Results 251 to 260 of about 2,524,488 (277)

Diagnostic significance of CyclinD1 and D2-40 expression for follicular neoplasm of the thyroid

Pathology - Research and Practice, 2022
To evaluate the expression and differential diagnostic significance of CyclinD1 and D2-40 in follicular neoplasm (FN) and other thyroid adenomatoid lesions.A total of 144 cases of thyroid adenomatoid lesions were enrolled. Immunohistochemistry for CyclinD1 and D2-40 was performed.We found two patterns of CyclinD1 expression: nuclear (N) and cytoplasmic
Jun, Liu, Li-Li, Tao, Guang-Yin, Yu, Gang, Chen, Zhe, Wang, Kai-Yong, Mei, Xiu-Li, Xu, Xiao-Xin, Shi, Tai-Li, Li, Wei-Hua, Yin   +9 more
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D2-40 Expression in Primary Scarring and Nonscarring Alopecia

The American Journal of Dermatopathology, 2010
The pathogenesis of scarring alopecia is believed to be related to damage to stem cells within, and outside the confines of, the follicular bulge region. Scattered reports indicate that D2-40, a monoclonal antibody that specifically detects a fixation-resistant epitope on podoplanin, highlights the basal cell layer of the outer root sheath. Given this,
Meera, Mahalingam, Mai P, Hoang
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D2-40 Antibody is a Specific Marker for B2 Thymomas

Applied Immunohistochemistry & Molecular Morphology, 2017
The correlation between the worse outcome of thymomas and expression of podoplanin (D2-40 antibody) in neoplastic cells has been proved in recent studies. We investigated the expression of podoplanin in thymic epithelial tumors of different histologic types and stages resected in our institution.
Malgorzata, Szolkowska, Renata, Langfort, Sebastian, Winiarski, Piotr, Rudzinski, Dorota, Giedronowicz, Ewa, Szczepulska-Wojcik, Piotr, Ronduda, Beata, Maksymiuk, Tadeusz, Orlowski   +8 more
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Cutaneous Keratocyst With D2-40 Immunoreactivity in Basal Cell Nevus Syndrome

The American Journal of Dermatopathology, 2021
Abstract: Although not a diagnostic criterion for basal cell nevus syndrome (BCNS, OMIM#109400), cutaneous cysts, particularly epidermoid cysts, are common in this condition. Cutaneous keratocysts, on the other hand, are extremely rare in general and have been identified in only 5 patients with BCNS.
Clare A, Goggins, Michele L, Zerah, Florencia, Anatelli, Scott A, Norton   +3 more
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Mucinous Carcinoma of the Skin: Evaluation of Lymphatic Invasion With D2-40

The American Journal of Dermatopathology, 2008
Primary cutaneous mucinous carcinoma is a rare adnexal sweat gland neoplasm that mainly affects elderly people. Differential diagnosis includes mammary and gastrointestinal metastatic mucinous carcinoma (MC) and secondary cutaneous involvement by underlying neoplasms.
Sabela, Paradela, Iria, Castiñeiras, Jesús, Cuevas, Manuel, Almagro, Jesús, del Pozo, Eduardo, Fonseca   +5 more
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Diagnostic utility of D2‐40 and podoplanin in effusion cell blocks

Diagnostic Cytopathology, 2007
AbstractThe distinction between malignant mesothelioma and adenocarcinoma is a diagnostic challenge in cytologic specimens of effusion fluids. As for today, no single antibody has demonstrated absolute sensitivity or specificity for Mesothelioma. D2‐40 and podoplanin have recently been recognized to stain mesothelial cells.
Ritu, Bhalla, Momin T, Siddiqui, Daniza, Mandich, Richard W, Cartun, Mary D, Fiel-Gan, Aziza, Nassar, Srinivas R, Mandavilli   +6 more
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Significance of D2-40 expression in the diagnosis of gastrointestinal stromal tumor

Medical Molecular Morphology, 2008
We incidentally found the expression of D2-40 in Cajal interstitial cells for the immunohistochemical valuation of lymphatic invasion by gastric and colonic cancer cells. Therefore, we suggested that D2-40 might become an available marker for gastrointestinal stromal tumors (GISTs).
Naoto, Kuroda, Nobuyuki, Tanida, Kazuhisa, Oonishi, Kaori, Inoue, Masahiko, Ohara, Keiko, Mizuno, Takahiro, Taguchi, Yoshihiro, Hayashi, Kazuhiro, Hanazaki, Gang-Hong, Lee   +9 more
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Immunohistochemical demonstration of D2‐40 in basal cell carcinomas of the skin

Journal of Cutaneous Pathology, 2008
Background:  Recently, immunoreactivity to D2‐40, a monoclonal antibody to lymphatic endothelium, was shown in a subgroup of epidermal basal cells and the majority of squamous cell carcinomas, but the immunoreactivity to this antibody has not been examined in basal cell carcinomas (BCCs) of the skin.Methods:  Expression of D2‐40 was analyzed together ...
Mitsuaki, Ishida, Ryoji, Kushima, Hidetoshi, Okabe   +2 more
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Expression of D2‐40 in adjunct diagnosis of papillary thyroid carcinoma

APMIS, 2007
The clinical pathologic criteria for nuclear features of papillary thyroid carcinoma are subjective and sometimes cannot distinguish carcinoma from adenomatous goiter and follicular neoplasms. No single antibody has demonstrated high sensitivity or specificity in making these distinctions.
Sheng-Lan, Wang, Shau-Hsuan, Li, Wan-Tzu, Chen, Chee-Yin, Chai   +3 more
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Expression of the lymphatic marker podoplanin (D2-40) in human fetal eyes

Experimental Eye Research, 2014
During human ocular development, expression of proteins varies in different maturation stages. This study aims to characterize structures in human fetal eyes stained by the lymphatic marker podoplanin (D2-40) with emphasis on the stage of maturation and the presence of intraocular lymphatic structures.
Martina C, Herwig, Kathrin, Münstermann, Ute, Klarmann-Schulz, Simona L, Schlereth, Ludwig M, Heindl, Karin U, Loeffler, Annette M, Müller   +6 more
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