Results 101 to 110 of about 14,563,409 (378)

Dose response relationship between D-dimer level and mortality in critically ill COVID-19 patients: a retrospective observational study [version 2; peer review: 1 approved, 2 approved with reservations]

open access: yesF1000Research, 2023
Background: Coronavirus disease 2019 (COVID-19) is a global pandemic. Coagulopathy is one of the most common complications characterized by increased D-dimer level. We aimed to investigate the dose-response relationship between elevated D-dimer level and
Ponco Birowo   +7 more
doaj   +1 more source

Can we use biomarkers of coagulation to predict which patients with foot and ankle injury will develop vein thrombosis? [PDF]

open access: yes, 2019
Background Our aim was to determine whether plasma levels of Tissue Factor (TF), Vascular Cell Adhesion Molecule 1 (VCAM-1), Interleukin 6 (IL-6) or D-dimer after foot and ankle injury could predict which patients would develop deep vein thrombosis ...
Andrew Cleves   +5 more
core   +2 more sources

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

open access: yesFEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Evaluation of treatment for diffuse large B-cell lymphoma using plasma D-dimer levels

open access: yesScientific Reports
It has been documented that D-dimer levels have potential utility as a measure of tumor activity in diffuse large B-cell lymphoma (DLBCL), however whether it can be used as a predictive marker of treatment outcome has not been established.
Ruonan Shao   +8 more
doaj   +1 more source

Systematic assessment of venous thromboembolism in COVID-19 patients receiving thromboprophylaxis: incidence and role of D-dimer as predictive factors

open access: yesJournal of Thrombosis and Thrombolysis, 2020
Coagulopathy in COVID-19 is a burning issue and strategies to prevent thromboembolic events are debated and highly heterogeneous. The objective was to determine incidence and risk factors of venous thromboembolism (VTE) in COVID-19 inpatients receiving ...
M. Artifoni   +7 more
semanticscholar   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Super Formula for Soluble C-Type Lectin-Like Receptor 2 × D-Dimer in Patients With Acute Cerebral Infarction

open access: yesClinical and Applied Thrombosis/Hemostasis
Acute cerebral infarction (ACI) includes atherosclerotic and cardiogenic ACI and involves a thrombotic state, requiring antithrombotic treatment. However, the thrombotic state in ACI cannot be evaluated using routine hemostatic examinations.
Toshitaka Kamon MD   +12 more
doaj   +1 more source

Prevalence of pulmonary embolism in patients with COVID-19 pneumonia and high D-dimer values: A prospective study

open access: yesPLoS ONE, 2020
Introduction Coronavirus disease 2019 (COVID-19) pneumonia is associated to systemic hyper-inflammation and abnormal coagulation profile. D-dimer elevation is particularly frequent, and values higher than 1μg/mL have been associated with disease severity
A. Alonso-Fernández   +16 more
semanticscholar   +1 more source

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