Results 31 to 40 of about 15,206,096 (240)

D-Penicillamine modulates hydrogen sulfide (H2S) pathway through selective inhibition of cystathionine-γ-lyase. [PDF]

Br J Pharmacol, 2016
Brancaleone V, Esposito I, Gargiulo A, Vellecco V, Asimakopoulou A, Citi V, Calderone V, Gobbetti T, Perretti M, Papapetropoulos A, Bucci M, Cirino G.   +11 more
europepmc   +2 more sources

Synthesis and Characterization of Gold Chiral Nanoparticles Functionalized by a Chiral Drug

Nanomaterials, 2023
Inorganic chiral nanoparticles are attracting more and more attention due to their peculiar optical properties and potential biological applications, such as bioimaging, therapeutics, and diagnostics.
Simona Bettini, Michela Ottolini, Donato Valli, Rosanna Pagano, Chiara Ingrosso, Maarten Roeffaers, Johan Hofkens, Ludovico Valli, Gabriele Giancane   +8 more
doaj   +1 more source

Oxidative stress and neurobehavioural changes in rats following copper exposure and their response to MiADMSA and d-penicillamine

Toxicology Research and Application, 2019
An increase in copper concentration in body may lead to hepatolenticular degeneration which is considered as one clinical feature of Wilson’s disease.
S. Quamar, Jayant Kumar, Awanish Mishra, S. Flora   +3 more
semanticscholar   +1 more source

Eosinophilia in D-penicillamine therapy. [PDF]

Annals of the Rheumatic Diseases, 1983
Cross-sectional and longitudinal studies have been carried out to determine the incidence and clinical significance of eosinophilia in patients taking penicillamine for rheumatoid arthritis. In a cross-sectional study of 204 patients eosinophilia was found with equal frequency during treatment with penicillamine, gold, and nonsteroidal anti ...
D L Scott, G C Zaphiropoulos, D H Smith
openaire   +3 more sources

Nephrotic syndrome after treatment with D-penicillamine in a patient with Wilson’s disease

Romanian Journal of Laboratory Medicine, 2014
Wilson’s disease is an inherited autosomal recessive disorder of copper balance leading to accumulation of copper mainly in liver and brain result from absent or reduced function of copper-transporting P-type ATPase.
Kostadinova Anna D., Mihaylov Marian Y., Ivanova Irena D., Robeva Rayna T.   +3 more
doaj   +1 more source

An Outline of D-penicillamine Metabolism [PDF]

Proceedings of the Royal Society of Medicine, 1977
In a study using 14C-D-penicillamine in a normal subject only 50% of the D-penicillamine was absorbed from the gut. The major urinary metabolites are cysteine-penicillamine and penicillamine disulphide. S-methyl-D-penicillamine is the only biochemically transformed metabolite so far identified.
openaire   +3 more sources

Metabolic balances of sulfur in patients with hepatolenticular degeneration and effect of the use of D-penicillamine

Arquivos de Neuro-Psiquiatria, 1969
The metabolic balances of sulfur in two cases of hepatolenticular degeneration were studied. A positive balance was found in both cases; in one patient submitted to mixed diet, the average was significantly higher than the normal mean. The administration
Horacio M. Canelas, Francisco B. De Jorge, Waldir A. Tognola   +2 more
doaj   +1 more source

Protective Effects of D-Penicillamine on Catecholamine-Induced Myocardial Injury. [PDF]

Oxid Med Cell Longev, 2016
Iron and copper release participates in the myocardial injury under ischemic conditions and hence protection might be achieved by iron chelators. Data on copper chelation are, however, sparse.
Říha M, Hašková P, Martin J, Filipský T, Váňová K, Vávrová J, Holečková M, Homola P, Vítek L, Palicka V, Šimůnek T, Mladěnka P.   +11 more
europepmc   +2 more sources

Origin of Long-Term Storage Stability and Nitric Oxide Release Behavior of CarboSil Polymer Doped with S-Nitroso-N-acetyl-d-penicillamine

ACS Applied Materials and Interfaces, 2015
The prolonged and localized delivery of nitric oxide (NO), a potent antithrombotic and antimicrobial agent, has many potential biomedical applications.
Yaqi Wo, Zi Li, E. Brisbois, A. Colletta, Jianfeng Wu, T. Major, C. Xi, R. Bartlett, A. Matzger, M. Meyerhoff   +9 more
semanticscholar   +1 more source

Validity of D-penicillamine in experimental cerebral vasospasm therapy

Interdisciplinary Neurosurgery
Background: Cerebral vasospasm is a reversible vessel constriction following subarachnoid hemorrhage. Immunoreactive and inflammatory mechanisms induce long-term vasoconstriction and vessel dilatation inhibition.
Ersin Haciyakupoglu, Evren Yüvrük, Sebahattin Haciyakupoglu, Milos Arsenovic, Erol Akgül, Dervis Mansuri Yilmaz, Sait Polat   +6 more
doaj   +1 more source