Results 81 to 90 of about 436,032 (358)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Some Models of Mechanics of Local Damage
Механика машин, механизмов и материалов, 2011 The technique for determination of local damage of complexly loaded mechanical system based on model of the deformable rigid body with dangerous volume is considered. Calculation of damage contact interaction is made.
O.M. Yelovoy
doaj
Investigation on the ductile fracture of a high-strength dual-phase steel with anisotropic damage mechanics model [PDF]
, 2021 Zinan Li +4 more
openalex +1 more source
A computational model coupling mechanics and electrophysiology in spinal cord injury [PDF]
, 2014 Traumatic brain injury and spinal cord injury have recently been put under the spotlight as major causes of death and disability in the developed world.
García Grajales, Julián Andrés +3 more
core +2 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Metals, 2015 In this study, fatigue crack growth rates (FCGR) of 7% nickel steel at room and cryogenic temperatures were evaluated using damage-coupled finite element analysis (FEA).
Seul-Kee Kim +6 more
doaj +1 more source
Boundary-domain integro-differential equation of elastic damage mechanics model of stationary drilling [PDF]
, 2005 Copyright @ 2005 EC ...
Mikhailov, SE
core
Mechanisms of Brain Damage in Twins [PDF]
Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 1982 SUMMARY:The brains of 18 twins dying in the perinatal period showed a variety of lesions. Eleven had subependymal cell plate hemorrhage which had ruptured into the lateral ventricles in five. Five had periventricular damage. Three had anoxic neuronal damage. One acardiac monster had bilateral cerebral infarction.
openaire +2 more sources
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source