Results 261 to 270 of about 54,012 (308)
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Importance of Immunologically Competent Cells in Contact-induced Cytotoxicity
Nature, 1970IT is not yet clear whether the cytotoxicity observed when target cells and allogeneic lymphoid cells are cultured together in vitro1,2 is mediated by an immunological mechanism. Cell death has been attributed to contact with the antigenically or structurally incompatible lymphocyte cell surface rather than by any conventional immunological reaction2,3.
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Immunologically Mediated Cytotoxicity against Human Eye Muscle Cells in Graves’ Ophthalmopathy*
The Journal of Clinical Endocrinology & Metabolism, 1986The possible roles of antibody-mediated complement-dependent cytotoxicity (AMC), antibody-dependent killer (K) cell-mediated cytotoxicity (ADCC), and spontaneous, natural killer (NK) cell-mediated cytotoxicity (NKC) against human eye muscle cells in the pathogenesis of Graves' ophthalmopathy were investigated, using as targets human eye muscle cells ...
P W, Wang +5 more
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International Archives of Allergy and Immunology, 1980
Rabbits immunized with a saline extract of intestinal tissue in complete Freund’s adjuvant produce antibody which mediates complement-dependent cytotoxicity for colon epithelial cells <i>in vitro</i>. The presence of this antibody did not correlate with histologic alterations of the colon in the immunized rabbits.
B S, Rabin, E, Herrington
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Rabbits immunized with a saline extract of intestinal tissue in complete Freund’s adjuvant produce antibody which mediates complement-dependent cytotoxicity for colon epithelial cells <i>in vitro</i>. The presence of this antibody did not correlate with histologic alterations of the colon in the immunized rabbits.
B S, Rabin, E, Herrington
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[Endometriosis and discouragement of immunology cytotoxic characteristics].
Ginecologia y obstetricia de Mexico, 2004To determine the immunology kind of response Th1 (cytotoxic) or Th2 (humoral) prevailing at peripheral and peritoneal environment at endometriosis women (ENW).Observational, transverse, analytical, retrospective, cases and controls.Cooperative and cytotoxic lymphocytes obtained from peritoneal fluid (PF) and peripheral blood (PB) were used to determine
César Angel, Hernández Guerrero +5 more
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HIV-specific cytotoxic T-lymphocyte activity in immunologically normal HIV-infected persons
AIDS, 1998CD8+ T-cell counts usually increase soon after infection with HIV, whereas CD4+ cell counts decrease. The result of these changes in T-cell subpopulation subsets in most HIV-infected subjects is inversion of the CD4 : CD8 ratio from greater than 1.0 typical of uninfected persons to less than 1.0 after infection.Six HIV-infected individuals were ...
N F, Bernard +5 more
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Cytotoxicity and Immunological Response of Gold and Silver Nanoparticles of Different Sizes
Small, 2009AbstractThe immunological response of macrophages to physically produced pure Au and Ag nanoparticles (NPs) (in three different sizes) is investigated in vitro. The treatment of either type of NP at ≥10 ppm dramatically decreases the population and increases the size of the macrophages.
Hung-Jen, Yen +2 more
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The Journal of Immunology, 1990
Abstract Minor H incompatible P815 tumor cells inoculated into the anterior chamber (AC) of the eyes of BALB/c mice grow progressively, revealing this to be an immunologically privileged site. By contrast, a similar inoculation of tumor cells is rapidly rejected from nonprivileged ocular sites (subconjunctiva).
B R, Ksander, J W, Streilein
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Abstract Minor H incompatible P815 tumor cells inoculated into the anterior chamber (AC) of the eyes of BALB/c mice grow progressively, revealing this to be an immunologically privileged site. By contrast, a similar inoculation of tumor cells is rapidly rejected from nonprivileged ocular sites (subconjunctiva).
B R, Ksander, J W, Streilein
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Immunological Studies in Human Schistosomiasis
The American Journal of Tropical Medicine and Hygiene, 1977Complement dependent cytotoxic antibodies for Schistosoma mansoni schistosomules were studied in a Brazilian population. The sera of S. mansoni-infected patients gave a high percentage of cytotoxicity (63.4%) compared with sera from persons not infected (8.7%). The IgG class and the specificity of these cytotoxic antibodies are defined.
Capron, Monique +4 more
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A Reappraisal of Cytotoxic Lymphocytes in Human Tumor Immunology
1987Extensive work done at the Section of Clinical Tumor Virology and Immunology, Department of Medicine, The University of Texas M. D. Anderson Hospital, from 1968 to 1978 on the cytotoxicity of lymphocytes to cultured human tumor cells is reviewed. The early results and concepts are now reinterpreted in the light of newer knowledge generated worldwide in
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An immunological suppressor cell inactivating cytotoxic T-lymphocyte precursor cells recognizing it
Nature, 1980The immune system does not normally react against self components. Originally, it was postulated that self-reactive cells were somehow deleted or blocked. More recent thinking is that such cells are suppressed by regulatory networks similar to those limiting the immune response against non-self determinants. Both mechanisms may exist. I describe here a
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