Results 271 to 280 of about 34,355 (311)
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A Reappraisal of Cytotoxic Lymphocytes in Human Tumor Immunology

1987
Extensive work done at the Section of Clinical Tumor Virology and Immunology, Department of Medicine, The University of Texas M. D. Anderson Hospital, from 1968 to 1978 on the cytotoxicity of lymphocytes to cultured human tumor cells is reviewed. The early results and concepts are now reinterpreted in the light of newer knowledge generated worldwide in
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Failure of infiltrating precursor cytotoxic T cells to acquire direct cytotoxic function in immunologically privileged sites.

The Journal of Immunology, 1990
Abstract Minor H incompatible P815 tumor cells inoculated into the anterior chamber (AC) of the eyes of BALB/c mice grow progressively, revealing this to be an immunologically privileged site. By contrast, a similar inoculation of tumor cells is rapidly rejected from nonprivileged ocular sites (subconjunctiva). Mice with progressively
B R, Ksander, J W, Streilein
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Immunologically Mediated Cytotoxicity against Human Eye Muscle Cells in Graves’ Ophthalmopathy*

The Journal of Clinical Endocrinology & Metabolism, 1986
The possible roles of antibody-mediated complement-dependent cytotoxicity (AMC), antibody-dependent killer (K) cell-mediated cytotoxicity (ADCC), and spontaneous, natural killer (NK) cell-mediated cytotoxicity (NKC) against human eye muscle cells in the pathogenesis of Graves' ophthalmopathy were investigated, using as targets human eye muscle cells ...
P W, Wang   +5 more
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Antibody-Mediated Complement-Dependent Cytotoxicity in Immunologically Induced Experimental Colon Disease

International Archives of Allergy and Applied Immunology, 2009
Rabbits immunized with a saline extract of intestinal tissue in complete Freund’s adjuvant produce antibody which mediates complement-dependent cytotoxicity for colon epithelial cells in vitro. The presence of this antibody did not correlate with histologic alterations of the colon in the immunized rabbits.
B S, Rabin, E, Herrington
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The Role of the immunological Synapse Formed by Cytotoxic Lymphocytes in Immunodeficiency and Anti-Tumor immunity

Critical Reviews in Immunology, 2015
A synapse is a specialized structure that forms when the plasma membrane of two cells come into close contact to facilitate communication and signaling. Cells of the immune system form 'immunological' synapses that have an ordered structure and are essential for immune cell activation, function and homeostasis.
Conor J, Kearney   +3 more
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The Influence of Ultraviolet Light on Immunological Cytotoxicity in the Skin

Photochemistry and Photobiology, 1997
D A, Norris   +3 more
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An immunological suppressor cell inactivating cytotoxic T-lymphocyte precursor cells recognizing it

Nature, 1980
The immune system does not normally react against self components. Originally, it was postulated that self-reactive cells were somehow deleted or blocked. More recent thinking is that such cells are suppressed by regulatory networks similar to those limiting the immune response against non-self determinants. Both mechanisms may exist. I describe here a
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[Study on cytotoxicity to leukemia cell and enhancement of immunologic functions of jiexinkang].

Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University, 2002
Cytotoxicity to leukemia cell and enhancement of immunologic functions of jiexinkang (JXK, traditional Chinese medicine) were observed in 34 cases of leukemia in vitro. The results showed that the leukemia cytotoxicity in the group of vincristine combined with JXK was significantly higher than that in vincristine alone.
Z, Xie   +5 more
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A longitudinal study of immunological parameters in multiple sclerosis. Cytotoxic antibodies.

Journal of the neurological sciences, 1979
Complement-dependent gliotoxic antibody activity was determined in 22 patients with multiple sclerosis (MS) and 19 normal control persons. Peripheral blood serum was collected from MS patients at about 4-week intervals for one year, and the results of cytotoxicity tests correlated with the course of disease.
P, Mar, T, Gradl, C, Dörner
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[The lymphocyte cytotoxicity test in tumor immunology (author's transl)].

Klinische Wochenschrift, 1975
The cytotoxic action of lymphocytes on cancer cells in vitro indicates sensitization of the patient against his own tumor. The technical difficulities of this test and possibilities of standardization and simplifying the procedure are discussed. Critical steps are isolation of lymphocytes and culturing target cells without loosing their specific ...
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