Results 71 to 80 of about 3,595 (167)

Dalbavancin utilization registry investigating value and effectiveness (DRIVE): Outcomes report on real-world use

Clinical Infection in Practice
Objectives: Dalbavancin has potent activity against Gram-positive pathogens, including methicillin-resistant Staphylococcus aureus, and is approved for treatment of acute bacterial skin and skin structure infections (ABSSSI).
Bruce M. Jones, Kerry O. Cleveland, Pedro L. Gonzalez, Urania Rappo, Todd Riccobene, Rosie D. Lyles   +5 more
doaj   +1 more source

Financial Analysis of Dalbavancin for Acute Bacterial Skin and Skin Structure Infections for Self-Pay Patients

Infectious Diseases and Therapy, 2020
Introduction Acute bacterial skin and skin structure infections (ABSSSI) are an increasing cause of admission in the self-pay population. We previously reported that patients with ABSSSI discharged to receive dalbavancin showed a decreased length of stay
Adam G. Pizzuti, E. Yancy Murray, Jamie L. Wagner, Derek A. Gaul, Christopher M. Bland, Bruce M. Jones   +5 more
doaj   +1 more source

A review of antibiotic safety in pregnancy—2025 update

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 45, Issue 4, Page 227-237, April 2025.
Abstract Antibiotics constitute the majority of prescriptions for women during pregnancy. Common bacterial infections, including urinary tract infections, skin and soft tissue infections, and upper and lower respiratory tract infections, are expected in pregnancy, similar to the general public.
Johny Nguyen, Victoria Madonia, Christopher M. Bland, Kayla R. Stover, Lea S. Eiland, Julia Keating, Madeline Lemmon, P. Brandon Bookstaver, as part of the Southeastern Research Group Endeavor (SERGE‐45) research network   +8 more
wiley   +1 more source

Complicated and deep bacterial skin and soft tissue infections

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 3, Page 357-375, March 2025.
Summary Complicated erysipelas, cellulitis, and necrotizing soft tissue infections belong to the spectrum of bacterial infections affecting the skin and underlying soft tissues. Their frequency as well as risk of recurrence and complicated disease course pose a significant health burden.
Christine Prodinger, Arno Lechner, Arno Hintersteininger, Jan Marco Kern, Matthias Meißnitzer, Damian Meyersburg, Johann W. Bauer, Martin Laimer   +7 more
wiley   +1 more source

Komplizierte und tiefe bakterielle Haut‐ und Weichteilinfektionen

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 3, Page 357-376, March 2025.
Zusammenfassung Komplizierte Erysipele, Phlegmone und nekrotisierende Weichteilinfektionen sind bakterielle Haut‐ und Weichteilinfektionen (BHWI), die aufgrund ihrer Häufigkeit, der Neigung zu Rezidiven und dem Auftreten komplizierter Verläufe ein bedeutendes Gesundheitsproblem darstellen.
Christine Prodinger, Arno Lechner, Arno Hintersteininger, Jan Marco Kern, Matthias Meißnitzer, Damian Meyersburg, Johann W. Bauer, Martin Laimer   +7 more
wiley   +1 more source

β‐Lactam Adjunctive Therapy Compared to Vancomycin or Daptomycin Monotherapy in Adult Patients With Methicillin‐Resistant Staphylococcus aureus Bacteremia: An Update Systematic Review, Meta‐Analysis, and Trial Sequential Analysis

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2025, Issue 1, 2025.
Background: This study evaluated the efficacy and safety of vancomycin (VAN) or daptomycin (DAP) combined with β‐lactams (BLs) versus monotherapy (STAN) for methicillin-resistant Staphylococcus aureus (MRSA) bacteremia. Methods: PubMed, Web of Science, Embase, and Cochrane Library were searched until September 30, 2024, for RCTs or cohort studies ...
Changyun Zhao, Wenchao Mao, Difan Lu, Kailun Cai, Changqin Chen, Weihang Hu, Shanmei Lv, Qi Yang, Timotius Ivan Hariyanto   +8 more
wiley   +1 more source

Dalbavancin in the Treatment of Bacteremia and Endocarditis in People with Barriers to Standard Care

Antibiotics, 2020
Introduction: Dalbavancin is an antibiotic administered by intravenous infusion weekly or bi-weekly and is currently FDA-approved only for treatment of skin and soft-tissue infections. It has shown promise, but is not considered the standard of care, for
Leama Ajaka, Emily Heil, Sarah Schmalzle
doaj   +1 more source

Real‐world evidence in the cloud: Tutorial on developing an end‐to‐end data and analytics pipeline using Amazon Web Services resources

Clinical and Translational Science, Volume 17, Issue 12, December 2024.
Abstract In the rapidly evolving landscape of healthcare and drug development, the ability to efficiently collect, process, and analyze large volumes of real‐world data (RWD) is critical for advancing drug development. This article provides a blueprint for establishing an end‐to‐end data and analytics pipeline in a cloud‐based environment. The pipeline
Wes Anderson, Roopal Bhatnagar, Keith Scollick, Marco Schito, Ramona Walls, Jagdeep T. Podichetty   +5 more
wiley   +1 more source

Efficacy and safety of vancomycin compared with those of alternative treatments for methicillin‐resistant Staphylococcus aureus infections: An umbrella review

Journal of Evidence-Based Medicine, Volume 17, Issue 4, Page 729-739, December 2024.
Abstract Objective To summarize the evidence on the efficacy and safety of vancomycin compared with those of alternative treatments in adult patients with methicillin‐resistant Staphylococcus aureus (MRSA) infection. Methods PubMed, Embase, and Web of Science were searched up to December 15, 2023, for systematic reviews and meta‐analyses comparing ...
Sujata Purja, Minji Kim, Yomna Elghanam, Hae Jung Shim, Eunyoung Kim   +4 more
wiley   +1 more source

Free Vascularized Scapula tip Flap to L5—S1 Vertebral Defect After Chronic Infection Related to Interbody Fusion Cage: A Case Report

Microsurgery, Volume 44, Issue 7, October 2024.
ABSTRACT Septic nonunion after vertebral fusion can lead to significant patient disability. The management of septic nonunions usually involves surgical debridement, bone fixation, and antibiotic therapy. Particularly challenging is lumbosacral vertebral nonunions, which necessitate a difficult surgical approach.
Frank O. F. Reilly, Ioannis Georgopoulos, Håkan Jonsson, Kevin Mani, Andrés Rodriguez‐Lorenzo, Nikos Schizas   +5 more
wiley   +1 more source