Results 11 to 20 of about 50,688 (149)

Danger Signals in the ICU. [PDF]

Crit Care Med, 2018
Objectives: Sterile and infectious critical illnesses often result in vasoplegic shock and a robust systemic inflammatory response that are similar in presentation. The innate immune system is at the center of the response to both infectious and traumatic insults.
Schenck EJ, Ma KC, Murthy SB, Choi AMK.
europepmc   +4 more sources

Danger signals, inflammasomes, and the intricate intracellular lives of chlamydiae [PDF]

Biomedical Journal, 2016
Chlamydiae are obligate intracellular bacterial pathogens, and as such are sensitive to alterations in the cellular physiology of their hosts. Chlamydial infections often cause pathologic consequences due to prolonged localized inflammation. Considerable
Matthew A. Pettengill, Ali Abdul-Sater, Robson Coutinho-Silva, David M. Ojcius   +3 more
doaj   +2 more sources

Danger signals - damaged-self recognition across the tree of life [PDF]

Frontiers in Plant Science, 2014
Multicellular organisms suffer injury and serve as hosts for microorganisms. Therefore, they require mechanisms to detect injury and to distinguish the self from the non-self and the harmless non-self (microbial mutualists and commensals) from the ...
Martin eHeil, Walter G Land
doaj   +2 more sources

Editorial: Endogenous danger signals in cancer immunology and immunotherapy [PDF]

Frontiers in Immunology
Xiubao Ren, Jinming Gao, Jingting Jiang
doaj   +2 more sources

Editorial: Danger Signals Triggering Immune Response and Inflammation [PDF]

Frontiers in Immunology, 2017
Abdulraouf Ramadan, Abdulraouf Ramadan, Abdulraouf Ramadan, Walter G. Land, Walter G. Land, Sophie Paczesny, Sophie Paczesny, Sophie Paczesny   +7 more
doaj   +2 more sources

Knowledge of danger signals of pregnancy among clients of maternal health services in tertiary care teaching hospital, Pune

Asian Journal of Medical Sciences, 2021
Background: India is among countries with a high maternal mortality rate. Every pregnant woman is at risk of developing pregnancy-related complication.
Arunesh Kumar , Sachin Gupta , Prasad Pore   +2 more
doaj   +1 more source

Mechanical Stiffness Controls Dendritic Cell Metabolism and Function

Cell Reports, 2021
Summary: Stiffness in the tissue microenvironment changes in most diseases and immunological conditions, but its direct influence on the immune system is poorly understood.
Mainak Chakraborty, Kevin Chu, Annie Shrestha, Xavier S. Revelo, Xiangyue Zhang, Matthew J. Gold, Saad Khan, Megan Lee, Camille Huang, Masoud Akbari, Fanta Barrow, Yi Tao Chan, Helena Lei, Nicholas K. Kotoulas, Juan Jovel, Chiara Pastrello, Max Kotlyar, Cynthia Goh, Evangelos Michelakis, Xavier Clemente-Casares, Pamela S. Ohashi, Edgar G. Engleman, Shawn Winer, Igor Jurisica, Sue Tsai, Daniel A. Winer   +25 more
doaj   +1 more source

Detailed in vitro analyses of the impact of multimodal cancer therapy with hyperthermia and radiotherapy on the immune phenotype of human glioblastoma cells

International Journal of Hyperthermia, 2022
Purpose Improvements of heat-delivery systems have led to hyperthermia (HT) being increasingly recognized as an adjunct treatment modality also for brain tumors.
Eileen Stoll, Michael Hader, Michael Rückert, Thomas Weissmann, Sebastian Lettmaier, Florian Putz, Markus Hecht, Rainer Fietkau, Andreas Rosin, Benjamin Frey, Udo S. Gaipl   +10 more
doaj   +1 more source

Necroptosis in Immuno-Oncology and Cancer Immunotherapy

Cells, 2020
Immune-checkpoint blockers (ICBs) have revolutionized oncology and firmly established the subfield of immuno-oncology. Despite this renaissance, a subset of cancer patients remain unresponsive to ICBs due to widespread immuno-resistance.
Jenny Sprooten, Pieter De Wijngaert, Isaure Vanmeerbeek, Shaun Martin, Peter Vangheluwe, Susan Schlenner, Dmitri V. Krysko, Jan B. Parys, Geert Bultynck, Peter Vandenabeele, Abhishek D. Garg   +10 more
doaj   +1 more source

Trial watch: chemotherapy-induced immunogenic cell death in oncology

OncoImmunology, 2023
Immunogenic cell death (ICD) refers to an immunologically distinct process of regulated cell death that activates, rather than suppresses, innate and adaptive immune responses. Such responses culminate into T cell-driven immunity against antigens derived
Jenny Sprooten, Raquel S. Laureano, Isaure Vanmeerbeek, Jannes Govaerts, Stefan Naulaerts, Daniel M. Borras, Lisa Kinget, Jitka Fucíková, Radek Špíšek, Lenka Palová Jelínková, Oliver Kepp, Guido Kroemer, Dmitri V. Krysko, An Coosemans, Rianne D.W. Vaes, Dirk De Ruysscher, Steven De Vleeschouwer, Els Wauters, Evelien Smits, Sabine Tejpar, Benoit Beuselinck, Sigrid Hatse, Hans Wildiers, Paul M. Clement, Peter Vandenabeele, Laurence Zitvogel, Abhishek D. Garg   +26 more
doaj   +1 more source