Results 71 to 80 of about 1,342,747 (314)

Strategies for managing spring frost risks in orchards: effectiveness and conditionality—a systematic review

open access: yesEnvironmental Evidence, 2022
Background Spring frosts pose an important threat to orchard productivity in temperate zones and projections do not exclude damaging events in the future.
Bianca Drepper   +3 more
doaj   +1 more source

Effect of DNA repair deficiencies on the cytotoxicity of resveratrol [PDF]

open access: yes, 2015
Numerous preclinical studies have shown that the naturally-occurring polyphenol resveratrol may produce health-beneficial effects in a variety of disorders, including cancer, diabetes, Alzheimer, and cardiovascular diseases.
Burgos Morón, Estefanía   +5 more
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Associations of endocrine disrupting chemicals with renal function in older individuals

open access: yesHygiene and Environmental Health Advances
Background: Since the twentieth century, endocrine-disrupting substances (EDCs) such as phthalates and organophosphates have been utilised in various goods. The long-term usage of these products may have negative effects on people's health. Most EDCs are
Jiaoyang Chen   +8 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The Environmental Impact Assessment: a new tool for a new quality in ecological compliance

open access: yesTechne, 2013
The growing awareness that environmental protection is a top priority in terms of ethical, social as well as economic, has been determined since the 70's the definition of tools and procedures able to ensure control of the processes of transformation of ...
Maria Theresa Lucarelli
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The effects of childbirth on the pelvic-floor [PDF]

open access: yes, 2000
Basically, vaginal delivery is associated with the risk of pelvic floor damage. The pelvic floor sequelae of childbirth includes anal incontinence, urinary incontinence and pelvic organ prolapse.
Allen RE   +24 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Editorial: Damage control of plants—from the molecule to the entire plant

open access: yesFrontiers in Plant Science, 2023
Olga Speck   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy