Results 111 to 120 of about 686,731 (316)
Molecules, 2015 Mosses have been neglected as a study subject for a long time. Recent research shows that mosses contain remarkable and unique substances with high biological activity.
Laura Klavina +6 more
doaj +1 more source
CD56 in the Immune System: More Than a Marker for Cytotoxicity?
Frontiers in Immunology, 2017 Over the past years, the phenotypic and functional boundaries distinguishing the main cell subsets of the immune system have become increasingly blurred. In this respect, CD56 (also known as neural cell adhesion molecule) is a very good example.
H. Van Acker +3 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam +9 more
wiley +1 more source
Assessment of the cytotoxicity of chlorhexidine by employing an in vitro mammalian test system
Journal of Dental Sciences, 2014 Background/purpose: Chlorhexidine (CHX), a chlorophenyl biguanide with broad antibacterial action, has been widely used in dentistry. The initial uses of CHX in dentistry were to wash operation site and to disinfect root canals. Recently, the addition of
Yi-Ching Li +4 more
doaj +1 more source
Bayesian Networks Aplied to Therapy Monitoring [PDF]
arXiv, 2013 We propose a general Bayesian network model for application in a wide class of problems of therapy monitoring. We discuss the use of stochastic simulation as a computational approach to inference on the proposed class of models. As an illustration we present an application to the monitoring of cytotoxic chemotherapy in breast cancer.
arxiv
Particle and Fibre Toxicology, 2014 Silver nanoparticles (AgNPs) are currently one of the most manufactured nanomaterials. A wide range of toxicity studies have been performed on various AgNPs, but these studies report a high variation in toxicity and often lack proper particle ...
A. Gliga +4 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan +10 more
wiley +1 more source
Cell Division, Cytotoxicity, and the Assays Used in the Detection of Cytotoxicity
, 2019 Cell division is a phenomenon that is encountered in all cells in nature. While normal cell division results in proliferation in single-celled organisms, and development and repair in multicellular organisms, aberrant and untimely cell division results in tumor formation.
İstifli, Erman Salih +2 more
openaire +5 more sources
Cytotoxic Activities and Structure-Cytotoxic Relationships of Steroidal Saponins.
Biological and Pharmaceutical Bulletin, 2001 We have systematically examined the cytotoxic activities of the steroidal saponins mainly isolated from the Liliaceae plants against HL-60 human promyelocytic leukemia cells and found several structure-activity relationships. Some steroidal saponins evaluated in the assay system showed considerable cytotoxic activities, which were almost as potent as ...
Yoshihiro Mimaki +3 more
openaire +4 more sources
Molecules, 2014 Elaeagnus oldhamii Maxim. is a commonly used traditional herbal medicine. In Taiwan the leaves of E. oldhamii Maxim. are mainly used for treating lung disorders. Twenty five compounds were isolated from the leaves of E. oldhamii Maxim.
Chi-Ren Liao +6 more
doaj +1 more source