Results 41 to 50 of about 686,731 (316)

Attaining scalable storage-expansion dualism for bioartificial tissues [PDF]

open access: yesarXiv, 2021
The untenable dependence of cryopreservation on cytotoxic cryoprotectants has motivated the mining of biochemical libraries to identify molecular features marking cryoprotectants that may prevent ice crystal growth. It is hypothesized that such molecules may be useful across all temperatures eliminating cellular destruction due to equilibration ...
arxiv  

Cytotoxicity‐dependent APO‐1 (Fas/CD95)‐associated proteins form a death‐inducing signaling complex (DISC) with the receptor.

open access: yesEMBO Journal, 1995
APO‐1 (Fas/CD95), a member of the tumor necrosis factor receptor superfamily, induces apoptosis upon receptor oligomerization. In a search to identify intracellular signaling molecules coupling to oligomerized APO‐1, several cytotoxicity‐dependent APO‐1 ...
F. Kischkel   +6 more
semanticscholar   +1 more source

Antibiotic and cytotoxic peptides [PDF]

open access: yesBeilstein Journal of Organic Chemistry, 2012
Through evolution, nature has provided practically all organisms with secondary metabolites: chemical compounds that provide the producing species with specific protective mechanisms or other advantages. Among these, there are, e.g., peptides that display antibiotic/antimicrobial activity.
openaire   +5 more sources

Antioxidative Effect of Aster yomena (Kitm.) Extract on C6 Glioma Cell Line Damaged by AlCl3, Dementia Inducer

open access: yesKorean Journal of Clinical Laboratory Science, 2020
This study examined the neuronal cytotoxicity of aluminum chloride (AlCl3), a dementia inducer, and the protective effects of Aster yomena (Kitam.)(AY) extract on AlCl3-induced cytotoxicity in cultured C6 glioma cells.
Young-Mi Seo
doaj   +1 more source

The Natural Cytotoxicity Receptors in Health and Disease

open access: yesFrontiers in Immunology, 2019
The Natural Cytotoxicity Receptors (NCRs), NKp46, NKp44, and NKp30, were some of the first human activating Natural Killer (NK) cell receptors involved in the non-MHC-restricted recognition of tumor cells to be cloned over 20 years ago.
A. Barrow, C. Martin, M. Colonna
semanticscholar   +1 more source

Primary extranodal diffuse large B‐cell lymphoma: Molecular features, treatment, and prognosis

open access: yesAging and Cancer, Volume 3, Issue 3-4, Page 133-146, September-December 2022., 2022
One‐third of DLBCL arises from extranodal organs and is challenging to manage. Molecular features are critical to elucidate the differences in clinical features, predict the disease prognosis, and improve effective targeted therapeutic strategies. Abstract Diffuse large B‐cell lymphoma (DLBCL) is the most common subtype of non‐Hodgkin's lymphoma and ...
Si‐Yuan Chen   +3 more
wiley   +1 more source

Cytotoxicity - Definition, Identification, and Cytotoxic Compounds

open access: yes, 2019
Life is a short process between mortality and immortality. In fact, immortality is not as interesting as imagined. Together with the transition from unicellular cells to multicellular organisms, cytotoxicity has a different meaning. While cytotoxicity in a single-celled organism refers to death, it acts as one of the driving forces of differentiation ...
İstifli, Erman Salih, İla, Hasan Basri
openaire   +3 more sources

Synthesis and Cytotoxicity of Y2O3 Nanoparticles of Various Morphologies

open access: yesNanoscale Research Letters, 2009
As the field of nanotechnology continues to grow, evaluating the cytotoxicity of nanoparticles is important in furthering their application within biomedicine.
Gordonov Simon   +4 more
doaj   +1 more source

Towards effective immunotherapy of myeloma: enhanced elimination of myeloma cells by combination of lenalidomide with the human CD38 monoclonal antibody daratumumab

open access: yesHaematologica, 2011
Background In our efforts to develop novel effective treatment regimens for multiple myeloma we evaluated the potential benefits of combining the immunomodulatory drug lenalidomide with daratumumab.
Michael. S. van der Veer   +7 more
doaj   +1 more source

NK cells switch from granzyme B to death receptor–mediated cytotoxicity during serial killing

open access: yesJournal of Experimental Medicine, 2019
Natural killer cells can kill infected and transformed cells via two different cell death mechanisms. Prager et al. show that NK cells quickly kill their first targets by releasing cytotoxic granules and only use the slower death receptor–mediated ...
I. Prager   +11 more
semanticscholar   +1 more source

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