Update: Enzymatische Synthese für industrielle Anwendungen
Angewandte Chemie, Volume 137, Issue 27, July 1, 2025.Die Biokatalyse hat sich zu einer nachhaltigen und wettbewerbsfähigen Alternative zur herkömmlichen chemischen Synthese entwickelt und ermöglicht die enzymbasierte Herstellung nicht nur von chemischen Grundstoffen, sondern auch von (nicht natürlichen) Aminosäuren, (seltenen) Zuckern und synthetischen Nukleotiden.
Thomas Bayer +4 more
wiley +1 more source
EFSA Journal, Volume 17, Issue 7, July 2019., 2019 Abstract The qualified presumption of safety (QPS) procedure was developed to provide a harmonised generic pre‐evaluation to support safety risk assessments of biological agents performed by EFSA's Scientific Panels. The taxonomic identity, body of knowledge, safety concerns and antimicrobial resistance were assessed.
EFSA Panel on Biological Hazards (BIOHAZ) +26 more
wiley +1 more source
Construction and Optimization of Biosynthetic Pathway for the Production of D-Allulose from Glucose in Escherichia coli [PDF]
A pathway in Escherichia coli BL21 (DE3) was constructed to produce D-allulose from D-glucose via a phosphorylation-dephosphorylation strategy. The genes related to competitive pathways were deleted using the CRISPR/Cas9 system, and allulose-6-phosphate
JIANG Yawen, ZHANG Cangping, YANG Shaoqing, JIANG Zhengqiang, LI Yanxiao, YAN Qiaojuan
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Learning from Protein Engineering by Deconvolution of Multi‐Mutational Variants
Angewandte Chemie International Edition, Volume 63, Issue 36, September 2, 2024.First derivative of a typical experimental enzyme fitness pathway landscape mapped on the basis of ΔG values, in this case of 24 trajectories in the deconvolution of a 4‐mutational variant. Green areas indicate negative slopes and define trajectories involved in energetically favored stages, while red areas indicate positive slopes representing ...
Frank Hollmann +2 more
wiley +1 more source
Biocatalysis in packed-bed reactors: immobilization as an enabling technology [PDF]
Biocatalysis and flow chemistry are two complementary technologies that can be used to produce chemicals in a more efficient, sustainable, and safe manner. Enzyme immobilization is key to enabling their combination.
Fernández Regueiro, Cristina Lía +2 more
core +3 more sources
Thermostable D-Allulose 3-Epimerase for Long-Term Food-Compatible Continuous Production Systems
Applied SciencesD-allulose is a rare sugar with promising applications in food and health industries, owing to its low caloric value and multiple health benefits.
Jiawei Cui, Yan Li, Ming Yan
doaj +1 more source
Preparation of Catalyst ZIF-67 and Optimize on the Synthesis of D-Allulose [PDF]
To reduce the manufacturing cost of D-allulose, a recyclable and reusable inorganic catalyst was developed for D-allulose production, and process using this catalyst to produce D-allulose also was optimized in this article. Zeolitic imidazolate framework-
Changhe DING +6 more
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Adaptive Steered Molecular Dynamics Combined With Protein Structure Networks Revealing the Mechanism of Y68I/G109P Mutations That Enhance the Catalytic Activity of D-psicose 3-Epimerase From Clostridium Bolteae [PDF]
, 2018 The scarcity, richness, and other important physiological functions of D-psicose make it crucial to increase the yield of D-psicose. The production of D-psicose can be accomplished by D-psicose 3-epimerase (DPEase) from Clostridium bolteae (CbDPEase ...
Jingxuan Zhu +6 more
core +2 more sources
Study on preparation technology of alorulose enzyme fixed resin material [PDF]
This study focused on the biosynthesis of D-allulose enzyme, the enzyme immobilization technology and its application in industrial production.
Qin, Sihan
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