Results 81 to 90 of about 17,216 (256)

Aryl hydrocarbon receptor-induced activation of AIM2 inflammasome is mediated by MOMP and MPT: A vital therapeutic pathway for inflammation

Cell Reports
Summary: Understanding how mitochondrial dysfunction (MD) triggers damage-associated molecular pattern (DAMP) signaling could advance therapies for inflammatory diseases. While aryl hydrocarbon receptor (AHR) is implicated in MD-related inflammation, its
Min Chen, Zhiwei Liang, Mengyuan Sun, Zhen Chen, Chun Peng, Suliman Khan, Mubbashar Abbas, Dongmei Chen, Shuyu Xie   +8 more
doaj   +1 more source

Magnetic Textiles: A Review of Materials, Fabrication, Properties, and Applications

Advanced Materials Technologies, EarlyView.
Magnetic textiles (M‐textiles) are emerging as a programmable materials platform that merges magnetic matter with hierarchical textile structures. This article consolidates magnetic material classes, textile architectures, and fabrication and magnetization strategies, revealing structure–property–function relationships that govern magneto‐mechanical ...
Li Ke, Moses Kumi, Xiaoming Tao, Junhong Pu   +3 more
wiley   +1 more source

Bamboo Medical Application: A State‐of‐the‐Art Review

Advanced Materials Technologies, EarlyView.
This review presents a structured classification of bamboo's current use in healthcare. It organizes applications into medical textiles and medical devices, with further divisions based on function and level of invasiveness. It also examines material utilization based on bamboo's structural role, highlighting how it supports both protective and ...
Haymanot Beza Lamesgin, Koosje van der Stoel, Vera Popovich, Paul Breedveld   +3 more
wiley   +1 more source

Waveguide Photoactuators: Materials, Fabrication, and Applications

Advanced Robotics Research, EarlyView.
Waveguide photoactuators convert guided light into mechanical motion. Their tethered‐flexible design enables minimally invasive surgery and confined‐space robotics. This review aims to guide materials selection, device design, and system integration, accelerating the transition of waveguide photoactuators from laboratory prototypes to versatile ...
Minjie Xi, Hemin Pan, Yang Zong, Yongfeng Mei, Jizhai Cui   +4 more
wiley   +1 more source

Backpropagation Through Soft Body: Investigating Information Processing in Brain–Body Coupling Systems

Advanced Robotics Research, EarlyView.
This study explores how information processing is distributed between brains and bodies through a codesign approach. Using the “backpropagation through soft body” framework, brain–body coupling agents are developed and analyzed across several tasks in which output is generated through the agents’ physical dynamics.
Hiroki Tomioka, Katsuma Inoue, Yasuo Kuniyoshi, Kohei Nakajima   +3 more
wiley   +1 more source

Homeostasis of oligogalacturonides (OGs) and their activity as damage associated molecular patterns (DAMPs)

, 2021
Dottorato di ricerca in Scienze delle produzioni vegetali e ...
openaire   +1 more source

naRNA-LL37 composite DAMPs define sterile NETs as self-propagating drivers of inflammation

EMBO Reports
Neutrophil extracellular traps (NETs) are a key antimicrobial feature of cellular innate immunity mediated by polymorphonuclear neutrophils (PMNs). NETs counteract microbes but are also linked to inflammation in atherosclerosis, arthritis, or psoriasis ...
Francesca Bork, Carsten L Greve, Christine Youn, Sirui Chen, Vinicius N C Leal, Yu Wang, Berenice Fischer, Masoud Nasri, Jule Focken, Jasmin Scheurer, Pujan Engels, Marissa Dubbelaar, Katharina Hipp, Baher Zalat, Andras Szolek, Meng-Jen Wu, Birgit Schittek, Stefanie Bugl, Thomas A Kufer, Markus W Löffler, Mathias Chamaillard, Julia Skokowa, Daniela Kramer, Nathan K Archer, Alexander N R Weber   +24 more
doaj   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

Advanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong, Lingshuang Wang, Hui Zhang, Menghuan Li, Zhong Luo, Yan Hu, Chunyuan Cai   +6 more
wiley   +1 more source

HMGB1’in Kanser ve Tedavisiyle İlişkisi

Düzce Üniversitesi Bilim ve Teknoloji Dergisi, 2019
Yüksek mobilite grup kutusu 1 (HMGB1)histon olmayan DNA proteini olup, kısaca DAMP olarak ifade edilen(Damage-associated molecular pattern) tehlike sinyali veya alarmı olarak görevyapar.
Celal Güven, Eylem Taşkın Güven, Salih Tunç Kaya, Yusuf Sevgiler   +3 more
doaj   +1 more source