Results 41 to 50 of about 12,790 (151)

Cuprizone-induced Demyelination in Mouse Brain is not due to Depletion of Copper

ASN Neuro, 2022
The cuprizone (CPZ) model allows the study of the biochemical processes underlying nonautoimmune-mediated demyelination, remyelination, and chronic white matter disease progression.
Megan L. Morgan, Wulin Teo, Yda Hernandez, Craig Brideau, Karen Cummins, Hedwich F. Kuipers, Peter K. Stys   +6 more
doaj   +1 more source

Recent Advances in Metal‐Organic Framework‐Integrated Nanocomposite Hydrogels for Sensors and Sensing Systems

SmartMat, Volume 7, Issue 1, February 2026.
Metal‐organic framework–hydrogel composites are explored as multifunctional materials for next‐generation sensors and sensing systems. This review summarizes recent advances in employing these smart composites to fabricate optical, electrochemical, and electromechanical sensors, emphasizing their potential in healthcare, biomedical diagnostics ...
Md Sazzadur Rahman, Emna Helal, Nicole R. Demarquette   +2 more
wiley   +1 more source

Correction to "Discussion on the Mechanism of Gandoufumu Decoction Attenuates Liver Damage of Wilson's Disease by Inhibiting Autophagy through the PI3K/Akt/mTOR Pathway Based on Network Pharmacology and Experimental Verification". [PDF]

Mediators Inflamm
Mediators of Inflammation, Volume 2026, Issue 1, 2026.
europepmc   +2 more sources

Computer‐Assisted Dynamic Contrast–Enhanced Magnetic Resonance Imaging Quantification Method for Assessment of Synovial Inflammation in Active Arthritis: Correlation With Synovial and Blood Biomarkers

ACR Open Rheumatology, Volume 8, Issue 1, January 2026.
Objective To investigate the correlation and association between dynamic contrast–enhanced magnetic resonance imaging (DCE‐MRI) quantification (DEMRIQ) parameters with local and systematic markers of inflammation in patients with various etiologies of acute knee arthritis.
M. Boesen, D. Shakoor, O. Kubassova, R. Riis, H. Bliddal, C. Ballegaard, J. A. Carrino, E. M. Bartels   +7 more
wiley   +1 more source

Ultrabroadband Chiral Emission from Cu Nanocluster Eggshell Membrane/CsPbBr3 QD Composites with a Cholesteric Superstructures

Advanced Functional Materials, Volume 36, Issue 4, 12 January 2026.
This study presents a novel wide‐bandwidth circularly polarized luminescence (CPL) system combining Cu nanoclusters, perovskite quantum dots, and cholesteric liquid crystals. The design achieves strong CPL emission across 480–750 nm (glum up to 1.31 at 514 nm and 1.46 at 620 nm). Using biomaterials and a simple structure, it offers a promising strategy
Tan‐De Liu, Chia‐Chien Kuo, Yu‐Chieh Chang, Ting‐Wei Gu, Chun‐Ta Wang, Yi‐Hsin Chien, Wei‐Chun Lin   +6 more
wiley   +1 more source

Hepatic Lenticular Degeneration With Renal Tumors: A Case Series

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT This article presents a series of cases involving hepatic lenticular degeneration (Wilson's disease) complicated by renal tumors. It details the clinical manifestations, diagnostic procedures, treatment strategies, pathological features and outcomes of these patients. We found that this type of patient has an early‐onset disease, complex tumor
Haibing Xiao, Mintian Fei, Haoqiang Shi, Xinfeng Ma, Qili Xu, Yu Gao, Cheng Yang, Yu Yin, Jun Zhou, Chaozhao Liang   +9 more
wiley   +1 more source

From Radiocopper to Cold Copper: Mechanistic Modeling and Simulation to Define Clinical Response Criteria and Biomarkers for VTX‐801 in Wilson Disease

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 1, January 2026.
ABSTRACT We developed a comprehensive, mechanistic model of human copper metabolism to support biomarker qualification for VTX‐801, an adeno‐associated vector‐based gene therapy which is being developed to restore the mutated ATP7B copper transporter gene in Wilson disease (WD). The model integrates physiological copper kinetics with pathophysiological
Andreas Lindauer, Bernard Benichou, Gloria González Aseguinolaza, Jean‐Philippe Combal   +3 more
wiley   +1 more source

Chelation Therapy for Rare Earth Element Toxicity: Current Evidence, Challenges and Future Directions

Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 1, January 2026.
ABSTRACT The accelerating integration of rare earth elements (REEs) in advanced technologies has generated rising concern over human exposure and the attendant toxicological risks. This review presents an up‐to‐date synthesis of current evidence on REE toxicity across multiple exposure pathways, including inhalation, ingestion and occupational contact,
Jose L. Domingo
wiley   +1 more source

Effect of D-penicillamine in prevention of post operative pelvic adhesion formation in rat

Journal of Research in Medical Sciences, 2006
INTRODUCTION: Adhesion formation after pelvic surgery is still a major cause of several morbidities such as infertility, pain, bowel obstruction and subsequent intra-operative complications.
Ata-Allah Ghahiri, Elahe Zarean, Mehdi Rasti, Shahriar Adibi   +3 more
doaj  

Non‐canonical nitric oxide signalling and DNA methylation: Inflammation induced epigenetic alterations and potential drug targets

British Journal of Pharmacology, Volume 183, Issue 1, Page 24-39, January 2026.
Abstract DNA methylation controls DNA accessibility to transcription factors and other regulatory proteins, thereby affecting gene expression and hence cellular identity and function. As epigenetic modifications control the transcriptome, epigenetic dysfunction is strongly associated with pathological conditions and ageing.
Christopher H. Switzer
wiley   +1 more source