Results 71 to 80 of about 1,423 (137)
Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 2, April 2025.ABSTRACT Background G protein–coupled receptor 40 (GPR40) acts as a modulator of various physiological functions, including glycaemic lowering, anti‐inflammation and antioxidative stress, in several tissues. However, the role of GPR40 in skeletal muscles remains unclear.
Joo Won Kim +9 more
wiley +1 more source
European Journal of Organic Chemistry, Volume 28, Issue 11, March 17, 2025.A refresh of the well‐known myo‐inositol chemistry is reported with a special focus on 2‐O‐alkylated compounds, chiro‐1‐inosose, 1,2‐diketone and 3‐deoxy‐1,2‐diketone derivatives optimizing the synthetic protocol also in gram scale. Orthogonally protected chiro‐1‐inosose was transformed into cyanohydrins to access to poly‐hydroxylated‐(aminomethyl ...
Francesco Anastasi +7 more
wiley +1 more source
Pakistan Journal of Medicine and DentistryBackground: Polycystic ovarian syndrome (PCOS) is an endocrinological disease of women of the reproductive age group. The study aimed to compare the efficacy of Myo-inositol and folic acid with and without D-chiro-inositol in the improvement of symptoms
Reja Akram +4 more
doaj +1 more source
New prospects of the integrative therapy for polycystic ovary syndrome in women with the disorders of carbohydrate and lipid metabolism: a comparative study. [PDF]
РМЖ. Мать и дитя, 2020 Yu.E. Dobrokhotova, I.A. Lapina, T.G. Chirvon, V.V. Taranov Pirogov Russian National Research Medical University, Moscow, Russian Federation Background: long-term combined estrogen-progestin oral contraceptive pills (COCPs)
Yu.E. Dobrokhotova +3 more
doaj
The role of inositol in improving fertility in patients with PCOS
Journal of Education, Health and SportIntroduction and purpose Polycystic ovary syndrome is a common reproductive disorder, accompanied primarily by hyperandrogenism and insulin resistance. Myo-inositol (MI) and D-chiro-inositol (DCI), have emerged as potential therapeutic agents due to
Kamila Turek +9 more
doaj +1 more source
Inositols in Insulin Signaling and Glucose Metabolism
International Journal of Endocrinology, 2018 In the past decades, both the importance of inositol for human health and the complex interaction between glucose and inositol have been the subject of increasing consideration. Glucose has been shown to interfere with cellular transmembrane transport of
Arturo Bevilacqua, Mariano Bizzarri
doaj +1 more source
Myo-Inositol and D-Chiro-Inositol as Modulators of Ovary Steroidogenesis: A Narrative Review. [PDF]
Nutrients, 2023 Bizzarri M +4 more
europepmc +1 more source
Gynecological EndocrinologyIn this article, we present a narrative review on the use of inositol in the treatment of polycystic ovary syndrome (PCOS). Of the different inositols that exist, only myo-inositol (MYO) and D-chiro inositol (DCI) have been studied in the treatment of ...
Iñaki Lete +4 more
doaj +1 more source
D-Chiro-Inositol and Myo-Inositol Induce WAT/BAT Trans-Differentiation in Two Different Human Adipocyte Models (SGBS and LiSa-2). [PDF]
Int J Mol Sci, 2023 Monastra G +5 more
europepmc +1 more source
The Improvement Effect of D-Chiro-Inositol and Ecklonia cava K. in the Rat Model of Polycystic Ovarian Syndrome. [PDF]
Front Pharmacol, 2022 Yang H +7 more
europepmc +1 more source