D-penicillamine induced degenerative dermopathy
Indian Journal of Dermatology, 2015 D-penicillamine interferes with elastin and collagen metabolism and produces several cutaneous and multi-systemic side-effects. We present two cases of Wilson′s disease who on long-term penicillamine therapy developed drug-induced degenerative dermopathy
Sujay Khandpur +4 more
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Management of children and adolescents with Wilson Disease and neurological worsening following D–Penicillamine therapy: A single centre experience [PDF]
Annals of Indian Academy of Neurology, 2022 Background: Most centers in developing countries prefer chelation therapy with D-penicillamine for the management of Wilson's disease (WD) because of its easy availability and affordability. Neurological worsening following treatment with D-penicillamine
Madhan Kumar +5 more
doaj +2 more sources
D-Penicillamine: The State of the Art in Humans and in Dogs from a Pharmacological and Regulatory Perspective [PDF]
Antibiotics, 2021 Chelant agents are the mainstay of treatment in copper-associated hepatitis in humans, where D-penicillamine is the chelant agent of first choice. In veterinary medicine, the use of D-penicillamine has increased with the recent recognition of copper ...
Michela Pugliese +6 more
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Comparison of the Effectiveness and Safety of d-Penicillamine and Zinc Salt Treatment for Symptomatic Wilson Disease: A Systematic Review and Meta‐Analysis [PDF]
Frontiers in Pharmacology, 2022 Background: Pharmacological therapy is currently the main treatment method for patients with Wilson disease (WD). We aimed to evaluate the efficacy and safety of the common treatment regimens in these patients.Methods: We conducted a systemic review and ...
Shan Tang +10 more
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D-penicillamine Induced Myasthenia Gravis in Wilson’s Disease: A Case Report [PDF]
Journal of Nepal Medical Association, 2022 Myasthenia gravis is a neuromuscular junction disorder characterised by fluctuating muscle weakness, improved by using anti-cholinesterase drugs. In addition to the autoimmune aetiology, various factors such as infections, surgery, and drugs are known ...
Lekhjung Thapa +7 more
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Outcomes of Tiopronin and D-Penicillamine Therapy in Pediatric Cystinuria: A Clinical Comparison of Two Cases [PDF]
ReportsBackground and Clinical Significance: Cystinuria is the most common genetic cause of pediatric nephrolithiasis, characterized by impaired renal cystine reabsorption and resulting in increased urinary cystine excretion.
Brooke Schaefer +2 more
doaj +2 more sources
D-Penicillamine-Induced Myasthenia Gravis—A Probable Complication of Wilson’s Disease Treatment—A Case Report and Systematic Review of the Literature [PDF]
Life, 2023 Wilson’s disease (WD) is a genetic disorder with copper accumulation in various tissues leading to related clinical symptoms (mainly hepatic and neuropsychiatric) which can be in 85% of patients successfully treated with anti-copper agents.
Agnieszka Antos +4 more
doaj +2 more sources
Safety of penicillamine and trientine in the treatment of Wilson's disease: An analysis of the FDA Adverse Event Reporting System (FAERS) database. [PDF]
PLoS ONEBackgroundPenicillamine(D-Penicillamine) and trientine are first-line therapies for Wilson's Disease (WD), yet real-world data on their adverse events (AEs) remain scarce.
Wenlong Qian +12 more
doaj +2 more sources
Benefits and drawbacks of current copper chelators in Wilson disease [PDF]
Romanian Journal of Neurology, 2023 Background. Wilson disease (WD) is an autosomal-recessive disorder of copper metabolism, caused by mutations in the ATP7B gene, which codes for a membrane-bound copper-binding ATPase.
Ioan-Cristian Lupescu +6 more
doaj +1 more source
D-penicillamine-induced Elastosis Perforans Serpiginosa [PDF]
Chinese Medical Journal, 2017 Xue-Yan Yao +6 more
doaj +2 more sources