Results 121 to 130 of about 12,572 (254)

Magnesium lithospermate B protects cardiomyocytes from ischemic injury via inhibition of TAB1-p38 apoptosis signaling

open access: yesFrontiers in Pharmacology, 2010
Danshen has been used in traditional Chinese medicine (TCM) for hundreds of years to treat cardiovascular diseases. However, its precise cardioprotective components and the underlying mechanism are still unclear.
Chang-Sheng Du   +8 more
doaj   +1 more source

Dual blockage of STAT3 and ERK1/2 eliminates radioresistant GBM cells. [PDF]

open access: yes, 2019
Radiotherapy (RT) is the major modality for control of glioblastoma multiforme (GBM), the most aggressive brain tumor in adults with poor prognosis and low patient survival rate.
Duan, Yumei   +11 more
core   +1 more source

Danshen Inhibits Oxysterol-induced Endothelial Cell Apoptosis In Vivo

open access: yesJournal of Atherosclerosis and Thrombosis, 2005
Oxysterols induce apoptosis in vascular endothelial cells in vitro, but it is not clear whether they do so in vivo. We intravenously injected an oxysterol, cholestan-3beta, 5alpha, 6beta-triol, into rats and quantitatively analyzed endothelial cell apoptosis in the aorta. Oxysterol significantly promoted apoptosis in a time- and dose-dependent fashion.
Toru, Nakazawa   +7 more
openaire   +3 more sources

Quality Evaluation and Chemical Markers Screening of Salvia miltiorrhiza Bge. (Danshen) Based on HPLC Fingerprints and HPLC-MSn Coupled with Chemometrics

open access: yesMolecules, 2017
Danshen, the dried root of Salvia miltiorrhiza Bge., is a widely used commercially available herbal drug, and unstable quality of different samples is a current issue. This study focused on a comprehensive and systematic method combining fingerprints and
Wenyi Liang   +8 more
doaj   +1 more source

Isolation of Salvianolic acid A, a Minor Phenolic Carboxylic Acid of

open access: yesNatural Product Communications, 2010
Salvianolic acid A (Sal A), a caffeic acid derivative present in Salvia miltiorrhiza (Danshen), has shown significant biological activities, some of which are more potent than those of salvianolic acid (Sal B), the most abundant and bioactive compound in
Luyang Lu, Hao Zhang, Yu Qian, Yuan Yuan
doaj   +1 more source

Bioactive Phenolic Compounds from the Roots of Danshen ()

open access: yesNatural Product Communications, 2018
Danshen ( Salvia miltiorrhiza Bunge) is one of the most used medicinal plants in the Oriental medicine and has been well studied for application in modern medicine.
Nguyen Huu Tung   +6 more
doaj   +1 more source

Danshen enhanced the estrogenic effects of Qing E formula in ovariectomized rats [PDF]

open access: yes, 2016
Er-wei Liu   +8 more
core   +1 more source

Research Center for Ethnomedicines [PDF]

open access: yes, 2003
I. 伝統薬物に関するデータベース(ETHMEDmmm)の構築和漢薬・アーユルヴェーダ薬物データベースを新たに開発し,学術データの構築を開始した。Il. 伝統薬物の薬効の評価と解析に関する研究1 )難治性の神経疾患に対する有効性の検討とそれらの薬理作用の機序に関する研究インド生薬Ash wagandha から,ラット大脳皮質神経の初代培養細胞における神経突起伸展とシナプス形成作用を促進する成分を明らかにし,アルツハイマー病原因物質のアミロイドβ により障害を受けた神経細胞においても ...
Dawa   +4 more
core   +1 more source

Danshen: A Popular Chinese Cardiac Herbal Drug

open access: yesJournal of the American College of Cardiology, 2006
The recently published document in JACC on complementary and integrative medicine ([1][1]) left out one very important herbal drug, danshen. Because it is believed to have properties of improving microcirculation, increasing coronary blood flow, suppressing thromboxane formation, inhibiting ...
openaire   +1 more source

Modelling and Optimization of the (R)-(+)-3,4-dihydroxyphenyllactic Acid Production Catalyzed with D-lactate Dehydrogenase from Lactobacillus leishmannii Using Genetic Algorithm [PDF]

open access: yes, 2005
A mathematical model for the enzymatic kinetics of the synthesis of (R)–(+)–3,4-dihydroxyphenyllactic acid (DHPL) was developed. The synthesis was catalyzed by D-lactate dehydrogenase from Lactobacillus leishmannii.
M. Poljanac   +2 more
core   +1 more source

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