Results 71 to 80 of about 57,132 (265)

Damage Mechanics of Biological Tissues in Relation to Viscoelasticity. [PDF]

open access: yesJ Biomech Eng, 2023
Ateshian GA   +5 more
europepmc   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

Development of a damage rheological model and its application in the analysis of mechanical properties of jointed rock masses

open access: yesEnergy Science & Engineering, 2019
Fossil fuel resources (eg, coal, oil, and natural gas) exist in underground reservoirs, where discontinuities are widespread and influence the stability of rock structures.
Wendong Yang   +6 more
doaj   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan   +6 more
wiley   +1 more source

Sustainable bioplastics manufacturing from renewable sources

open access: yesFEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto   +6 more
wiley   +1 more source

Avaliação de deflexões em estruturas de concretoarmado utilizando mecânica do dano

open access: yesRevista IBRACON de Estruturas e Materiais
Este trabalho visa apresentar uma contribuição sobre uma proposta de abordagem para o cálculo de deslocamentos em estruturas de concreto armado em regime de serviço, sendo restrito o estudo ao caso de concretos C20 a C35.
J. J. C. Pituba, R. G. Delalibera
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

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