Results 291 to 300 of about 937,918 (334)
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Human tumor necrosis factor potentiates human interleukin 1-mediated rat pancreatic beta-cell cytotoxicity.

Journal of Immunology, 1987
Previous studies have established that the cytokine interleukin 1 (IL-1) is selectively cytotoxic for isolated human and rat pancreatic beta-cells.
T. Mandrup-Poulsen   +3 more
semanticscholar   +1 more source

Importance of Immunologically Competent Cells in Contact-induced Cytotoxicity

Nature, 1970
IT is not yet clear whether the cytotoxicity observed when target cells and allogeneic lymphoid cells are cultured together in vitro1,2 is mediated by an immunological mechanism. Cell death has been attributed to contact with the antigenically or structurally incompatible lymphocyte cell surface rather than by any conventional immunological reaction2,3.
openaire   +2 more sources

Immunologically Mediated Cytotoxicity against Human Eye Muscle Cells in Graves’ Ophthalmopathy*

The Journal of Clinical Endocrinology & Metabolism, 1986
The possible roles of antibody-mediated complement-dependent cytotoxicity (AMC), antibody-dependent killer (K) cell-mediated cytotoxicity (ADCC), and spontaneous, natural killer (NK) cell-mediated cytotoxicity (NKC) against human eye muscle cells in the pathogenesis of Graves' ophthalmopathy were investigated, using as targets human eye muscle cells ...
P W, Wang   +5 more
openaire   +2 more sources

Antibody-Mediated Complement-Dependent Cytotoxicity in Immunologically Induced Experimental Colon Disease

International Archives of Allergy and Immunology, 1980
Rabbits immunized with a saline extract of intestinal tissue in complete Freund’s adjuvant produce antibody which mediates complement-dependent cytotoxicity for colon epithelial cells <i>in vitro</i>. The presence of this antibody did not correlate with histologic alterations of the colon in the immunized rabbits.
B S, Rabin, E, Herrington
openaire   +2 more sources

[Endometriosis and discouragement of immunology cytotoxic characteristics].

Ginecologia y obstetricia de Mexico, 2004
To determine the immunology kind of response Th1 (cytotoxic) or Th2 (humoral) prevailing at peripheral and peritoneal environment at endometriosis women (ENW).Observational, transverse, analytical, retrospective, cases and controls.Cooperative and cytotoxic lymphocytes obtained from peritoneal fluid (PF) and peripheral blood (PB) were used to determine
César Angel, Hernández Guerrero   +5 more
openaire   +1 more source

Studies on the mechanism of antibody-dependent polymorphonuclear leukocyte-mediated cytotoxicity.

Journal of Immunology, 1977
Human polymorphonuclear leukocytes (PMN) were cytotoxic to mammalian tumor cells (LSTRA) in the presence of anti-LSTRA serum as determined by a 51Cr release assay.
R. Clark, S. Klebanoff
semanticscholar   +1 more source

HIV-specific cytotoxic T-lymphocyte activity in immunologically normal HIV-infected persons

AIDS, 1998
CD8+ T-cell counts usually increase soon after infection with HIV, whereas CD4+ cell counts decrease. The result of these changes in T-cell subpopulation subsets in most HIV-infected subjects is inversion of the CD4 : CD8 ratio from greater than 1.0 typical of uninfected persons to less than 1.0 after infection.Six HIV-infected individuals were ...
N F, Bernard   +5 more
openaire   +2 more sources

Cytotoxicity and Immunological Response of Gold and Silver Nanoparticles of Different Sizes

Small, 2009
AbstractThe immunological response of macrophages to physically produced pure Au and Ag nanoparticles (NPs) (in three different sizes) is investigated in vitro. The treatment of either type of NP at ≥10 ppm dramatically decreases the population and increases the size of the macrophages.
Hung-Jen, Yen   +2 more
openaire   +2 more sources

Failure of infiltrating precursor cytotoxic T cells to acquire direct cytotoxic function in immunologically privileged sites.

The Journal of Immunology, 1990
Abstract Minor H incompatible P815 tumor cells inoculated into the anterior chamber (AC) of the eyes of BALB/c mice grow progressively, revealing this to be an immunologically privileged site. By contrast, a similar inoculation of tumor cells is rapidly rejected from nonprivileged ocular sites (subconjunctiva).
B R, Ksander, J W, Streilein
openaire   +2 more sources

Immunological Studies in Human Schistosomiasis

The American Journal of Tropical Medicine and Hygiene, 1977
Complement dependent cytotoxic antibodies for Schistosoma mansoni schistosomules were studied in a Brazilian population. The sera of S. mansoni-infected patients gave a high percentage of cytotoxicity (63.4%) compared with sera from persons not infected (8.7%). The IgG class and the specificity of these cytotoxic antibodies are defined.
Capron, Monique   +4 more
openaire   +2 more sources

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