Results 91 to 100 of about 9,798 (259)

Acute postoperative sepsis mimicking symptomology suspicious for malignant hyperthermia: case report

Brazilian Journal of Anesthesiology, 2019
Background: Sepsis is a life-threatening organ dysfunction with non-specific clinical features that can mimic other clinical conditions with hyper metabolic state such as malignant hyperthermia.
Vendhan Ramanujam, Christopher R. Hoffman, Kevin Russo, Michael S. Green   +3 more
doaj   +1 more source

Characterization of Novel WFS1 Variants in Three Diabetes Pedigrees

Journal of Diabetes, Volume 17, Issue 7, July 2025.
We first collected the patients with diabetes, including the clinical data and blood. Then the high‐throughput sequencing platform was used to detected gene mutation using blood samples. After screening the possible mutation sites, we collected blood from the patient's family members and performed Sanger sequencing for verification.
ChangQing Liu, HangYu Fang, Dong Wang, YiPing Cheng, Ping Shi, ChunXiao Yu, XiaoHong Li, Hui Zhao, Wei Hou, ZhenKui Guo, Chao Xu, QingBo Guan   +11 more
wiley   +1 more source

Recrudescência fatal de hipertermia maligna em lactente com síndrome de Moebius. Relato de caso

Revista Brasileira de Anestesiologia, 2013
JUSTIFICATIVA E OBJETIVOS: A hipertermia maligna (HM) é uma desordem farmacogenética da musculatura esquelética, caracterizada por estado hipermetabólico após anestesia com succinilcolina e/ou agentes anestésicos voláteis.
Cláudia Regina Fernandes, Washington Aspiculeta Pinto Filho, Lia Cavalcante Cezar, Josenília Maria Alves Gomes, Glauco Kleming Florencio da Cunha   +4 more
doaj   +1 more source

The potential for one drug, administered at the earliest preclinical stage, to prevent the subsequent decline of cognition that eventuates in dementia

Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 2020
In the process that eventuates in mild cognitive impairment (MCI) and ultimately in Alzheimer's dementia, the earliest identifiable change is in the function of synapses.
Jeffrey Fessel
doaj   +1 more source

Fatal Recrudescence of Malignant Hyperthermia in an Infant with Moebius Syndrome

Brazilian Journal of Anesthesiology, 2013
Background and objectives: Malignant hyperthermia (MH) is a pharmacogenetic skeletal muscle disorder characterized by a hypermetabolic state after anesthesia with succinylcholine and/or volatile anesthetics. Various neuromuscular syndromes are associated
Cláudia Regina Fernandes, Washington Aspiculeta Pinto Filho, Lia Cavalcante Cezar, Josenília Maria Alves Gomes, Glauco Kleming Florencio da Cunha   +4 more
doaj   +1 more source

Dantrolene is not the answer to 2,4-dinitrophenol poisoning: more heated debate

BMJ Case Reports, 2018
There has been a resurgence in the use of 2,4-dinitrophenol, C6H4N2O5 (DNP) recently as an illegal weight loss drug. We present a case of a healthy 25-year-old girl who took two tablets of DNP, purchased from an overseas online retailer.
Jason Van Schoor, Esha Khanderia, A. Thorniley   +2 more
semanticscholar   +1 more source

Post-Anesthesia Cognitive Dysfunction in Mice Is Associated with an Age-Related Increase in Neuronal Intracellular [Ca²⁺]—Neuroprotective Effect of Reducing Intracellular [Ca²⁺]: In Vivo and In Vitro Studies

Cells
Background: Postoperative cognitive dysfunction (POCD) is a common disorder after general anesthesia in elderly patients, the precise mechanisms of which remain unclear.
Arkady Uryash, Alfredo Mijares, Carlos E. Lopez, Jose A. Adams, Paul D. Allen, Jose R. Lopez   +5 more
doaj   +1 more source

Does prior dantrolene affect thein vitro diagnosis of malignant hyperthermia susceptibility? [PDF]

, 1979
T. E. Nelson, E. H. Flewellen
openalex   +1 more source

THE EFFECTS OF GLYCEROL DETUBULATION, OF MANGANESE IONS, OF DANTROLENE AND OF NITRATE IONS ON THE RESPONSES OF ISOLATED CHRONICALLY DENERVATED SOLEUS MUSCLES OF THE MOUSE TO ACETYLCHOLINE [PDF]

, 1978
Moira T. Hall, M A Maleque, R. M. Wadsworth   +2 more
openalex   +1 more source

Dantrolene versus amiodarone for cardiopulmonary resuscitation: a randomized, double-blinded experimental study

Scientific Reports, 2017
Dantrolene was introduced for treatment of malignant hyperthermia. It also has antiarrhythmic properties and may thus be an alternative to amiodarone for the treatment of ventricular fibrillation (VF).
T. Wiesmann, D. Freitag, W. Dersch, D. Eschbach, M. Irqsusi, T. Steinfeldt, H. Wulf, Carsten Feldmann   +7 more
semanticscholar   +1 more source