Results 21 to 30 of about 50,688 (149)
Danger Signaling in Atherosclerosis [PDF]
Circulation Research, 2015 All aspects of the pathogenesis of atherosclerosis are critically influenced by the inflammatory response in vascular plaques. Research in the field of innate immunity from the past 2 decades has uncovered many novel mechanisms elucidating how immune cells sense microbes, tissue damage, and metabolic derangements.
Zimmer, Sebastian +2 more
openaire +3 more sources
Purinergic P2X7 receptor expression increases in leukocytes from intra-abdominal septic patients
Frontiers in Immunology, 2023 Inflammation is a tightly coordinated response of the host immune system to bacterial and viral infections, triggered by the production of inflammatory cytokines.
Helios Martínez-Banaclocha +15 more
doaj +1 more source
A Danger-Theory-Based Immune Network Optimization Algorithm
The Scientific World Journal, 2013 Existing artificial immune optimization algorithms reflect a number of shortcomings, such as premature convergence and poor local search ability. This paper proposes a danger-theory-based immune network optimization algorithm, named dt-aiNet.
Ruirui Zhang +3 more
doaj +1 more source
Frontiers in Immunology, 2013 Dendritic cells (DCs) initiate and control immune responses, participate in the maintenance of immunological tolerance and are pivotal players in the pathogenesis of autoimmunity.
Paul Matthew Gallo, Stefania eGallucci
doaj +1 more source
Oncolytic Newcastle Disease Virus as Cutting Edge between Tumor and Host
Biology, 2013 Oncolytic viruses (OVs) replicate selectively in tumor cells and exert anti-tumor cytotoxic activity. Among them, Newcastle Disease Virus (NDV), a bird RNA virus of the paramyxovirus family, appears outstanding.
Philippe Fournier, Volker Schirrmacher
doaj +1 more source
Alarmins, inflammasomes and immunity
Biomedical Journal, 2012 The elaboration of an effective immune response against pathogenic microbes such as viruses, intracellular bacteria or protozoan parasites relies on the recognition of microbial products called pathogen-associated molecular patterns (PAMPs) by pattern ...
Najwane Saïd-Sadier, David M Ojcius
doaj +1 more source
Why the Immune System Should Be Concerned by Nanomaterials?
Frontiers in Immunology, 2017 Particles possess huge specific surface area and therefore nanomaterials exhibit unique characteristics, such as special physical properties and chemical hyper-reactivity, which make them particularly attractive but also raise numerous questions ...
Marc J. Pallardy +2 more
doaj +1 more source
Alarm pheromone and kairomone detection via bitter taste receptors in the mouse Grueneberg ganglion
BMC Biology, 2018 Background The mouse Grueneberg ganglion (GG) is an olfactory subsystem specialized in the detection of volatile heterocyclic compounds signalling danger.
Fabian Moine +4 more
doaj +1 more source
BMC Immunology, 2008 Background Peripheral blood mononuclear cells (PBMC) serve a sentinel role allowing the host to efficiently sense and adapt to the presence of danger signals.
Sakthivel Bhuvaneswari +2 more
doaj +1 more source
HMGB1: Endogenous Danger Signaling
Molecular Medicine, 2008 While foreign pathogens and their products have long been known to activate the innate immune system, the recent recognition of a group of endogenous molecules that serve a similar function has provided a framework for understanding the overlap between the inflammatory responses activated by pathogens and injury.
Klune, John R +4 more
openaire +2 more sources