytotoxic cells (NK) and their role in the immunological control of neoplasms].

Postepy higieny i medycyny doswiadczalnej, 1982
Z M, Rupniewska, M B, Adamczyk
openaire   +1 more source

Senescent Cell Derived Artificial Vesicle‐Based Senolytic Sonovaccine Platform with Augmented Lymph Node Delivery and Antigen Cross‐Presentation Efficacy

Advanced Science, EarlyView.
A senolytic sonovaccine platform (SenoVac) is developed, in which senescent cell‐derived vesicles serve as broad senescent cell antigen reservior. The “2‐step” click chemistry strategy for effective lymph node delivery, and ultrasound‐triggered endosomal escape to boost cross‐presentation, ensures efficient senescent cell clearance and disease ...
Liang Zhang, Yubo Lai, Jia Wang, Lingling Liu, Jieyuan An, Mi Qu, Yuan Liang, Bijun Tan, Guodong Yang, Xuekang Yang, Lijun Yuan   +10 more
wiley   +1 more source

BaEV-pseudotyped lentiviral vectors enable stable CAR expression and cytotoxic function in NK cells. [PDF]

PLoS One
Park M, Lim Y, Jo Y, Jo DH, Kim SK, Kim HY, Lee SH, Lee M, Cho D.   +8 more
europepmc   +1 more source

Bandgap‐Engineered PtxTey:Ag2Te Composite Quantum Dots Enable Programmable NIR‐II Imaging and Photothermal‐Immune Synergistic Therapy

Advanced Science, EarlyView.
A bandgap‐engineered PtxTey:Ag2Te quantum dot platform enables tunable NIR‐IIb emission for deep‐tissue imaging and mild photothermal therapy. Conjugation with αPD‐L1 confers dual tumor targeting and real‐time monitoring of PD‐L1 dynamics. Mild photothermal modulation induces immune reprogramming, enhancing checkpoint blockade efficacy and achieving ...
Jing Liu, Rui Xu, Quan Wu, Tian‐Xin Xiao, Lai‐Xi Zhao, Lei Sun, Ya‐Wen Zheng, Liang Dong, Zhi‐Quan Tian, Haibo Wang   +9 more
wiley   +1 more source

SSR4 sustains Tertiary Lymphoid Structures by Regulation Quality Control of N‐linked Glycosylation During B‐cell Differentiation Into Plasmacyte in Colorectal Cancer

Advanced Science, EarlyView.
SSR4, a TRAP component induced in B cells, governs BAFFR N‐glycosylation via DDOST to sustain NF‐κB signaling, B‐cell differentiation, and TLS maturation. Its loss impairs anti‐tumor immunity, while overexpression improves antibody glycosylation and ADCC, revealing a critical regulator for cancer immunotherapy.
Wei Zhao, Youcai Zhao, Haiyang Li, Bowen Yang, Siyan Lu, Xueting Fu, Caixia Zhang, Yirong Chen, Xiaofeng Bian, Xinghua Ma, Xiaobing Yang, Bin Wang, Yuan Fang, Lulu Yang, Yelin Zhao, Shuli Zhao   +15 more
wiley   +1 more source

Efficacy and safety of zuberitamab in the treatment of primary membranous nephropathy: an observational study. [PDF]

Front Immunol
Zong L, Wang S, Zhao K, Lv FY, Qian SK, Yang XD.   +5 more
europepmc   +1 more source

Data-driven computational modeling of CAR-T cell function. [PDF]

Front Immunol
Shah V, Womack JA, Palen K, Johnson BD, Hematti P, Kearl TJ, Shah NN, Terhune SS, Dash RK.   +8 more
europepmc   +1 more source

B cells in acquired aplastic anemia and the exploratory role of rituximab: considerations in pediatric and female patients. [PDF]

Front Immunol
Pan L, Lin J, Zhou X, Zeng Y, Huang C, Fu Y.   +5 more
europepmc   +1 more source