Results 81 to 90 of about 172,653 (302)
Zhongguo Jianchuan YanjiuObjectiveThis study aims to calculate and analyze the capsizing probability of damaged vessels in beam seas under dead ship conditions, considering varying significant wave heights and characteristic wave periods.
Jianwen DUAN, Ning MA, Qiqi SHI
doaj +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Design implications of the new harmonised probabilistic damage stability regulations
, 2007 In anticipation of the forthcoming new harmonised regulations for damage stability, SOLAS Chapter II-1, proposed in IMO MSC 80 and due for enforcement in 2009, a number of ship owners and consequentially yards and classification societies are venturing ...
York, Anthony +4 more
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Safety level of damaged RoPax ships : risk modelling and cost-effectiveness analysis
, 2009 This paper elaborates on results of a recent risk analysis study for RoPax vessels, carried out as part of the activities of the SAFEDOR Integrated Project, targeting possible improvements on safety levels following large scale flooding.
Konovessis, D., Guarin, L., Vassalos, D.
core +1 more source
Detection of damaged props and their potential impact on structural stability during construction
Steel props play a key role in providing stability to floor slabs during construction. Their technical condition significantly affects expansion capability and safety.
Makýš, Peter, Švolík, Milan
core +2 more sources
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Oncogenesis, 2020 Human HLTF participates in the lesion-bypass mechanism through the fork reversal structure, known as template switching of post-replication repair. However, the mechanism by which HLTF promotes the replication progression and fork stability of damaged ...
Jia-Lin Shiu +10 more
doaj +1 more source
RNA damage and its implications in genome stability
DNA RepairEndogenous and environmental stressors can damage DNA and RNA to compromise genome and transcriptome stability and integrity in cells, leading to genetic instability and diseases. Recent studies have demonstrated that RNA damage can also modulate genome stability via RNA-templated DNA synthesis, suggesting that it is essential to maintain RNA integrity
Mustapha Olatunji, Yuan Liu
openaire +2 more sources
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Stability of Damaged Passenger Vessel [PDF]
, 2017 U posljednje vrijeme povećava se potreba za putničkim brodovima, a to se posebno odnosi na brodove za kružna putovanja. Zbog toga se grade sve veći i moderniji brodovi za kružna putovanja koji prevoze sve veći broj putnika, i upravo zbog toga najviše ...
Medić, Marko
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